{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,20]],"date-time":"2026-06-20T01:37:56Z","timestamp":1781919476054,"version":"3.54.5"},"reference-count":13,"publisher":"SAGE Publications","issue":"3","license":[{"start":{"date-parts":[[2019,5,1]],"date-time":"2019-05-01T00:00:00Z","timestamp":1556668800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["World J Pediatr Congenit Heart Surg"],"published-print":{"date-parts":[[2019,5]]},"abstract":"<jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>Given the shortage of donor organs in pediatric heart transplantation (HTx), pretransplant risk stratification may assist in organ allocation and recipient optimization. We sought to construct a scoring system to preoperatively stratify a patient\u2019s risk of one-year mortality after HTx.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>The United Network for Organ Sharing database was queried for pediatric (&lt;18 years) patients undergoing HTx between 2000 and 2016. The population was randomly divided in a 4:1 fashion into derivation and validation cohorts. A multivariable logistic regression model for one-year mortality was constructed within the derivation cohort. Points were then assigned to independent predictors ( P &lt; .05) based on relative odds ratios (ORs). Risk groups were established based on easily applicable, whole-integer score cutoffs.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>A total of 5,700 patients underwent HTx; one-year mortality was 10.7%. There was a similar distribution of variables between derivation (n = 4,560) and validation (n = 1,140) cohorts. Of the 12 covariates included in the final model, nine were allotted point values. The low-risk (score 0-9), intermediate-risk (10-20), and high-risk (&gt;20) groups had a 5.18%, 10%, and 28% risk of one-year mortality ( P &lt; .001), respectively. Both intermediate-risk (OR = 2.46, 95% confidence interval [95% CI]: 1.93-3.15; P &lt; .001) and high-risk (OR = 9.24, 95% CI: 6.92-12.35; P &lt; .001) scores were associated with an increased risk of one-year mortality when compared to the low-risk group.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>The Children\u2019s Heart Assessment Tool for Transplantation score represents a pediatric-specific, recipient-based system to predict one-year mortality after HTx. Its use could assist providers in identification of patients at highest risk of poor outcomes and may aid in pretransplant optimization of these children.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/2150135119830089","type":"journal-article","created":{"date-parts":[[2019,5,14]],"date-time":"2019-05-14T01:10:50Z","timestamp":1557796250000},"page":"296-303","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":5,"title":["Children\u2019s Heart Assessment Tool for Transplantation (CHAT) Score: A Novel Risk Score Predicts Survival After Pediatric Heart Transplantation"],"prefix":"10.1177","volume":"10","author":[{"suffix":"III","given":"Charles D.","family":"Fraser","sequence":"first","affiliation":[{"name":"Division of Cardiac Surgery, The Johns Hopkins Hospital, Baltimore, MD, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joshua C.","family":"Grimm","sequence":"additional","affiliation":[{"name":"Division of Cardiac Surgery, The Johns Hopkins Hospital, Baltimore, MD, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xun","family":"Zhou","sequence":"additional","affiliation":[{"name":"Division of Cardiac Surgery, The Johns Hopkins Hospital, Baltimore, MD, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cecillia","family":"Lui","sequence":"additional","affiliation":[{"name":"Division of Cardiac Surgery, The Johns Hopkins Hospital, Baltimore, MD, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2260-1854","authenticated-orcid":false,"given":"Kate","family":"Giuliano","sequence":"additional","affiliation":[{"name":"Division of Cardiac Surgery, The Johns Hopkins Hospital, Baltimore, MD, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alejandro","family":"Suarez-Pierre","sequence":"additional","affiliation":[{"name":"Division of Cardiac Surgery, The Johns Hopkins Hospital, Baltimore, MD, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Todd C.","family":"Crawford","sequence":"additional","affiliation":[{"name":"Division of Cardiac Surgery, The Johns Hopkins Hospital, Baltimore, MD, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J. Trent","family":"Magruder","sequence":"additional","affiliation":[{"name":"Division of Cardiac Surgery, The Johns Hopkins Hospital, Baltimore, MD, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Narutoshi","family":"Hibino","sequence":"additional","affiliation":[{"name":"Division of Cardiac Surgery, The Johns Hopkins Hospital, Baltimore, MD, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luca A.","family":"Vricella","sequence":"additional","affiliation":[{"name":"Division of Cardiac Surgery, The Johns Hopkins Hospital, Baltimore, MD, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2019,5,13]]},"reference":[{"key":"bibr1-2150135119830089","doi-asserted-by":"publisher","DOI":"10.1016\/j.athoracsur.2011.12.055"},{"key":"bibr2-2150135119830089","doi-asserted-by":"publisher","DOI":"10.1016\/j.healun.2017.03.002"},{"key":"bibr3-2150135119830089","doi-asserted-by":"publisher","DOI":"10.1016\/j.athoracsur.2011.04.030"},{"key":"bibr4-2150135119830089","doi-asserted-by":"publisher","DOI":"10.1016\/j.athoracsur.2015.07.026"},{"key":"bibr5-2150135119830089","doi-asserted-by":"publisher","DOI":"10.1016\/j.healun.2015.07.001"},{"key":"bibr6-2150135119830089","doi-asserted-by":"publisher","DOI":"10.1016\/j.athoracsur.2015.06.063"},{"key":"bibr7-2150135119830089","doi-asserted-by":"publisher","DOI":"10.1002\/lt.20906"},{"key":"bibr8-2150135119830089","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtcvs.2013.06.016"},{"key":"bibr9-2150135119830089","doi-asserted-by":"publisher","DOI":"10.1016\/j.athoracsur.2016.04.022"},{"key":"bibr10-2150135119830089","doi-asserted-by":"publisher","DOI":"10.1016\/j.athoracsur.2015.12.003"},{"key":"bibr11-2150135119830089","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.114.009120"},{"key":"bibr12-2150135119830089","doi-asserted-by":"publisher","DOI":"10.1016\/j.healun.2011.10.004"},{"key":"bibr13-2150135119830089","doi-asserted-by":"publisher","DOI":"10.1111\/petr.12149"}],"container-title":["World Journal for Pediatric and Congenital Heart Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/2150135119830089","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/2150135119830089","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/2150135119830089","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T23:22:15Z","timestamp":1777591335000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/2150135119830089"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,5]]},"references-count":13,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2019,5]]}},"alternative-id":["10.1177\/2150135119830089"],"URL":"https:\/\/doi.org\/10.1177\/2150135119830089","relation":{},"ISSN":["2150-1351","2150-136X"],"issn-type":[{"value":"2150-1351","type":"print"},{"value":"2150-136X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,5]]}}}