{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T07:11:44Z","timestamp":1777878704912,"version":"3.51.4"},"reference-count":15,"publisher":"SAGE Publications","issue":"3","license":[{"start":{"date-parts":[[2023,12,25]],"date-time":"2023-12-25T00:00:00Z","timestamp":1703462400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["World J Pediatr Congenit Heart Surg"],"published-print":{"date-parts":[[2024,5]]},"abstract":"<jats:p>Background: The current technique used in severe mitral regurgitation in children can occasionally lead to residual regurgitation. To address this issue, the posterior annulus elevation technique was developed to enhance coaptation and reduce residual lesions. This study aims to evaluate the effectiveness of this technique in reducing residual regurgitation during mitral valve repair in children. Methods: A total of 64 patients aged &lt;18 years old undergoing mitral valve repair were randomized into two groups: the intervention (with posterior annulus elevation) group and the control group, which underwent conventional repair techniques. Various parameters, including coaptation area, residual mitral regurgitation, clinical outcomes, metabolic, and hemolytic markers, were measured on days 0, 5, 2 weeks, and 3 months after surgery. Results: The intervention group (n\u2009=\u200932) showed a significant reduction in residual mitral regurgitation compared with the control group (n\u2009=\u200932) on each evaluation. At three months after surgery, we found that the posterior annulus elevation technique could be a protective factor that reduces the chance of residual regurgitation compared with the control group (RR\u2009=\u20090.31; confidence interval: 0.18-0.54; P\u2009\u2264\u2009.001). Coaptation length and index were also found to be significantly higher in the intervention group ( P\u2009\u2264\u2009.001). Clinical outcomes, metabolic markers, and hemolysis marker did not show any significant differences between the two groups. Conclusions: The posterior annulus elevation technique demonstrated effectiveness in reducing residual mitral regurgitation and improving coaptation area in pediatric mitral valve repair. This technique showed better short-term surgical outcomes in children with mitral regurgitation compared with the conventional technique.<\/jats:p>","DOI":"10.1177\/21501351231211590","type":"journal-article","created":{"date-parts":[[2023,12,25]],"date-time":"2023-12-25T17:41:31Z","timestamp":1703526091000},"page":"353-362","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Posterior Annulus Elevation Technique in Reducing Residual Regurgitation During Mitral Valve Repair in Children: A Randomized Controlled Trial"],"prefix":"10.1177","volume":"15","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7792-9131","authenticated-orcid":false,"given":"Budi","family":"Rahmat","sequence":"first","affiliation":[{"name":"Doctoral Program in Medical Sciences, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia"},{"name":"Pediatric and Congenital Heart Surgery Unit, National Cardiovascular Center Harapan Kita, Jakarta, Indonesia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bambang Budi","family":"Siswanto","sequence":"additional","affiliation":[{"name":"Department of Cardiology and Vascular Medicine, Faculty of Medicine, Universitas Indonesia, National Cardiovascular Centre Harapan Kita, Jakarta, Indonesia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8157-7527","authenticated-orcid":false,"given":"Dicky","family":"Fakhri","sequence":"additional","affiliation":[{"name":"Pediatric and Congenital Heart Surgery Unit, National Cardiovascular Center Harapan Kita, Jakarta, Indonesia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Indriwanto","family":"Sakidjan","sequence":"additional","affiliation":[{"name":"Department of Cardiology and Vascular Medicine, Faculty of Medicine, Universitas Indonesia, National Cardiovascular Centre Harapan Kita, Jakarta, Indonesia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tri Wahyu","family":"Murni","sequence":"additional","affiliation":[{"name":"Cardiothoracic Surgery Division, Department of Surgery, Hasan Sadikin Hospital, Jawa Barat, Indonesia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ina Susianti","family":"Timan","sequence":"additional","affiliation":[{"name":"Human Genetic Research Center IMERI-FKUI, Universitas Kristen Krida Wacana, Jakarta, Indonesia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aria","family":"Kekalih","sequence":"additional","affiliation":[{"name":"Community Medicine Department, Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yovi","family":"Kurniawati","sequence":"additional","affiliation":[{"name":"Department of Cardiology and Vascular Medicine, Faculty of Medicine, Universitas Indonesia, National Cardiovascular Centre Harapan Kita, Jakarta, Indonesia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dwi Gunawan","family":"Fardhani","sequence":"additional","affiliation":[{"name":"Pediatric and Congenital Heart Surgery Unit, National Cardiovascular Center Harapan Kita, Jakarta, Indonesia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3687-399X","authenticated-orcid":false,"given":"Putu Wisnu","family":"Arya Wardana","sequence":"additional","affiliation":[{"name":"Department of Thoracic, Cardiac and Vascular Surgery, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2023,12,25]]},"reference":[{"issue":"3","key":"bibr1-21501351231211590","first-page":"230","volume":"4","author":"Mick SL","year":"2015","journal-title":"Ann Cardiothorac 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