{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T07:12:12Z","timestamp":1777878732609,"version":"3.51.4"},"reference-count":25,"publisher":"SAGE Publications","issue":"6","license":[{"start":{"date-parts":[[2024,8,28]],"date-time":"2024-08-28T00:00:00Z","timestamp":1724803200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["World J Pediatr Congenit Heart Surg"],"published-print":{"date-parts":[[2024,11]]},"abstract":"<jats:p>Background: Aortic valve disease results in left ventricular (LV) dilation and\/or hypertrophy. Valve intervention may improve, but not normalize flow dynamics. We hypothesized that LV remodeling would be more favorable following the Ross procedure versus mechanical aortic valve replacement (mAVR). Methods: Patients who were 18 to 50 years of age and underwent Ross or mAVR from 2000 to 2016 at a single institution were retrospectively reviewed. Propensity score matching was performed and yielded 27 well-matched pairs. Demographics and echocardiographic variables of LV morphology and wall thickness were collected. Those with\u2009&gt;\u2009mild residual valve disease were excluded. Primary endpoints included LV morphology. T test and Fisher exact test analysis were used for statistical comparison. Results: Average age at operation (Ross 35.3\u2009\u00b1\u200910.2 vs mAVR 37.3\u2009\u00b1\u20098.9 years) did not differ. Indication for operation was similar between groups. Preoperative echocardiographic variables did not differ. At average follow-up duration (Ross 7.9\u2009\u00b1\u20092.4 vs mAVR 7.3\u2009\u00b1\u20092.4 years), wall thickness was significantly smaller for Ross compared with mAVR ( P\u2009=\u2009.00715). Only 4\/27 (15%) of mAVR patients had normalized LV parameters compared with 16\/27 (59%) of Ross patients ( P\u2009=\u2009.000813). Residual hypertrophy was the most common long-term abnormality for mAVR. Conclusion: Following aortic valve replacement with the Ross procedure or mechanical aortic valve prosthesis, the Ross conferred more favorable LV remodeling compared with mAVR. Future directions include analyzing longer follow-up to determine if patterns persist and the impact on cardiac morbidity and mortality.<\/jats:p>","DOI":"10.1177\/21501351241266122","type":"journal-article","created":{"date-parts":[[2024,8,28]],"date-time":"2024-08-28T12:01:27Z","timestamp":1724846487000},"page":"801-805","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":3,"title":["Ross Confers More Favorable Left Ventricular Remodeling Compared With Mechanical Aortic Valve Replacement"],"prefix":"10.1177","volume":"15","author":[{"ORCID":"https:\/\/orcid.org\/0009-0000-1304-4115","authenticated-orcid":false,"given":"Garrett H.","family":"Markham","sequence":"first","affiliation":[{"name":"Department of Biomedical Engineering, University of Arkansas, Fayetteville, AR, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"John W.","family":"Brown","sequence":"additional","affiliation":[{"name":"Division of Congenital Cardiac Surgery, Department of Surgery, Riley Hospital for Children at IU Health, Indiana University School of Medicine, Indianapolis, IN, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chelsea D.","family":"Wenos","sequence":"additional","affiliation":[{"name":"Department of Surgery, University of Nebraska Medical Center, Omaha, NE, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Morten O.","family":"Jensen","sequence":"additional","affiliation":[{"name":"Department of Biomedical Engineering, Department of Surgery, University of Arkansas for Medical Sciences, University of Arkansas, Little Rock, AR, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hanna K.","family":"Jensen","sequence":"additional","affiliation":[{"name":"Department of Surgery, University of Arkansas for Medical Sciences, Little Rock, AR, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Larry W.","family":"Markham","sequence":"additional","affiliation":[{"name":"Division of Cardiology, Department of Pediatrics, Riley Hospital for Children at IU Health, Indiana University School of Medicine, Indianapolis, IN, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7818-0548","authenticated-orcid":false,"given":"Jeremy