{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,29]],"date-time":"2026-10-29T20:16:22Z","timestamp":1793304982238,"version":"4.5.0"},"reference-count":16,"publisher":"SAGE Publications","issue":"2","license":[{"start":{"date-parts":[[2021,3,1]],"date-time":"2021-03-01T00:00:00Z","timestamp":1614556800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["World J Pediatr Congenit Heart Surg"],"published-print":{"date-parts":[[2021,3]]},"abstract":"<jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>Anomalous aortic origin of a coronary artery (AAOCA) is associated with sudden death in the young. We sought to determine quality of life (QOL) in patients\/families affected by AAOCA.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>Patients with AAOCA (8-18 years) were prospectively included from January 2016 to May 2017. Parent proxy and patient Pediatric Cardiac Quality of Life Inventory (PCQLI) were used to evaluate QOL and Pediatric Quality of Life Inventory (PedsQL) Family Impact Module to assess the impact of AAOCA on families, as primary outcomes. Secondary outcomes included peer relationship, anxiety, and depression assessed using patient-reported outcomes measurement information system. Patients deemed high-risk were offered surgery\/exercise restriction. Generalized linear mixed regression models were used to determine significant predictors of outcomes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>Fifty-three patients, the majority (n = 31, 59%) unrepaired, and 49 caregivers were included. Using PCQLI, patient and parent proxy QOL scores were similar to published scores for children with long-QT syndrome. Patients\u2019 QOL score was associated with exertional symptoms, perceived chronic disease, and altered parent\u2019s concentration ability. Likewise, parent proxy QOL scores were associated with mother\u2019s living situation, exertional symptoms, parent missing work for \u22651 day, and disturbed parental functioning at work. Family impact scores were associated with lower maternal education, among other measures. Risk categories or surgical status did not impact patient, parent proxy reported, or family impact QOL.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>Anomalous aortic origin of a coronary artery is associated with decreased QOL as perceived by patients and caregiver and is associated with numerous facets of family functioning. These findings are independent of risk categorization or surgical status.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/2150135120978766","type":"journal-article","created":{"date-parts":[[2021,3,8]],"date-time":"2021-03-08T12:43:41Z","timestamp":1615207421000},"page":"204-210","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":15,"title":["Decreased Quality of Life in Children With Anomalous Aortic Origin of a Coronary Artery"],"prefix":"10.1177","volume":"12","author":[{"given":"Hitesh","family":"Agrawal","sequence":"first","affiliation":[{"name":"Pediatric and Congenital Cardiology Associates, The University of Texas at Austin Dell Medical School, Austin, TX"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carlos M.","family":"Mery","sequence":"additional","affiliation":[{"name":"Texas Center for Pediatric and Congenital Heart Disease, University of Texas Dell Medical School\/Dell Children\u2019s Medical Center, Austin, TX, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sarah A.","family":"Sami","sequence":"additional","affiliation":[{"name":"Baylor College of Medicine, Office of Surgical Research, Houston, TX, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Athar M.","family":"Qureshi","sequence":"additional","affiliation":[{"name":"Coronary Anomalies Program, The Lillie Frank Abercrombie Section of Pediatric Cardiology, Texas Children\u2019s Hospital, Baylor College of Medicine, Houston, TX, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cory V.","family":"Noel","sequence":"additional","affiliation":[{"name":"Coronary Anomalies Program, The Lillie Frank Abercrombie Section of Pediatric Cardiology, Texas Children\u2019s Hospital, Baylor College of Medicine, Houston, TX, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katherine","family":"Cutitta","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Section of Psychology, Texas Children\u2019s Hospital, Baylor College of Medicine, Houston, TX, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Prakash","family":"Masand","sequence":"additional","affiliation":[{"name":"Pediatric Radiology, Texas Children\u2019s Hospital, Houston, TX, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S. Kristen Sexson","family":"Tejtel","sequence":"additional","affiliation":[{"name":"Coronary Anomalies Program, The Lillie Frank Abercrombie Section of Pediatric Cardiology, Texas Children\u2019s Hospital, Baylor College of Medicine, Houston, TX, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yunfei","family":"Wang","sequence":"additional","affiliation":[{"name":"The Lillie Frank Abercrombie Section of Pediatric Cardiology, Texas Children\u2019s Hospital, Baylor College of Medicine, Houston, TX, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Silvana","family":"Molossi","sequence":"additional","affiliation":[{"name":"Coronary Anomalies Program, The Lillie Frank Abercrombie Section of Pediatric Cardiology, Texas Children\u2019s Hospital, Baylor College of Medicine, Houston, TX, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2021,3,8]]},"reference":[{"key":"bibr1-2150135120978766","doi-asserted-by":"publisher","DOI":"10.1053\/j.semtcvs.2014.08.001"},{"key":"bibr2-2150135120978766","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.108.804617"},{"key":"bibr3-2150135120978766","doi-asserted-by":"publisher","DOI":"10.1111\/chd.12511"},{"key":"bibr4-2150135120978766","doi-asserted-by":"publisher","DOI":"10.1111\/chd.12473"},{"issue":"5","key":"bibr5-2150135120978766","first-page":"1","volume":"27","author":"Sing AC","year":"2016","journal-title":"Cardiol Young"},{"key":"bibr6-2150135120978766","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtcvs.2008.08.008"},{"key":"bibr7-2150135120978766","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCINTERVENTIONS.119.008445"},{"key":"bibr8-2150135120978766","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2009-2973"},{"key":"bibr9-2150135120978766","doi-asserted-by":"publisher","DOI":"10.1186\/1477-7525-2-55"},{"key":"bibr10-2150135120978766","unstructured":"Patient reported outcomes measurement information system, scoring manuals. 2015. Accessed April 25, 2017. http:\/\/www.healthmeasures.net\/explore-measurement-systems\/promis"},{"key":"bibr11-2150135120978766","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjcard.2015.11.051"},{"key":"bibr12-2150135120978766","doi-asserted-by":"publisher","DOI":"10.1111\/jpc.13445"},{"issue":"3","key":"bibr13-2150135120978766","first-page":"e42006","volume":"95","author":"Hsieh R-L","year":"2016","journal-title":"Medicine"},{"key":"bibr14-2150135120978766","doi-asserted-by":"publisher","DOI":"10.1007\/s11136-015-0953-3"},{"key":"bibr15-2150135120978766","doi-asserted-by":"publisher","DOI":"10.1007\/s11136-015-1058-8"},{"key":"bibr16-2150135120978766","doi-asserted-by":"publisher","DOI":"10.1016\/j.jclinepi.2015.08.036"}],"container-title":["World Journal for Pediatric and Congenital Heart Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/2150135120978766","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/2150135120978766","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/2150135120978766","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T23:23:40Z","timestamp":1777591420000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/2150135120978766"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,3]]},"references-count":16,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2021,3]]}},"alternative-id":["10.1177\/2150135120978766"],"URL":"https:\/\/doi.org\/10.1177\/2150135120978766","relation":{},"ISSN":["2150-1351","2150-136X"],"issn-type":[{"value":"2150-1351","type":"print"},{"value":"2150-136X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,3]]}}}