{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T15:37:15Z","timestamp":1790350635407,"version":"4.1.0"},"reference-count":28,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[2023,8,7]],"date-time":"2023-08-07T00:00:00Z","timestamp":1691366400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["World J Pediatr Congenit Heart Surg"],"published-print":{"date-parts":[[2024,1]]},"abstract":"<jats:p>Background: National data about the outcomes of children undergoing mechanical mitral valve replacement (m-MVR) are scarce. Methods: A retrospective review of hospitalizations from the Kids\u2019 Inpatient Database was performed for patients \u226418 years of age in the United States. A total of 500 patients underwent m-MVR in 2009, 2012, 2016, and 2019. Patients with single ventricle physiology were excluded (n\u2009\u2009=\u2009\u200913). These patients were categorized into three groups according to age: neonates (&lt;1 month, n\u2009\u2009=\u2009\u200920), infants (1-12 months, n\u2009\u2009=\u2009\u200976 patients), and children (1-18 years, n\u2009\u2009=\u2009\u2009404). Outcomes were compared between the three groups. Results: The proportion of m-MVR involving children undergoing MV procedures (repair and replacement) has increased from 17.3% in 2009 to 30.8% in 2019 (Ptrend &lt; .01). History of cardiac surgery was present in 256 patients (51.2%). Concomitant procedures were performed in 119 patients (23.8%). Intra- or postoperative extracorporeal membrane oxygenation was required in 19 patients (3.8%). The overall in-hospital mortality was 4.8% and was significantly higher in neonates and infants compared with older children (10% vs 11.8% vs 3.2%, P\u2009=\u2009.003). The length of hospital stay was longer in the neonatal group (median, 57 days, interquartile range, [24.8-90] vs 29.5 days [15.5-61] vs 10 days [7-18], P\u2009&lt;\u2009.01). Nonhome discharges were more common in neonates and infants (40% vs 36.8% vs 13.1%, P\u2009&lt;\u2009.01). Conclusion: Mechanical mitral valve replacement is increasingly performed over time with acceptable in-hospital morbidity and mortality, especially in older children and adolescents. Neonates and infants are associated with worse hospital survival, prolonged hospitalization, and significant rates of nonhome discharges.<\/jats:p>","DOI":"10.1177\/21501351231185118","type":"journal-article","created":{"date-parts":[[2023,8,8]],"date-time":"2023-08-08T02:29:46Z","timestamp":1691461786000},"page":"37-43","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":4,"title":["National In-Hospital Outcomes of Mechanical Mitral Valve Replacement in the Pediatric Population"],"prefix":"10.1177","volume":"15","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8184-9203","authenticated-orcid":false,"given":"Mohamed F.","family":"Elsisy","sequence":"first","affiliation":[{"name":"Department of Cardiovascular Surgery, Mayo Clinic, Rochester, MN, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2664-1290","authenticated-orcid":false,"given":"Joseph A.","family":"Dearani","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Surgery, Mayo Clinic, Rochester, MN, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elena","family":"Ashikhmina","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology and Perioperative Medicine, Mayo Clinic, Rochester, MN, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Devon O.","family":"Aganga","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology and Perioperative Medicine, Mayo Clinic, Rochester, MN, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7424-8207","authenticated-orcid":false,"given":"Nathaniel W.","family":"Taggart","sequence":"additional","affiliation":[{"name":"Division of Pediatric Cardiology, Department of Pediatric and Adolescent Medicine, Mayo Clinic, Rochester, MN, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Austin","family":"Todd","sequence":"additional","affiliation":[{"name":"Division of Clinical Trials and Biostatistics, Department of Quantitative Health Services, Mayo Clinic, Rochester, MN, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elizabeth H.","family":"Stephens","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Surgery, Mayo Clinic, Rochester, MN, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2023,8,7]]},"reference":[{"key":"bibr1-21501351231185118","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtcvs.2007.04.025"},{"key":"bibr2-21501351231185118","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejcts.2007.02.006"},{"key":"bibr3-21501351231185118","doi-asserted-by":"publisher","DOI":"10.1016\/j.athoracsur.2010.06.121"},{"key":"bibr4-21501351231185118","doi-asserted-by":"publisher","DOI":"10.4103\/0974-2069.93704"},{"key":"bibr5-21501351231185118","doi-asserted-by":"publisher","DOI":"10.1093\/ejcts\/ezab078"},{"key":"bibr6-21501351231185118","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtcvs.2010.05.016"},{"key":"bibr7-21501351231185118","doi-asserted-by":"publisher","DOI":"10.1016\/j.athoracsur.2011.08.085"},{"key":"bibr8-21501351231185118","doi-asserted-by":"publisher","DOI":"10.1016\/j.athoracsur.2018.07.069"},{"key":"bibr9-21501351231185118","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtcvs.2009.10.038"},{"key":"bibr10-21501351231185118","doi-asserted-by":"publisher","DOI":"10.1016\/j.athoracsur.2010.11.058"},{"issue":"1","key":"bibr11-21501351231185118","first-page":"25","volume":"12","author":"Erez E","year":"2003","journal-title":"J Heart Valve Dis."},{"key":"bibr12-21501351231185118","doi-asserted-by":"publisher","DOI":"10.1161\/circ.104.suppl_1.I-143"},{"key":"bibr13-21501351231185118","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtcvs.2007.12.076"},{"key":"bibr14-21501351231185118","doi-asserted-by":"publisher","DOI":"10.1177\/2150135121994084"},{"key":"bibr15-21501351231185118","doi-asserted-by":"publisher","DOI":"10.1016\/j.athoracsur.2011.08.085"},{"key":"bibr16-21501351231185118","unstructured":"Food U and D. 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