L.","family":"Herrmann","sequence":"additional","affiliation":[{"name":"Division of Congenital Cardiac Surgery, Department of Surgery, Riley Hospital for Children at IU Health, Indiana University School of Medicine, Indianapolis, IN, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2024,8,28]]},"reference":[{"key":"bibr1-21501351241266122","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(67)90794-5"},{"key":"bibr2-21501351241266122","doi-asserted-by":"publisher","DOI":"10.1111\/jocs.16831"},{"issue":"3","key":"bibr3-21501351241266122","first-page":"162","volume":"13","author":"Patten RD","year":"1998","journal-title":"Curr Opin Cardiol"},{"key":"bibr4-21501351241266122","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199005313222203"},{"key":"bibr5-21501351241266122","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2003.12.053"},{"key":"bibr6-21501351241266122","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2015.10.076"},{"issue":"2","key":"bibr7-21501351241266122","first-page":"253","volume":"15","author":"Brown JW","year":"2006","journal-title":"J Heart Valve Dis"},{"key":"bibr8-21501351241266122","doi-asserted-by":"publisher","DOI":"10.1016\/j.athoracsur.2009.05.014"},{"issue":"3","key":"bibr9-21501351241266122","first-page":"332","volume":"20","author":"Brown JW","year":"2011","journal-title":"J Heart Valve Dis"},{"issue":"1","key":"bibr10-21501351241266122","first-page":"43","volume":"10","author":"Legarra JJ","year":"2001","journal-title":"J Heart Valve Dis"},{"key":"bibr11-21501351241266122","doi-asserted-by":"publisher","DOI":"10.1111\/j.1540-8191.2005.00133.x"},{"key":"bibr12-21501351241266122","doi-asserted-by":"publisher","DOI":"10.1016\/j.hlc.2013.07.008"},{"key":"bibr13-21501351241266122","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9149(98)01062-5"},{"key":"bibr14-21501351241266122","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5223(00)70211-X"},{"key":"bibr15-21501351241266122","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5223(00)70175-9"},{"key":"bibr16-21501351241266122","doi-asserted-by":"publisher","DOI":"10.1067\/mtc.2001.113752"},{"key":"bibr17-21501351241266122","doi-asserted-by":"publisher","DOI":"10.1016\/j.athoracsur.2011.02.012"},{"issue":"6","key":"bibr18-21501351241266122","first-page":"767","volume":"22","author":"Stelzer P","year":"2013","journal-title":"J Heart Valve Dis"},{"key":"bibr19-21501351241266122","doi-asserted-by":"publisher","DOI":"10.1177\/2150135114537532"},{"issue":"3","key":"bibr20-21501351241266122","doi-asserted-by":"crossref","DOI":"10.1161\/CIRCULATIONAHA.120.050363","volume":"129","author":"Nishimura RA","year":"2014","journal-title":"Circulation"},{"key":"bibr21-21501351241266122","first-page":"40","volume":"14","author":"Concha M","year":"2004","journal-title":"J Heart Valve Dis"},{"key":"bibr22-21501351241266122","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtcvs.2013.10.064"},{"key":"bibr23-21501351241266122","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.116.022800"},{"key":"bibr24-21501351241266122","doi-asserted-by":"publisher","DOI":"10.1093\/icvts\/ivw325"},{"key":"bibr25-21501351241266122","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijcard.2013.11.034"}],"container-title":["World Journal for Pediatric and Congenital Heart Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/21501351241266122","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/21501351241266122","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/21501351241266122","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T23:26:38Z","timestamp":1777591598000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/21501351241266122"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,8,28]]},"references-count":25,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2024,11]]}},"alternative-id":["10.1177\/21501351241266122"],"URL":"https:\/\/doi.org\/10.1177\/21501351241266122","relation":{},"ISSN":["2150-1351","2150-136X"],"issn-type":[{"value":"2150-1351","type":"print"},{"value":"2150-136X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,8,28]]}}}