{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,17]],"date-time":"2026-06-17T03:26:12Z","timestamp":1781666772110,"version":"3.54.5"},"reference-count":43,"publisher":"SAGE Publications","issue":"5","license":[{"start":{"date-parts":[[2019,9,1]],"date-time":"2019-09-01T00:00:00Z","timestamp":1567296000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["World J Pediatr Congenit Heart Surg"],"published-print":{"date-parts":[[2019,9]]},"abstract":"<jats:sec>\n                    <jats:title>Purpose:<\/jats:title>\n                    <jats:p>In transposition of great arteries, increased right ventricular (RV) afterload is observed following arterial switch operation (ASO), which is not always related to pulmonary artery (PA) stenosis. We hypothesize that abnormal PA bending from the Lecompte maneuver may affect RV afterload in the absence of stenosis. Thus, we sought to identify novel measurements of three-dimensional cardiac magnetic resonance (CMR) images of the pulmonary arteries and compare with conventional measurements in their ability to predict RV afterload.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>\n                      Conventional measurements and novel measurements of the pulmonary arteries were performed using CMR data from 42 ASO patients and 13 age-matched controls. Novel measurements included bending angle, normalized radius of curvature ( R\n                      <jats:sub>c<\/jats:sub>\n                      ), and normalized weighted radius of curvature ( R\n                      <jats:sub>c<\/jats:sub>\n                      <jats:sub>- w<\/jats:sub>\n                      ). Right ventricular systolic pressures (as the surrogate for RV afterload) were measured by either recent echocardiogram or cardiac catheterization.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      Conventional measurements of proximal PA size correlated with differential pulmonary blood flow ( r = 0.49, P = .001), but not with RV peak systolic pressures ( r = \u22120.26, P = .18). In ASO patients, R\n                      <jats:sub>c<\/jats:sub>\n                      <jats:sub>- w<\/jats:sub>\n                      correlated with higher RV systolic pressures ( r = \u22120.57, P = .002). Larger neoaortic areas and rightward bending angles correlated with smaller right pulmonary artery R\n                      <jats:sub>c<\/jats:sub>\n                      ( r = \u22120.48, P = .001; r = 0.41, P = .01, respectively). Finally, both pulmonary arteries had significantly smaller R\n                      <jats:sub>c<\/jats:sub>\n                      compared to normal controls.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>Pulmonary arteries exhibit abnormal bends following ASO that correlate with increased RV afterload, independent of PA stenosis. Future work should focus on clinical and hemodynamic contributions of these shape parameters.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/2150135119861358","type":"journal-article","created":{"date-parts":[[2019,9,9]],"date-time":"2019-09-09T08:00:38Z","timestamp":1568016038000},"page":"572-581","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":13,"title":["Abnormal Pulmonary Artery Bending Correlates With Increased Right Ventricular Afterload Following the Arterial Switch Operation"],"prefix":"10.1177","volume":"10","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1003-1903","authenticated-orcid":false,"given":"Yue-Hin","family":"Loke","sequence":"first","affiliation":[{"name":"Division of Cardiology, Children\u2019s National Medical Center, Washington, DC, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francesco","family":"Capuano","sequence":"additional","affiliation":[{"name":"Department of Industrial Engineering, Universita di Napoli Federico II, Naples, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jason","family":"Mandell","sequence":"additional","affiliation":[{"name":"Division of Cardiology, Children\u2019s National Medical Center, Washington, DC, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Russell R.","family":"Cross","sequence":"additional","affiliation":[{"name":"Division of Cardiology, Children\u2019s National Medical Center, Washington, DC, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ileen","family":"Cronin","sequence":"additional","affiliation":[{"name":"Division of Cardiology, Children\u2019s National Medical Center, Washington, DC, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paige","family":"Mass","sequence":"additional","affiliation":[{"name":"Sheikh Zayed Institute for Pediatric Surgical Innovation, Children\u2019s National Medical Center, Washington, DC, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elias","family":"Balaras","sequence":"additional","affiliation":[{"name":"Department of Mechanical and Aerospace Engineering, George Washington University, Washington, DC, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laura J.","family":"Olivieri","sequence":"additional","affiliation":[{"name":"Division of Cardiology, Children\u2019s National Medical Center, Washington, DC, USA"},{"name":"Sheikh Zayed Institute for Pediatric Surgical Innovation, Children\u2019s National Medical