{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,21]],"date-time":"2026-08-21T22:45:43Z","timestamp":1787352343621,"version":"build-2736575974"},"reference-count":28,"publisher":"SAGE Publications","issue":"3","license":[{"start":{"date-parts":[[2019,5,1]],"date-time":"2019-05-01T00:00:00Z","timestamp":1556668800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"DOI":"10.13039\/100001130","name":"Gerber Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100001130","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["World J Pediatr Congenit Heart Surg"],"published-print":{"date-parts":[[2019,5]]},"abstract":"<jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>Pulmonary vascular supply in tetralogy of Fallot (TOF) with major aortopulmonary collaterals (MAPCAs) is highly variable. Our approach to surgical management of this condition emphasizes early repair including unifocalization and reconstruction of the pulmonary circulation, incorporating all lung segments and addressing stenoses both proximal to and within the lung, in addition to ventricular septal defect closure. At our institution, we have over 15 years of experience using lung perfusion scintigraphy (LPS) to assess the distribution of pulmonary blood flow after complete unifocalization and repair.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>We reviewed clinical and quantitative LPS data in 310 patients who underwent complete unifocalization and repair of TOF\/MAPCAs from 2003 to 2018 at our institution. Postrepair relative lung perfusion distributions were determined from LPS initially obtained at our institution within 60 days after repair and thereafter.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>Total lung perfusion to the right and left lungs was 58.0% \u00b1 14.2% and 42.0% \u00b1 14.2%, respectively. Perfusion was balanced in 75% of patients and unbalanced in 25%, including 11% in whom it was extremely unbalanced. On multivariable analysis, older age at repair, surgery other than a single-stage complete unifocalization, and native anatomy consisting of unilateral pulmonary blood supply through a ductus arteriosus were associated with unbalanced perfusion.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>We present our experience using LPS as an outcome measure after surgical repair of TOF\/MAPCAs. Balanced lung perfusion was present in the majority of patients who had complete repair of TOF\/MAPCAs performed at our center.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/2150135119836735","type":"journal-article","created":{"date-parts":[[2019,5,14]],"date-time":"2019-05-14T01:10:50Z","timestamp":1557796250000},"page":"313-320","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":10,"title":["Assessment of the Reconstructed Pulmonary Circulation With Lung Perfusion Scintigraphy After Unifocalization and Repair of Tetralogy of Fallot With Major Aortopulmonary Collaterals"],"prefix":"10.1177","volume":"10","author":[{"given":"Lisa","family":"Wise-Faberowski","sequence":"first","affiliation":[{"name":"Department of Anesthesiology, Lucile Packard Children\u2019s Hospital Children\u2019s Heart Center, Stanford University, Stanford, CA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matthew","family":"Irvin","sequence":"additional","affiliation":[{"name":"Clinical and Translational Research Program, Lucile Packard Children\u2019s Hospital Children\u2019s Heart Center, Stanford University, Stanford, CA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1069-538X","authenticated-orcid":false,"given":"Michael","family":"Lennig","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology, Lucile Packard Children\u2019s Hospital Children\u2019s Heart Center, Stanford University, Stanford, CA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jin","family":"Long","sequence":"additional","affiliation":[{"name":"Quantitative Sciences Unit, Department of Medicine, Lucile Packard Children\u2019s Hospital Children\u2019s Heart Center, Stanford University, Stanford, CA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Helen R.","family":"Nadel","sequence":"additional","affiliation":[{"name":"Department of Radiology, Lucile Packard Children\u2019s Hospital Children\u2019s Heart Center, Stanford University, Stanford, CA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Holly","family":"Bauser-Heaton","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Lucile Packard Children\u2019s Hospital Children\u2019s Heart Center, Stanford University, Stanford, CA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ritu","family":"Asija","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Lucile Packard Children\u2019s Hospital Children\u2019s Heart Center, Stanford