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This meta-analysis, which includes 44 total studies consisting of 1857 patients, compares mortality at different time points (operative, in-hospital, and post-discharge), reoperation rates, and postoperative ventricular dysfunction between these two categories of procedures. Although anatomic and physiologic repair had similar operative and in-hospital mortality, anatomic repair patients had significantly less post-discharge mortality (6.1% vs 9.7%; P\u2009=\u2009.006), lower reoperation rates (17.9% vs 20.6%; P\u2009&lt;\u2009.001), and less postoperative ventricular dysfunction (16% vs 43%; P\u2009&lt;\u2009.001). When anatomic repair patients were subdivided into those who had atrial and arterial switch versus those who had atrial switch with Rastelli, the double switch group had significantly lower in-hospital mortality (4.3% vs 7.6%; P\u2009=\u2009.026) and reoperation rates (15.6% vs 25.9%; P\u2009&lt;\u2009.001). The results of this meta-analysis suggest a protective benefit of favoring anatomic repair over physiologic repair.<\/jats:p>","DOI":"10.1177\/21501351221127894","type":"journal-article","created":{"date-parts":[[2023,2,27]],"date-time":"2023-02-27T10:45:40Z","timestamp":1677494740000},"page":"70-76","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":10,"title":["Outcomes After Anatomic Versus Physiologic Repair of Congenitally Corrected Transposition of the Great Arteries: A Systematic Review and Meta-Analysis"],"prefix":"10.1177","volume":"14","author":[{"given":"Isao","family":"Anzai","sequence":"first","affiliation":[{"name":"Department of Surgery, Division of Cardiac, Thoracic, and Vascular Surgery, Section of Pediatric and Congenital Cardiac Surgery, New-York Presbyterian - Morgan Stanley Children's Hospital, Columbia University Medical Center, New York, NY, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yanling","family":"Zhao","sequence":"additional","affiliation":[{"name":"Department of Surgery, Division of Cardiac, Thoracic, and Vascular Surgery, Section of Pediatric and Congenital Cardiac Surgery, New-York Presbyterian - Morgan Stanley Children's Hospital, Columbia University Medical Center, New York, NY, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arnaldo","family":"Dimagli","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic Surgery, Weill Cornell Medicine, New York, NY, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christian","family":"Pearsall","sequence":"additional","affiliation":[{"name":"Columbia University Vagelos College of Physicians and Surgeons, New York, NY, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9673-904X","authenticated-orcid":false,"given":"Marian","family":"LaForest","sequence":"additional","affiliation":[{"name":"Augustus C. 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