{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,12]],"date-time":"2025-11-12T03:14:26Z","timestamp":1762917266341,"version":"3.38.0"},"reference-count":15,"publisher":"SAGE Publications","issue":"2","license":[{"start":{"date-parts":[[2010,7,1]],"date-time":"2010-07-01T00:00:00Z","timestamp":1277942400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["World J Pediatr Congenit Heart Surg"],"published-print":{"date-parts":[[2010,7]]},"abstract":"<jats:p> Irreparable mitral pathology may lead to early mitral valve replacement (MVR) in children. Often, a small mechanical prosthesis (&lt;23 mm) is required, raising concerns about annular growth in patients who may eventually require subsequent mitral valve re-replacement (MVRR). The aim of this study was to evaluate interval mitral annular growth in this cohort. Between January 1972 and December 2006, 164 children underwent MVR with a mechanical prosthesis; 110 of these children (median age, 4 years; range, 7 days to 14 years) received a small mechanical prosthesis (&lt;23 mm). The most common diagnoses were congenital mitral stenosis (10%), regurgitation (46%), and left atrioventricular valve dysfunction after previous atrioventricular septal defect repair (44%). The cohort was analyzed for age, body surface area (BSA), prosthesis size, and Z score at the time of MVR and MVRR. At the time of MVR, 78 patients had a BSA of 0.77 \u00b1 0.06 m<jats:sup>2<\/jats:sup>, had an annular size of 24 \u00b1 0.62 mm ( Z score, 2.91 \u00b1 0.23), and ultimately did not require MVRR. Another cohort, who eventually did require MVRR (n = 24), had an initial BSA at the time of MVR of 0.62 \u00b1 0.05 m<jats:sup>2<\/jats:sup> ( P = NS vs MVR only) and an annular size of 20 \u00b1 0.49 mm ( Z score, 1.85 \u00b1 0.22) ( P = .008 vs MVR only). In the interval between MVR and MVRR (7.8 \u00b1 1.1 years), BSA increased to 1.12 \u00b1 0.07 m<jats:sup>2<\/jats:sup>, and annulus size increased to 24 \u00b1 0.47 mm ( Z score, 1.80 \u00b1 0.28). These data suggest growth of the mitral annulus following MVR with a small mechanical prosthesis, as evidenced by an unchanged Z score in the setting of normal interval increase in BSA. Additionally, there was a statistically significant difference in initial Z scores between the cohorts requiring MVRR and those who have not needed re-replacement, suggesting that the feasibility of placement of a slightly larger prosthesis may be associated with a decreased need for MVRR. <\/jats:p>","DOI":"10.1177\/2150135110371487","type":"journal-article","created":{"date-parts":[[2010,7,20]],"date-time":"2010-07-20T18:28:59Z","timestamp":1279650539000},"page":"177-181","source":"Crossref","is-referenced-by-count":6,"title":["Mitral Annular Growth in Children Following Early Mechanical Mitral Valve Replacement"],"prefix":"10.1177","volume":"1","author":[{"suffix":"III","given":"Lucian A.","family":"Durham","sequence":"first","affiliation":[{"name":"Division of Cardiovascular Surgery, Mayo Clinic, Rochester, Minnesota"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Harold M.","family":"Burkhart","sequence":"additional","affiliation":[{"name":"Division of Cardiovascular Surgery, Mayo Clinic, Rochester, Minnesota"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joseph A.","family":"Dearani","sequence":"additional","affiliation":[{"name":"Division of Cardiovascular Surgery, Mayo Clinic, Rochester, Minnesota"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Francisco J.","family":"Puga","sequence":"additional","affiliation":[{"name":"Division of Cardiovascular Surgery, Mayo Clinic, Rochester, Minnesota"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Patrick W.","family":"O\u2019Leary","sequence":"additional","affiliation":[{"name":"Division of Pediatric Cardiology, Mayo Clinic, Rochester, Minnesota"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hartzell V.","family":"Schaff","sequence":"additional","affiliation":[{"name":"Division of Cardiovascular Surgery, Mayo Clinic, Rochester, Minnesota"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2010,7,20]]},"reference":[{"key":"bibr1-2150135110371487","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.43.4.565"},{"key":"bibr2-2150135110371487","doi-asserted-by":"publisher","DOI":"10.1016\/j.athoracsur.2009.02.048"},{"key":"bibr3-2150135110371487","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtcvs.2005.03.025"},{"key":"bibr4-2150135110371487","doi-asserted-by":"publisher","DOI":"10.1053\/j.pcsu.2009.02.002"},{"key":"bibr5-2150135110371487","first-page":"25","volume":"12","author":"Erez E","year":"2003","journal-title":"J Heart Valve Dis"},{"key":"bibr6-2150135110371487","doi-asserted-by":"publisher","DOI":"10.1136\/heart.84.6.636"},{"key":"bibr7-2150135110371487","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtcvs.2004.07.024"},{"key":"bibr8-2150135110371487","doi-asserted-by":"publisher","DOI":"10.1007\/s11748-005-0065-z"},{"key":"bibr9-2150135110371487","doi-asserted-by":"publisher","DOI":"10.1016\/j.echo.2008.02.006"},{"issue":"1","key":"bibr10-2150135110371487","doi-asserted-by":"crossref","first-page":"I-143","DOI":"10.1161\/hc37t1.094840","volume":"104","author":"Calderone CA","year":"2001","journal-title":"Circulation"},{"key":"bibr11-2150135110371487","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejcts.2006.01.045"},{"key":"bibr12-2150135110371487","doi-asserted-by":"publisher","DOI":"10.1017\/S1047951106000746"},{"key":"bibr13-2150135110371487","doi-asserted-by":"publisher","DOI":"10.1016\/j.athoracsur.2005.02.052"},{"key":"bibr14-2150135110371487","doi-asserted-by":"publisher","DOI":"10.1016\/j.athoracsur.2003.09.066"},{"key":"bibr15-2150135110371487","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtcvs.2007.04.025"}],"container-title":["World Journal for Pediatric and Congenital Heart Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/2150135110371487","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/2150135110371487","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/2150135110371487","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,3,3]],"date-time":"2025-03-03T05:55:09Z","timestamp":1740981309000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/2150135110371487"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,7]]},"references-count":15,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2010,7]]}},"alternative-id":["10.1177\/2150135110371487"],"URL":"https:\/\/doi.org\/10.1177\/2150135110371487","relation":{},"ISSN":["2150-1351","2150-136X"],"issn-type":[{"type":"print","value":"2150-1351"},{"type":"electronic","value":"2150-136X"}],"subject":[],"published":{"date-parts":[[2010,7]]}}}