{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,21]],"date-time":"2026-08-21T22:45:43Z","timestamp":1787352343642,"version":"build-2736575974"},"reference-count":40,"publisher":"SAGE Publications","issue":"2","license":[{"start":{"date-parts":[[2020,2,25]],"date-time":"2020-02-25T00:00:00Z","timestamp":1582588800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"DOI":"10.13039\/100001130","name":"The Gerber Foundation","doi-asserted-by":"crossref","id":[{"id":"10.13039\/100001130","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["World J Pediatr Congenit Heart Surg"],"published-print":{"date-parts":[[2020,3]]},"abstract":"<jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>Surgical repair of tetralogy of Fallot and major aortopulmonary collaterals (TOF\/MAPCAs) involves unifocalization of MAPCAs and reconstruction of the pulmonary arterial circulation. Surgical and cardiopulmonary bypass (CPB) times are long and suture lines are extensive. Maintaining patency of the newly anastomosed vessels while achieving hemostasis is important, and assessment of transfusion practices is critical to successful outcomes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>Clinical, surgical, and transfusion data in patients with TOF\/MAPCAs repaired at our institution (2013-2018) were reviewed. Types and volumes of blood products used in the perioperative period, in addition to the use of antifibrinolytics and\/or procoagulants (factor VIII inhibitor bypassing activity [FEIBA]; anti-inhibitor coagulant complex), were assessed. Outcome measures included days on mechanical ventilation (DOMV), postoperative intensive care unit and hospital length of stay (LoS), and incidence of thrombosis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>Perioperative transfusion data from 279 patients were analyzed. Surgical (879 \u00b1 175 minutes vs 684 \u00b1 257 minutes) and CPB times (376 \u00b1 124 minutes vs 234 \u00b1 122 minutes) were longer in patients who received FEIBA than those who did not. Although the indexed volume of packed red blood cells (128.4 \u00b1 82.2 mL\/kg) and fresh frozen plasma (64.2 \u00b1 41.1 mL\/kg) was similar in patients who did and did not receive FEIBA, the amounts of cryoprecipitate (5.5 \u00b1 5.2 mL\/kg vs 5.8 \u00b1 4.8 mL\/kg) and platelets (19.5 \u00b1 20.7 mL\/kg vs 20.8 \u00b1 13 mL\/kg) transfused were more in those who did receive FEIBA.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>Perioperative transfusion is an important component in the overall surgical and anesthetic management of patients with TOF\/MAPCAs. The intraoperative use of FEIBA was not associated with a decrease in the amount of blood products transfused, DOMV, or LoS or with an increase in thrombotic complications.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/2150135119892192","type":"journal-article","created":{"date-parts":[[2020,2,25]],"date-time":"2020-02-25T05:03:02Z","timestamp":1582606982000},"page":"159-165","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":6,"title":["Transfusion Outcomes in Patients Undergoing Unifocalization and Repair of Tetralogy of Fallot With Major Aortopulmonary Collaterals"],"prefix":"10.1177","volume":"11","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5876-5311","authenticated-orcid":false,"given":"Lisa","family":"Wise-Faberowski","sequence":"first","affiliation":[{"name":"Department of Anesthesiology, Lucile Packard Children\u2019s Hospital Heart Center, Stanford University, Stanford, CA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matthew","family":"Irvin","sequence":"additional","affiliation":[{"name":"Clinical and Translational Research Program, Lucile Packard Children\u2019s Hospital Heart Center, Stanford University, Stanford, CA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zoel A.","family":"Quinonez","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology, Lucile Packard Children\u2019s Hospital Heart Center, Stanford University, Stanford, CA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jin","family":"Long","sequence":"additional","affiliation":[{"name":"Quantitative Sciences Unit, Department of Medicine, Lucile Packard Children\u2019s Hospital Heart Center, Stanford University, Stanford, CA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ritu","family":"Asija","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Lucile Packard Children\u2019s Hospital Heart Center, Stanford University, Stanford, CA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tristan D.","family":"Margetson","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic Surgery, Lucile Packard Children\u2019s Hospital Heart Center, Stanford University, Stanford, CA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Frank L.","family":"Hanley","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic Surgery, Lucile Packard Children\u2019s Hospital Heart Center, Stanford University, Stanford, CA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Doff B.","family":"McElhinney","sequence":"additional","affiliation":[{"name":"Clinical and Translational Research Program, Lucile Packard Children\u2019s Hospital Heart Center, Stanford University, Stanford, CA, USA"},{"name":"Department of Pediatrics, Lucile Packard Children\u2019s Hospital Heart Center, Stanford University, Stanford, CA, USA"},{"name":"Department of Cardiothoracic Surgery, Lucile Packard Children\u2019s Hospital Heart Center, Stanford University, Stanford, CA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2020,2,25]]},"reference":[{"key":"bibr1-2150135119892192","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCINTERVENTIONS.116.004952"},{"key":"bibr2-2150135119892192","doi-asserted-by":"publisher","DOI":"10.1053\/j.pcsu.2009.01.017"},{"key":"bibr3-2150135119892192","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.101.15.1826"},{"key":"bibr4-2150135119892192","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtcvs.2010.07.087"},{"key":"bibr5-2150135119892192","doi-asserted-by":"publisher","DOI":"10.1177\/2150135118754522"},{"key":"bibr6-2150135119892192","doi-asserted-by":"publisher","DOI":"10.1053\/j.jvca.2017.04.039"},{"key":"bibr7-2150135119892192","doi-asserted-by":"publisher","DOI":"10.1093\/ejcts\/ezt548"},{"key":"bibr8-2150135119892192","doi-asserted-by":"publisher","DOI":"10.1016\/j.athoracsur.2010.07.037"},{"issue":"2","key":"bibr9-2150135119892192","first-page":"CD009752","author":"Wilkinson KL","year":"2014","journal-title":"Cochrane Database Syst Rev"},{"key":"bibr10-2150135119892192","doi-asserted-by":"publisher","DOI":"10.1111\/j.1460-9592.2010.03464.x"},{"key":"bibr11-2150135119892192","doi-asserted-by":"publisher","DOI":"10.1097\/PCC.0b013e3181e30d43"},{"key":"bibr12-2150135119892192","doi-asserted-by":"publisher","DOI":"10.1016\/S1053-0770(99)90268-9"},{"key":"bibr13-2150135119892192","doi-asserted-by":"publisher","DOI":"10.1111\/pan.13533"},{"key":"bibr14-2150135119892192","unstructured":"Feiba [package insert]. 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