{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,1,28]],"date-time":"2025-01-28T05:45:28Z","timestamp":1738043128596,"version":"3.33.0"},"reference-count":9,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[2012,1,1]],"date-time":"2012-01-01T00:00:00Z","timestamp":1325376000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["World J Pediatr Congenit Heart Surg"],"published-print":{"date-parts":[[2012,1]]},"abstract":"<jats:p> In the accompanying article, Chenu and colleagues describe \u201can uncommon course of the right superior vena cava in a patient with heterotaxy syndrome.\u201d In their discussion, they pose the question, \u201cIs this an isolated atrial inversion, or a case of left isomerism?\u201d They proceed to comment \u201cthis remains a debate among cardiac morphologists.\u201d I can agree with them on their first description, since although I have previously examined many hearts from patients with isomerism of the left atrial appendages, or \u201cpolysplenia syndrome,\u201d I had not noticed the unusual feature they have emphasized in their case report; although, as I will show, the evidence was there for me to observe their feature of emphasis. They deserve great credit, therefore, for bringing this feature to our attention. I also agree with their first statement, namely that their patient has the left isomeric variant of the so-called visceral heterotaxy, but I must question their suggestion that the patient may exhibit mirror-imaged arrangement of the atrial chambers or \u201catrial situs inversus.\u201d I would question even more strongly their comment that the distinction remains \u201ca debate among cardiac morphologists.\u201d As I will further show, the distinction has major clinical implications, not only for pediatric cardiac surgeons but also for those involved with genetic counseling. <\/jats:p>","DOI":"10.1177\/2150135111422721","type":"journal-article","created":{"date-parts":[[2012,1,11]],"date-time":"2012-01-11T18:52:04Z","timestamp":1326307924000},"page":"133-135","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Invited Commentary: Left Isomerism or \u201cIsolated Atrial Inversion\u201d?"],"prefix":"10.1177","volume":"3","author":[{"given":"Robert H.","family":"Anderson","sequence":"first","affiliation":[{"name":"Institute of Human Genetics, Newcastle University, Newcaste-upon-Tyne United Kingdom, London, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2012,1,11]]},"reference":[{"issue":"1","key":"bibr1-2150135111422721","first-page":"130","volume":"3","author":"Chenu C","year":"2011","journal-title":"World J Pediatr Cardiac Surg"},{"doi-asserted-by":"publisher","key":"bibr2-2150135111422721","DOI":"10.1016\/0003-4975(95)00538-V"},{"doi-asserted-by":"publisher","key":"bibr3-2150135111422721","DOI":"10.1161\/circ.61.5.7363431"},{"doi-asserted-by":"publisher","key":"bibr4-2150135111422721","DOI":"10.1136\/hrt.44.6.657"},{"doi-asserted-by":"publisher","key":"bibr5-2150135111422721","DOI":"10.1016\/0002-9149(90)90543-A"},{"doi-asserted-by":"publisher","key":"bibr6-2150135111422721","DOI":"10.1038\/ng1446"},{"doi-asserted-by":"publisher","key":"bibr7-2150135111422721","DOI":"10.1111\/j.1469-7580.2009.01087.x"},{"key":"bibr8-2150135111422721","first-page":"1303","volume":"11","author":"Van Mierop LHS","year":"1962","journal-title":"Lab Invest"},{"doi-asserted-by":"publisher","key":"bibr9-2150135111422721","DOI":"10.1017\/S1047951106000382"}],"container-title":["World Journal for Pediatric and Congenital Heart Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/2150135111422721","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/2150135111422721","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/2150135111422721","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,1,27]],"date-time":"2025-01-27T20:46:18Z","timestamp":1738010778000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/2150135111422721"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,1]]},"references-count":9,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2012,1]]}},"alternative-id":["10.1177\/2150135111422721"],"URL":"https:\/\/doi.org\/10.1177\/2150135111422721","relation":{},"ISSN":["2150-1351","2150-136X"],"issn-type":[{"type":"print","value":"2150-1351"},{"type":"electronic","value":"2150-136X"}],"subject":[],"published":{"date-parts":[[2012,1]]}}}