{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T07:07:23Z","timestamp":1777878443178,"version":"3.51.4"},"reference-count":29,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[2016,12,29]],"date-time":"2016-12-29T00:00:00Z","timestamp":1482969600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["World J Pediatr Congenit Heart Surg"],"published-print":{"date-parts":[[2017,1]]},"abstract":"<jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>The goals following pulmonary valve replacement (PVR) are to optimize right ventricular hemodynamics and minimize the need for subsequent reoperations on the right ventricular outflow tract. We hypothesized PVR using a xenograft valved conduit would result in superior freedom from reoperation with sustained improvement in right ventricular chamber dimensions.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>Xenograft valved conduits placed in patients aged &gt;16 years were reviewed from 2000 to 2010 to allow for a 5-year minimum follow-up. Preoperative, one-year, and the most recent echocardiograms quantified right ventricular chamber dimensions, corresponding Z scores, and prosthetic valve function. Magnetic resonance imaging (MRI) studies compared preoperative and follow-up right ventricular volumes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>A total of 100 patients underwent PVR at 24 (19-34) years. Freedom from reintervention was 100% at 10 years. At most recent follow-up, only one patient had greater than mild pulmonary insufficiency. The one-year (17.3 \u00b1 7.2 mm Hg; P &lt; .01) and most recent follow-up (18.6 \u00b1 9.8 mm Hg; P &lt; .01) Doppler-derived right ventricular outflow tract gradients remained significantly lower than preoperative measurements (36.7 \u00b1 27.0 mm Hg). Similarly, right ventricular basal diameter, basal longitudinal diameter, and the corresponding Z scores remained lower at one year and follow-up from preoperative measurements. From 34 MRI studies, the right ventricular end-diastolic indexed volume (161.7 \u00b1 58.5 vs 102.9 \u00b1 38.3; P &lt; .01) and pulmonary regurgitant fraction (38.0% \u00b1 15.9% vs 0.8% \u00b1 3.3%; P &lt; .01) were significantly lower at 7.1 \u00b1 3.4 years compared to the preoperative levels.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>Use of a xenograft valved conduit for PVR results in excellent freedom from reoperation with sustained improvement in right ventricular dimensions at an intermediate-term follow-up.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/2150135116670632","type":"journal-article","created":{"date-parts":[[2017,1,7]],"date-time":"2017-01-07T06:07:19Z","timestamp":1483769239000},"page":"39-47","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":1,"title":["Sustained Improvement in Right Ventricular Chamber Dimensions 10 Years Following Xenograft Pulmonary Valve Replacement"],"prefix":"10.1177","volume":"8","author":[{"given":"Heidi B.","family":"Schubmehl","sequence":"first","affiliation":[{"name":"University of Rochester Medical Center, Rochester, NY, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael F.","family":"Swartz","sequence":"additional","affiliation":[{"name":"University of Rochester Medical Center, Rochester, NY, USA"},{"name":"Pediatric Cardiac Consortium of Upstate, New York, NY, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nader","family":"Atallah-Yunes","sequence":"additional","affiliation":[{"name":"University of Rochester Medical Center, Rochester, NY, USA"},{"name":"Pediatric Cardiac Consortium of Upstate, New York, NY, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carol","family":"Wittlieb-Weber","sequence":"additional","affiliation":[{"name":"University 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