{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,29]],"date-time":"2026-10-29T17:47:55Z","timestamp":1793296075814,"version":"4.5.0"},"reference-count":11,"publisher":"SAGE Publications","issue":"4","license":[{"start":{"date-parts":[[2018,6,26]],"date-time":"2018-06-26T00:00:00Z","timestamp":1529971200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["World J Pediatr Congenit Heart Surg"],"published-print":{"date-parts":[[2018,7]]},"abstract":"<jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>Sternal wound infections after pediatric cardiac surgery are uncommon but can be morbid.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>We describe an institutional protocol for complicated sternal wounds utilizing hyperbaric oxygen therapy (HBO) and negative pressure wound therapy (NPWT).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Participants:<\/jats:title>\n                    <jats:p>A retrospective chart review (2001-2013) of 4,028 pediatric cardiac operations in 3,264 patients less than 18 years of age.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      Fifty-three patients (1.62%; 53\/3,264) were diagnosed with clinical sternal wound infections. There were 27 (50.9%) males and 26 (49.1%) females. Thirty-seven (69.8%) patients received antibiotics and\/or debridement; sixteen (30.2%) patients had more complicated infections requiring NPWT and\/or HBO therapy. The time to heal for wounds treated with HBO and HBO + NPWT was a mean of 43.75 (\u00b124.27) days (range: 21-98 days; median: 35 days). Among all infected patients, the time from diagnosis of the infection to resolution of the infection for all survivors was 7 to 98 days (mean: 26.41 days; median: 21 days). Forty-eight (90.6%) patients completely healed their wounds, and 45 (84.9%) patients are currently alive. Thirty-eight patients had a cyanotic cardiac diagnosis and 15 had an acyanotic cardiac diagnosis. The most common bacteria isolated from the blood or wound cultures was\n                      <jats:italic toggle=\"yes\">Staphylococcus aureus<\/jats:italic>\n                      . Six of 53 patients died. Causes of death are as follows: three from respiratory failure, one from sepsis, one from hypoxic ischemic encephalopathy, and one from exsanguination leading to cardiac arrest\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>Complicated sternal wound infections after pediatric cardiac surgery refractory to antibiotic therapy and\/or debridement can be successfully treated with NPWT and\/or HBO therapy.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/2150135118772494","type":"journal-article","created":{"date-parts":[[2018,6,26]],"date-time":"2018-06-26T23:51:15Z","timestamp":1530057075000},"page":"440-445","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":13,"title":["Role of Negative Pressure Wound Care and Hyperbaric Oxygen Therapy for Sternal Wound Infections After Pediatric Cardiac Surgery"],"prefix":"10.1177","volume":"9","author":[{"given":"Hannah","family":"Copeland","sequence":"first","affiliation":[{"name":"Division of Cardiothoracic Surgery, Department of Surgery, University of Mississippi Medical Center, Jackson, MS, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jennifer","family":"Newcombe","sequence":"additional","affiliation":[{"name":"Children\u2019s Hospital, Loma Linda University, Loma Linda, CA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Feras","family":"Yamin","sequence":"additional","affiliation":[{"name":"Texas Tech University Health Science Center, El Paso, TX, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Khaled","family":"Bhajri","sequence":"additional","affiliation":[{"name":"Loma Linda University School of Public Health, Loma Linda, CA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vanessa Ayer","family":"Mille","sequence":"additional","affiliation":[{"name":"Department of Thoracic and Cardiovascular Surgery, Loma Linda University, Loma Linda, CA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nahidh","family":"Hasaniya","sequence":"additional","affiliation":[{"name":"Department of Thoracic and Cardiovascular Surgery, Loma Linda University, Loma Linda, CA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leonard","family":"Bailey","sequence":"additional","affiliation":[{"name":"Department of Thoracic and Cardiovascular Surgery, Loma Linda University, Loma Linda, CA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anees J.","family":"Razzouk","sequence":"additional","affiliation":[{"name":"Department of Thoracic and Cardiovascular Surgery, Loma Linda University, Loma Linda, CA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2018,6,26]]},"reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1186\/1749-8090-4-5"},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.1111\/jocs.12243"},{"key":"e_1_3_3_4_2","doi-asserted-by":"publisher","DOI":"10.1186\/1749-8090-5-75"},{"key":"e_1_3_3_5_2","doi-asserted-by":"publisher","DOI":"10.12968\/jowc.2014.23.1.31"},{"key":"e_1_3_3_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1569-9293(03)00184-1"},{"key":"e_1_3_3_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejcts.2010.01.028"},{"key":"e_1_3_3_8_2","doi-asserted-by":"publisher","DOI":"10.1093\/icvts\/ivs254"},{"key":"e_1_3_3_9_2","doi-asserted-by":"publisher","DOI":"10.1510\/icvts.2005.122424"},{"key":"e_1_3_3_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.athoracsur.2007.09.004"},{"key":"e_1_3_3_11_2","doi-asserted-by":"publisher","DOI":"10.1093\/icvts\/ivw141"},{"key":"e_1_3_3_12_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00268-007-9109-0"}],"container-title":["World 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