University, Stanford, CA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Frank L.","family":"Hanley","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic Surgery, Lucile Packard Children\u2019s Hospital Children\u2019s Heart Center, Stanford University, Stanford, CA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Doff B.","family":"McElhinney","sequence":"additional","affiliation":[{"name":"Clinical and Translational Research Program, Lucile Packard Children\u2019s Hospital Children\u2019s Heart Center, Stanford University, Stanford, CA, USA"},{"name":"Department of Pediatrics, Lucile Packard Children\u2019s Hospital Children\u2019s Heart Center, Stanford University, Stanford, CA, USA"},{"name":"Department of Cardiothoracic Surgery, Lucile Packard Children\u2019s Hospital Children\u2019s Heart Center, Stanford University, Stanford, CA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2019,5,13]]},"reference":[{"key":"bibr1-2150135119836735","doi-asserted-by":"publisher","DOI":"10.1136\/hrt.34.4.418"},{"key":"bibr2-2150135119836735","doi-asserted-by":"publisher","DOI":"10.1017\/S1047951100000603"},{"key":"bibr3-2150135119836735","doi-asserted-by":"publisher","DOI":"10.1017\/S1047951100012981"},{"key":"bibr4-2150135119836735","doi-asserted-by":"publisher","DOI":"10.1016\/j.athoracsur.2016.03.011"},{"key":"bibr5-2150135119836735","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCINTERVENTIONS.116.004952"},{"key":"bibr6-2150135119836735","doi-asserted-by":"publisher","DOI":"10.1053\/j.pcsu.2009.01.017"},{"key":"bibr7-2150135119836735","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5223(95)70305-5"},{"key":"bibr8-2150135119836735","doi-asserted-by":"publisher","DOI":"10.1007\/s002469900312"},{"key":"bibr9-2150135119836735","doi-asserted-by":"publisher","DOI":"10.1017\/S1047951106000606"},{"key":"bibr10-2150135119836735","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtcvs.2009.08.011"},{"key":"bibr11-2150135119836735","doi-asserted-by":"publisher","DOI":"10.1017\/S1047951108003430"},{"key":"bibr12-2150135119836735","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5223(97)70076-X"},{"key":"bibr13-2150135119836735","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.101.15.1826"},{"key":"bibr14-2150135119836735","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtcvs.2010.07.087"},{"issue":"12","key":"bibr15-2150135119836735","first-page":"15N","volume":"57","author":"Treves ST","year":"2016","journal-title":"J Nucl Med"},{"key":"bibr16-2150135119836735","doi-asserted-by":"publisher","DOI":"10.1111\/j.1747-0803.2006.00037.x"},{"key":"bibr17-2150135119836735","doi-asserted-by":"publisher","DOI":"10.1016\/0003-4975(91)90452-V"},{"key":"bibr18-2150135119836735","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5223(03)00700-1"},{"key":"bibr19-2150135119836735","doi-asserted-by":"publisher","DOI":"10.1016\/j.athoracsur.2011.08.082"},{"key":"bibr20-2150135119836735","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5223(03)01200-5"},{"key":"bibr21-2150135119836735","doi-asserted-by":"publisher","DOI":"10.1097\/00003072-199606000-00009"},{"issue":"9","key":"bibr22-2150135119836735","first-page":"1477","volume":"40","author":"Pruckmayer M","year":"1999","journal-title":"J Nucl Med"},{"key":"bibr23-2150135119836735","doi-asserted-by":"publisher","DOI":"10.1016\/0735-1097(92)90495-9"},{"key":"bibr24-2150135119836735","doi-asserted-by":"publisher","DOI":"10.1007\/s12149-015-1029-8"},{"key":"bibr25-2150135119836735","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtcvs.2017.11.086"},{"key":"bibr26-2150135119836735","doi-asserted-by":"publisher","DOI":"10.1097\/RLU.0000000000002085"},{"key":"bibr27-2150135119836735","doi-asserted-by":"publisher","DOI":"10.1053\/j.semnuclmed.2018.10.006"},{"key":"bibr28-2150135119836735","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0187483"}],"container-title":["World Journal for Pediatric and Congenital Heart Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/2150135119836735","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/2150135119836735","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/2150135119836735","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T23:22:17Z","timestamp":1777591337000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/2150135119836735"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,5]]},"references-count":28,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2019,5]]}},"alternative-id":["10.1177\/2150135119836735"],"URL":"https:\/\/doi.org\/10.1177\/2150135119836735","relation":{},"ISSN":["2150-1351","2150-136X"],"issn-type":[{"value":"2150-1351","type":"print"},{"value":"2150-136X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,5]]}}}