{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T07:09:37Z","timestamp":1777878577108,"version":"3.51.4"},"reference-count":8,"publisher":"SAGE Publications","issue":"4","license":[{"start":{"date-parts":[[2020,7,1]],"date-time":"2020-07-01T00:00:00Z","timestamp":1593561600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["World J Pediatr Congenit Heart Surg"],"published-print":{"date-parts":[[2020,7]]},"abstract":"<jats:p>Congenital diaphragmatic hernia (CDH) is a rare disease, which affects 1 in 2,500 newborns. Congenital diaphragmatic hernia can interfere with the normal development of the pulmonary parenchyma and vascular bed, and in severe cases, it can lead to the development of severe pulmonary arterial hypertension (PAH) and right ventricular failure. We present a neonate with CDH who developed severe PAH and right ventricular dysfunction and was managed with a unique strategy combining venoarterial extracorporeal membrane oxygenation, prostaglandin E1, and a variety of PAH therapies.<\/jats:p>","DOI":"10.1177\/2150135120912678","type":"journal-article","created":{"date-parts":[[2020,7,7]],"date-time":"2020-07-07T06:11:03Z","timestamp":1594102263000},"page":"525-527","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":2,"title":["Combination of PGE1 and Pulmonary Vasodilator Therapy in Managing a Challenging Case of Severe PAH Secondary to CDH"],"prefix":"10.1177","volume":"11","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8195-3799","authenticated-orcid":false,"given":"Othman A.","family":"Aljohani","sequence":"first","affiliation":[{"name":"Division of Pediatric Cardiology, Department of Pediatrics, Rady Children\u2019s Hospital, San Diego, CA, USA"},{"name":"University of California, San Diego, CA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rohit","family":"Rao","sequence":"additional","affiliation":[{"name":"Division of Pediatric Cardiology, Department of Pediatrics, Rady Children\u2019s Hospital, San Diego, CA, USA"},{"name":"University of California, San Diego, CA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Duncan","family":"Mackie","sequence":"additional","affiliation":[{"name":"University of California San Diego School of Medicine, CA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shylah","family":"Haldeman","sequence":"additional","affiliation":[{"name":"Division of Pediatric Cardiology, Department of Pediatrics, Rady Children\u2019s Hospital, San Diego, CA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tara","family":"Karamlou","sequence":"additional","affiliation":[{"name":"Division of Pediatric Cardiac Surgery and the Heart Vascular Institute, Cleveland Clinic, OH, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2020,7,7]]},"reference":[{"key":"bibr1-2150135120912678","doi-asserted-by":"publisher","DOI":"10.1053\/j.sempedsurg.2007.01.008"},{"key":"bibr2-2150135120912678","doi-asserted-by":"publisher","DOI":"10.1161\/CIR.0000000000000329"},{"key":"bibr3-2150135120912678","doi-asserted-by":"publisher","DOI":"10.1016\/j.athoracsur.2010.04.007"},{"key":"bibr4-2150135120912678","doi-asserted-by":"publisher","DOI":"10.1213\/01.ane.0000255732.16057.1c"},{"key":"bibr5-2150135120912678","first-page":"Cd011417","volume":"2","author":"Akkinapally S","year":"2018","journal-title":"Cochrane Database Syst Rev"},{"key":"bibr6-2150135120912678","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199208203270801"},{"key":"bibr7-2150135120912678","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpedsurg.2018.10.039"},{"key":"bibr8-2150135120912678","doi-asserted-by":"publisher","DOI":"10.1002\/pd.3890"}],"container-title":["World Journal for Pediatric and Congenital Heart Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/2150135120912678","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/2150135120912678","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/2150135120912678","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T23:23:08Z","timestamp":1777591388000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/2150135120912678"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,7]]},"references-count":8,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2020,7]]}},"alternative-id":["10.1177\/2150135120912678"],"URL":"https:\/\/doi.org\/10.1177\/2150135120912678","relation":{},"ISSN":["2150-1351","2150-136X"],"issn-type":[{"value":"2150-1351","type":"print"},{"value":"2150-136X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,7]]}}}