{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,8]],"date-time":"2026-06-08T14:11:56Z","timestamp":1780927916228,"version":"3.54.1"},"reference-count":21,"publisher":"SAGE Publications","issue":"4","license":[{"start":{"date-parts":[[2025,12,3]],"date-time":"2025-12-03T00:00:00Z","timestamp":1764720000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["World J Pediatr Congenit Heart Surg"],"published-print":{"date-parts":[[2026,7]]},"abstract":"<jats:p>\n                    <jats:bold>Background:<\/jats:bold>\n                    ABO-Incompatible (ABO-I) heart transplantation (HT) is a promising strategy to extend the hope of HT to many infants and children facing donor organ shortages and waitlist mortality. Despite increasing experience with ABO-I HT and comparable outcomes, universal adoption of this strategy has yet to be achieved. We aimed to provide a contemporary analysis of ABO-I HT with emphasis on the impact of the 2016 United Network for Organ Sharing policy change.\n                    <jats:bold>Methods:<\/jats:bold>\n                    This is a retrospective study of the Organ Procurement and Transplantation Network database examining patients listed for HT at \u22642 years of age in two eras: July 7, 2008, to July 7, 2016, and July 8, 2016, to July 8, 2024, to account for allocation policy changes. The primary outcome was posttransplant survival. Additional outcomes included waitlist mortality, center volume-survival relationship, and incidence of postoperative complications.\n                    <jats:bold>Results:<\/jats:bold>\n                    A total of 2,770 children underwent HT; 493 (18%) were ABO-I recipients. Frequency of ABO-I HT increased across the study period; there was no difference in waitlist mortality for ABO-I eligible candidates across eras (hazard ratio [HR] 0.70, confidence interval [CI 0.48-1.02,\n                    <jats:italic toggle=\"yes\">P<\/jats:italic>\n                    \u2009=\u2009.07). No differences were observed in one- or five-year survival between ABO-I and ABO-compatible (ABO-C) cohorts. There was no difference in survival among ABO-I recipients between high-volume centers (HVCs) and non-HVCs (HR 0.87, CI 0.43-1.76,\n                    <jats:italic toggle=\"yes\">P<\/jats:italic>\n                    \u2009=\u2009.70).\n                    <jats:bold>Conclusions:<\/jats:bold>\n                    ABO-Incompatible transplantation offers comparable posttransplant outcomes with ABO-C transplantation, regardless of center volume. The 2016 United Network for Organ Sharing policy has not impacted waitlist mortality for this population. These data provide support for universal adoption of ABO-I HT in appropriately selected patients as the standard of care for infants and children awaiting HT.\n                  <\/jats:p>","DOI":"10.1177\/21501351251386421","type":"journal-article","created":{"date-parts":[[2025,12,3]],"date-time":"2025-12-03T13:16:13Z","timestamp":1764767773000},"page":"468-476","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["ABO-Incompatible Heart Transplantation Remains Underutilized Despite Comparable Outcomes in Pediatric Heart Transplantation"],"prefix":"10.1177","volume":"17","author":[{"ORCID":"https:\/\/orcid.org\/0009-0002-2808-9281","authenticated-orcid":false,"given":"Tiffany E.","family":"Maksimuk","sequence":"first","affiliation":[{"name":"University of Colorado School of Medicine, Anschutz Medical Campus"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicole M.","family":"Mott","sequence":"additional","affiliation":[{"name":"University of Colorado Anschutz Medical Center"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kaitlyn","family":"Dickinson","sequence":"additional","affiliation":[{"name":"University of Colorado Anschutz Medical Center"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lawrence B.","family":"Brown","sequence":"additional","affiliation":[{"name":"The Johns Hopkins Hospital"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Otto","family":"Thielen","sequence":"additional","affiliation":[{"name":"University of Colorado Anschutz Medical Center"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Syed Shahyan","family":"Bakhtiyar","sequence":"additional","affiliation":[{"name":"University of Colorado Anschutz Medical Center"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael T.","family":"Cain","sequence":"additional","affiliation":[{"name":"University of Colorado, Anschutz Medical Center"},{"name":"University of Colorado Hospital Transplant Center, Aurora, CO, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jordan R. H.","family":"Hoffman","sequence":"additional","affiliation":[{"name":"University of Colorado, Anschutz Medical Center"},{"name":"University of Colorado Hospital Transplant Center, Aurora, CO, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Melanie D.","family":"Everitt","sequence":"additional","affiliation":[{"name":"Children's Hospital of Colorado"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matthew","family":"Stone","sequence":"additional","affiliation":[{"name":"University of Colorado, Anschutz Medical Center"},{"name":"Division of Cardiothoracic Surgery, Department of Surgery, Children's Hospital of Colorado, Aurora, CO, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2025,12,3]]},"reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.surg.2023.02.015"},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.healun.2024.03.019"},{"key":"e_1_3_3_4_2","doi-asserted-by":"publisher","DOI":"10.1056\/nejm200103153441102"},{"key":"e_1_3_3_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.healun.2012.11.022"},{"key":"e_1_3_3_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.healun.2011.11.013"},{"key":"e_1_3_3_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.healun.2020.02.008"},{"key":"e_1_3_3_8_2","unstructured":"OPTN Organ Procurement & Transplantation Network. 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