{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T02:16:29Z","timestamp":1787019389114,"version":"build-2736575974"},"reference-count":20,"publisher":"SAGE Publications","issue":"6","license":[{"start":{"date-parts":[[2021,11,1]],"date-time":"2021-11-01T00:00:00Z","timestamp":1635724800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["World J Pediatr Congenit Heart Surg"],"published-print":{"date-parts":[[2021,11]]},"abstract":"<jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>We reviewed our center's prenatal detection and surgical experience with high-risk, 2-ventricle patients, with complex congenital heart disease that underwent stage-1 hybrid palliation.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We retrospectively identified those born between March 2008 and March 2021 with 2-ventricle hearts, complex congenital cardiovascular malformations, and ductal-dependent systemic circulation that underwent stage-1 hybrid palliation consisting of surgical bilateral pulmonary artery banding and interventional catheterization placed ductus arteriosus stents.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>We identified 30 patients. Of the 30, 19 (63%) were male. For the 30, median gestational age was 35 weeks (29-39 weeks), and median birth weight was 2.2\u2005kg (0.6-4.5\u2005kg). Of the 30, 1 was transferred from an adjacent state, and 29 were born in Nevada. Of the 29 born in Nevada, overall statewide prenatal detection was 18 of 29 (62%); however, for 2008 to 2011 the prenatal detection rate was 3 of 10 (30%) and 15 of 19 (79%) for 2012 to 2021, P\u2009=\u2009.03. For the last 5 years, prenatal detection for Nevada-born patients was 8 of 8 (100%). Two full-term newborns, without a prenatal diagnosis, presented postnatally in extremis. For the 30 patients, there were 0 stage-1 hybrid palliation mortalities, 1 subsequent repair mortality, and 3 late nonsurgical deaths.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Stage-1 hybrid palliation may result in excellent surgical outcomes for high-risk, 2-ventricle patients. Additionally, high rates of population-wide prenatal detection are possible for high-risk congenital heart disease, allowing prenatal planning and possibly reducing postnatal extremis presentations.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/21501351211044417","type":"journal-article","created":{"date-parts":[[2021,11,30]],"date-time":"2021-11-30T17:33:02Z","timestamp":1638293582000},"page":"754-759","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":4,"title":["Stage-1 Hybrid Palliation for High-Risk 2-Ventricle Patients with Ductal-Dependent Systemic Circulation  in the Era of High Prenatal Detection"],"prefix":"10.1177","volume":"12","author":[{"given":"William N.","family":"Evans","sequence":"first","affiliation":[{"name":"Congenital Heart Center Nevada, Las Vegas, NV, USA"},{"name":"Kirk Kerkorian School of Medicine at University of Nevada Las Vegas, Las Vegas, NV, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ruben J.","family":"Acherman","sequence":"additional","affiliation":[{"name":"Congenital Heart Center Nevada, Las Vegas, NV, USA"},{"name":"Kirk Kerkorian School of Medicine at University of Nevada Las Vegas, Las Vegas, NV, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael L.","family":"Ciccolo","sequence":"additional","affiliation":[{"name":"Congenital Heart Center Nevada, Las Vegas, NV, USA"},{"name":"Kirk Kerkorian School of Medicine at University of Nevada Las Vegas, Las Vegas, NV, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juan","family":"Lehoux","sequence":"additional","affiliation":[{"name":"Congenital Heart Center Nevada, Las Vegas, NV, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alvaro","family":"Galindo","sequence":"additional","affiliation":[{"name":"Congenital Heart Center Nevada, Las Vegas, NV, USA"},{"name":"Kirk Kerkorian School of Medicine at University of Nevada Las Vegas, Las Vegas, NV, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abraham","family":"Rothman","sequence":"additional","affiliation":[{"name":"Congenital Heart Center Nevada, Las Vegas, NV, USA"},{"name":"Kirk Kerkorian School of Medicine at University of Nevada Las Vegas, Las Vegas, NV, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gary A.","family":"Mayman","sequence":"additional","affiliation":[{"name":"Congenital Heart Center Nevada, Las Vegas, NV, USA"},{"name":"Kirk Kerkorian School of Medicine at University of Nevada Las Vegas, Las Vegas, NV, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1198-5787","authenticated-orcid":false,"given":"Humberto","family":"Restrepo","sequence":"additional","affiliation":[{"name":"Congenital Heart Center Nevada, Las Vegas, NV, USA"},{"name":"Kirk Kerkorian School of Medicine at University of Nevada Las 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