{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,5]],"date-time":"2026-08-05T05:12:09Z","timestamp":1785906729620,"version":"3.56.0"},"reference-count":26,"publisher":"SAGE Publications","issue":"2","license":[{"start":{"date-parts":[[2021,3,1]],"date-time":"2021-03-01T00:00:00Z","timestamp":1614556800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"name":"The Vivienne and Ross Hobson Trust"},{"name":"The Wishaw Family Trust"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["World J Pediatr Congenit Heart Surg"],"published-print":{"date-parts":[[2021,3]]},"abstract":"<jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>We sought to evaluate the outcomes following right ventricle to pulmonary artery (RV-PA) conduit placement in pediatric patients, excluding those with a RV-PA conduit for the Ross procedure which is associated with improved conduit durability, partly related to its orthotopic position.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>Outcomes for 119 patients who underwent RV-PA conduit placement at a single institution from January 2004 to December 2016 were reviewed. Primary outcome measures were reintervention-free survival (RFS) and overall survival. Survival analyses were performed using the Kaplan-Meier method, and risk factors associated with reintervention were evaluated.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>The median age at the time of conduit placement was 6 months (interquartile range, IQR: 1-14), and the median length of follow-up was 63 months (range: 0-156). During follow-up, 39 patients required conduit-related reintervention, while 6 patients died perioperatively with an overall survival of 90% at 10 years. Among the remaining 113 patients, the RFS at one, five, and ten years was 91% (84%-95%), 72% (60%-80%), and 33% (16%-50%), respectively. The median time to conduit replacement in the series was 43.5 months (IQR: 19.3-76.2). The use of a pulmonary homograft was associated with improved RFS ( P = .03), and this was particularly pronounced in comparison with aortic homografts in neonates. Infection was the indication for replacement in only one patient.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>The majority of the conduits placed during the neonatal period required conduit replacement before the age of five years. Endocarditis was not a common indication for replacement. In neonates and infants, we prefer pulmonary homografts for most indications.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/2150135120975769","type":"journal-article","created":{"date-parts":[[2021,3,8]],"date-time":"2021-03-08T12:43:41Z","timestamp":1615207421000},"page":"220-229","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":15,"title":["Outcomes Following Heterotopic Placement of Right Ventricle to Pulmonary Artery Conduits"],"prefix":"10.1177","volume":"12","author":[{"given":"Akshat","family":"Saxena","sequence":"first","affiliation":[{"name":"Heart Centre for Children, The Children\u2019s Hospital at Westmead, New South Wales, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gananjay G.","family":"Salve","sequence":"additional","affiliation":[{"name":"Heart Centre for Children, The Children\u2019s Hospital at Westmead, New South Wales, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kim","family":"Betts","sequence":"additional","affiliation":[{"name":"School of Public Health, Curtin University, Perth, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nitin","family":"Arora","sequence":"additional","affiliation":[{"name":"Heart Centre for Children, The Children\u2019s Hospital at Westmead, New South Wales, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrew D.","family":"Cole","sequence":"additional","affiliation":[{"name":"Heart Centre for Children, The Children\u2019s Hospital at Westmead, New South Wales, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gary F.","family":"Sholler","sequence":"additional","affiliation":[{"name":"Heart Centre for Children, The Children\u2019s Hospital at Westmead, New South Wales, Australia"},{"name":"School of Child and Adolescent Health, Sydney Medical School, Faculty of Medicine and Health, University of Sydney, New South Wales, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yishay","family":"Orr","sequence":"additional","affiliation":[{"name":"Heart Centre for Children, The Children\u2019s Hospital at Westmead, New South Wales, Australia"},{"name":"School of Child and Adolescent Health, Sydney Medical School, Faculty of Medicine and Health, University of Sydney, New South Wales, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julian G.","family":"Ayer","sequence":"additional","affiliation":[{"name":"Heart Centre for Children, The Children\u2019s Hospital at Westmead, New South Wales, Australia"},{"name":"School of Child and Adolescent Health, Sydney Medical School, Faculty of Medicine and Health, University of Sydney, New South Wales, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8005-3361","authenticated-orcid":false,"given":"David 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