{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T14:50:00Z","timestamp":1791903000904,"version":"4.3.4"},"reference-count":16,"publisher":"SAGE Publications","issue":"3","license":[{"start":{"date-parts":[[2024,2,25]],"date-time":"2024-02-25T00:00:00Z","timestamp":1708819200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["World J Pediatr Congenit Heart Surg"],"published-print":{"date-parts":[[2024,5]]},"abstract":"<jats:p>\n                    Background: We sought to evaluate the influence of the rudimentary ventricle on long-term outcomes after the Fontan operation, focusing on exercise capacity and cardiac performance. Methods: Between 1995 and 2021, 290 patients underwent a total cavopulmonary connection. \u201cTwo-ventricle\u201d Fontan circulation was defined as a rudimentary ventricle &gt;30% of the dominant ventricle or &gt;50% of its predicted normal value. This cohort was compared with patients with single-ventricle Fontan circulation. The primary endpoint was Fontan failure, and the secondary endpoints were VO\n                    <jats:sub>2<\/jats:sub>\n                    and cardiac catheterization data at ten years postoperatively. Results: The median follow-up after the Fontan operation was 7.9 years (interquartile range: 1.9-13.9). No significant difference was found in Fontan failure-free survival between the \u201ctwo-ventricle\u201d Fontan circulation group and the single-ventricle Fontan circulation group (83\/91, 93% vs 156\/199, 78%), respectively at 20 years; P\u2009=\u2009.11). No significant difference was found in VO\n                    <jats:sub>2<\/jats:sub>\n                    or cardiac performance except cardiac index, with 2.9 (2.3-4.8) versus 2.5 (2.3-4.3) L\/min\/m\n                    <jats:sup>2<\/jats:sup>\n                    ( P\u2009=\u2009.047). Fifty-one patients in the \u201ctwo-ventricle\u201d Fontan circulation group were followed up for over ten years after the Fontan operation. In the subgroup analysis of this cohort, the rudimentary ventricular end-diastolic volume\/dominant ventricular end-diastolic volume ratio showed a significant positive correlation with dominant ventricular end-diastolic pressure (r\u2009=\u20090.58 [95% CI 0.35-0.74], P\u2009=\u2009.002) and a significant negative correlation with VO\n                    <jats:sub>2<\/jats:sub>\n                    (r\u2009=\u2009\u22120.61 [95% CI \u22120.80 to \u22120.28], P\u2009=\u2009.001). Conclusions: The rudimentary ventricle was not significantly associated with any clinical disadvantages regarding Fontan failure. However, a large rudimentary ventricle was significantly associated with higher end-diastolic pressure and lower exercise capacity.\n                  <\/jats:p>","DOI":"10.1177\/21501351241227882","type":"journal-article","created":{"date-parts":[[2024,2,26]],"date-time":"2024-02-26T01:09:26Z","timestamp":1708909766000},"page":"270-276","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":3,"title":["Impact of the Rudimentary Chamber on Outcomes in Fontan Patients"],"prefix":"10.1177","volume":"15","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2554-4245","authenticated-orcid":false,"given":"Koji","family":"Miwa","sequence":"first","affiliation":[{"name":"Department of Cardiovascular Surgery, Osaka Women's and Children's Hospital, Izumi, Osaka, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sanae","family":"Tsumura","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Surgery, Osaka Women's and Children's Hospital, Izumi, Osaka, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tomomitsu","family":"Kanaya","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Surgery, Osaka Women's and Children's Hospital, Izumi, Osaka, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takashi","family":"Kido","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Surgery, Osaka Women's and Children's Hospital, Izumi, Osaka, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3832-4919","authenticated-orcid":false,"given":"Yuji","family":"Tominaga","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Surgery, Osaka Women's and Children's Hospital, Izumi, Osaka, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shota","family":"Kawai","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Surgery, Osaka Women's and Children's Hospital, Izumi, Osaka, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuta","family":"Teguri","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Surgery, Osaka Women's and Children's Hospital, Izumi, Osaka, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2024,2,25]]},"reference":[{"key":"bibr1-21501351241227882","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2015.07.065"},{"key":"bibr2-21501351241227882","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2017.12.054"},{"key":"bibr3-21501351241227882","doi-asserted-by":"publisher","DOI":"10.1016\/j.athoracsur.2016.04.054"},{"key":"bibr4-21501351241227882","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5223(96)70015-6"},{"key":"bibr5-21501351241227882","doi-asserted-by":"publisher","DOI":"10.1053\/j.semtcvs.2016.01.007"},{"key":"bibr6-21501351241227882","doi-asserted-by":"publisher","DOI":"10.1177\/0218492317717412"},{"key":"bibr7-21501351241227882","doi-asserted-by":"publisher","DOI":"10.1016\/j.athoracsur.2018.08.024"},{"key":"bibr8-21501351241227882","doi-asserted-by":"publisher","DOI":"10.1093\/ejcts\/ezab194"},{"key":"bibr9-21501351241227882","doi-asserted-by":"publisher","DOI":"10.1016\/S0735-1097(01)01266-9"},{"key":"bibr10-21501351241227882","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2017.03.582"},{"key":"bibr11-21501351241227882","doi-asserted-by":"publisher","DOI":"10.1067\/mtc.2001.116947"},{"key":"bibr12-21501351241227882","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.113.007764"},{"key":"bibr13-21501351241227882","doi-asserted-by":"publisher","DOI":"10.1016\/s1010-7940(03)00186-6"},{"key":"bibr14-21501351241227882","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtcvs.2021.04.076"},{"key":"bibr15-21501351241227882","doi-asserted-by":"publisher","DOI":"10.1053\/j.pcsu.2022.04.003"},{"key":"bibr16-21501351241227882","doi-asserted-by":"publisher","DOI":"10.1136\/hrt.66.5.375"}],"container-title":["World 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