Center, Washington, DC, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2019,9,9]]},"reference":[{"key":"bibr1-2150135119861358","doi-asserted-by":"publisher","DOI":"10.1177\/2150135110376081"},{"key":"bibr2-2150135119861358","doi-asserted-by":"publisher","DOI":"10.1053\/j.pcsu.2016.10.002"},{"issue":"4","key":"bibr3-2150135119861358","first-page":"461","volume":"28","author":"Jatene AD","year":"1975","journal-title":"Arq Bras Cardiol"},{"key":"bibr4-2150135119861358","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.112.135046"},{"key":"bibr5-2150135119861358","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjcard.2009.04.029"},{"key":"bibr6-2150135119861358","doi-asserted-by":"publisher","DOI":"10.1136\/hrt.2006.109199"},{"key":"bibr7-2150135119861358","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtcvs.2013.07.048"},{"key":"bibr8-2150135119861358","doi-asserted-by":"publisher","DOI":"10.1093\/ehjci\/jew046"},{"key":"bibr9-2150135119861358","doi-asserted-by":"publisher","DOI":"10.1016\/j.athoracsur.2013.02.040"},{"key":"bibr10-2150135119861358","doi-asserted-by":"publisher","DOI":"10.1007\/s004310050777"},{"key":"bibr11-2150135119861358","doi-asserted-by":"publisher","DOI":"10.1055\/s-2004-820881"},{"key":"bibr12-2150135119861358","doi-asserted-by":"publisher","DOI":"10.1007\/s00330-013-2998-4"},{"key":"bibr13-2150135119861358","doi-asserted-by":"publisher","DOI":"10.1115\/1.4043034"},{"key":"bibr14-2150135119861358","doi-asserted-by":"publisher","DOI":"10.1093\/icvts\/ivw014"},{"key":"bibr15-2150135119861358","doi-asserted-by":"publisher","DOI":"10.1002\/9780470994849.ch16"},{"key":"bibr16-2150135119861358","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.fl.15.010183.002333"},{"key":"bibr17-2150135119861358","volume-title":"Natl Sci Found","author":"Idel\u2019Chik IE"},{"key":"bibr18-2150135119861358","doi-asserted-by":"publisher","DOI":"10.1007\/s10554-010-9672-6"},{"key":"bibr19-2150135119861358","doi-asserted-by":"publisher","DOI":"10.1186\/1532-429X-10-56"},{"key":"bibr20-2150135119861358","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5223(19)38300-X"},{"key":"bibr21-2150135119861358","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcmg.2011.02.011"},{"key":"bibr22-2150135119861358","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijcard.2013.06.019"},{"key":"bibr23-2150135119861358","doi-asserted-by":"publisher","DOI":"10.1007\/s00247-014-2944-x"},{"issue":"2","key":"bibr24-2150135119861358","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1007\/BF00817606","volume":"15","author":"Sam\u00e1nek M","year":"1994","journal-title":"Pediatr Cardiol"},{"key":"bibr25-2150135119861358","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCIMAGING.116.004618"},{"key":"bibr26-2150135119861358","doi-asserted-by":"publisher","DOI":"10.1159\/000099052"},{"key":"bibr27-2150135119861358","doi-asserted-by":"publisher","DOI":"10.1007\/s00246-016-1412-9"},{"key":"bibr28-2150135119861358","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehr461"},{"key":"bibr29-2150135119861358","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjcard.2009.05.046"},{"key":"bibr30-2150135119861358","doi-asserted-by":"publisher","DOI":"10.1111\/chd.12303"},{"key":"bibr31-2150135119861358","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjcard.2010.05.035"},{"key":"bibr32-2150135119861358","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtcvs.2015.07.101"},{"key":"bibr33-2150135119861358","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2013.10.027"},{"key":"bibr34-2150135119861358","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2018.12.076"},{"key":"bibr35-2150135119861358","doi-asserted-by":"publisher","DOI":"10.1111\/chd.12250"},{"key":"bibr36-2150135119861358","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtcvs.2017.05.002"},{"key":"bibr37-2150135119861358","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtcvs.2016.09.018"},{"key":"bibr38-2150135119861358","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtcvs.2017.04.016"},{"key":"bibr39-2150135119861358","doi-asserted-by":"publisher","DOI":"10.1007\/s00246-018-1833-8"},{"key":"bibr40-2150135119861358","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1522-726X(200006)50:2<207::AID-CCD14>3.0.CO;2-U"},{"key":"bibr41-2150135119861358","doi-asserted-by":"publisher","DOI":"10.1093\/ejcts\/ezy178"},{"key":"bibr42-2150135119861358","doi-asserted-by":"publisher","DOI":"10.1007\/s00246-018-1924-6"},{"key":"bibr43-2150135119861358","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejcts.2009.12.032"}],"container-title":["World Journal for Pediatric and Congenital Heart Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/2150135119861358","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/2150135119861358","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/2150135119861358","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T23:22:33Z","timestamp":1777591353000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/2150135119861358"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,9]]},"references-count":43,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2019,9]]}},"alternative-id":["10.1177\/2150135119861358"],"URL":"https:\/\/doi.org\/10.1177\/2150135119861358","relation":{},"ISSN":["2150-1351","2150-136X"],"issn-type":[{"value":"2150-1351","type":"print"},{"value":"2150-136X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,9]]}}}