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Due to progressive respiratory deterioration, she required surgical PDA interruption, extracorporeal life support, and subsequent prolonged respiratory support. Genetic testing revealed ACTA2 R179H mutation and cystic lung disease on biopsy.<\/jats:p>","DOI":"10.1177\/2150135116658457","type":"journal-article","created":{"date-parts":[[2016,8,22]],"date-time":"2016-08-22T22:49:18Z","timestamp":1471906158000},"page":"750-753","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":4,"title":["Extracorporeal Life Support in Multisystem Smooth Muscle Dysfunction Syndrome"],"prefix":"10.1177","volume":"8","author":[{"given":"Sudesh","family":"Prabhu","sequence":"first","affiliation":[{"name":"Queensland Paediatric Cardiac Services, Lady Cilento Children\u2019s Hospital, Brisbane, Queensland, Australia"},{"name":"School of Medicine, University of Queensland, Brisbane, Queensland, Australia"},{"name":"Mater Medical Research Institute, Brisbane, Queensland, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Scott","family":"Fox","sequence":"additional","affiliation":[{"name":"Queensland Paediatric Cardiac Services, Lady Cilento Children\u2019s Hospital, Brisbane, Queensland, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Adrian","family":"Mattke","sequence":"additional","affiliation":[{"name":"Queensland Paediatric Cardiac Services, Lady Cilento Children\u2019s Hospital, Brisbane, Queensland, Australia"},{"name":"School of Medicine, University of Queensland, Brisbane, Queensland, Australia"},{"name":"Mater Medical Research Institute, Brisbane, Queensland, Australia"},{"name":"Paediatric Intensive Care, Lady Cilento Children\u2019s Hospital, Brisbane, Queensland, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jane E.","family":"Armes","sequence":"additional","affiliation":[{"name":"School of Medicine, University of Queensland, Brisbane, Queensland, Australia"},{"name":"Mater Medical Research Institute, Brisbane, Queensland, Australia"},{"name":"Anatomic Pathology, Mater Health Services, Brisbane, Queensland, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nelson","family":"Alphonso","sequence":"additional","affiliation":[{"name":"Queensland Paediatric Cardiac Services, Lady Cilento Children\u2019s Hospital, Brisbane, Queensland, Australia"},{"name":"School of Medicine, University of Queensland, Brisbane, Queensland, Australia"},{"name":"Mater Medical Research Institute, Brisbane, Queensland, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2016,8,22]]},"reference":[{"key":"bibr1-2150135116658457","doi-asserted-by":"publisher","DOI":"10.1038\/ng.2007.6"},{"key":"bibr2-2150135116658457","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.a.33657"},{"issue":"4","key":"bibr3-2150135116658457","first-page":"509","volume":"120","author":"Graf MH","year":"2002","journal-title":"Arch Ophthalmol"},{"key":"bibr4-2150135116658457","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0420.2005.00496.x"},{"key":"bibr5-2150135116658457","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.a.30341"},{"key":"bibr6-2150135116658457","doi-asserted-by":"publisher","DOI":"10.1038\/ejhg.2010.239"},{"key":"bibr7-2150135116658457","doi-asserted-by":"publisher","DOI":"10.1097\/WNO.0000000000000090"},{"key":"bibr8-2150135116658457","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/aws172"}],"container-title":["World Journal for Pediatric and Congenital Heart Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/2150135116658457","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/2150135116658457","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/2150135116658457","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T23:20:10Z","timestamp":1777591210000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/2150135116658457"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,8,22]]},"references-count":8,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2017,11]]}},"alternative-id":["10.1177\/2150135116658457"],"URL":"https:\/\/doi.org\/10.1177\/2150135116658457","relation":{},"ISSN":["2150-1351","2150-136X"],"issn-type":[{"value":"2150-1351","type":"print"},{"value":"2150-136X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,8,22]]}}}