{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,31]],"date-time":"2026-05-31T12:03:48Z","timestamp":1780229028006,"version":"3.54.0"},"reference-count":20,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2026,5,28]],"date-time":"2026-05-28T00:00:00Z","timestamp":1779926400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["World J Pediatr Congenit Heart Surg"],"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>This study analyzed the utility of the pulmonary artery flow study (PAFS) in prognostic assessment for children with pulmonary atresia and ventricular septal defect (PA\/VSD).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We reviewed 121 patients with type B or C pulmonary atresia and ventricular septal defect (PA\/VSD) who underwent the PAFS between August 2016 and August 2024. Demographic, operative, and follow-up data were collected. Statistical analyses included Spearman's correlation, ROC curves, and Kaplan-Meier survival analysis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      The cohort included 60 males and 61 females, with 97 type B and 24 type C cases. Mean age was 44 months and median weight was 12.8\u2005kg. Mean pulmonary artery pressure (mPAP) strongly correlated with postoperative right ventricular systolic pressure\/left ventricular systolic pressure (RVSP\/LVSP) (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      \u2009=\u20090.000). An mPAP cutoff of 24.5 mmHg predicted VSD closure with 79.2% sensitivity and 91.2% specificity. Mean pulmonary artery pressure and RVSP\/LVSP were associated with prolonged ventilation and critical care unit stay. During follow-up, 15\/121 children (12.4%) died, with significantly poorer survival in those with mPAP\u2009&gt;\u200925\u2005mmHg (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      \u2009=\u20090.009).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>The pulmonary artery flow study is a valuable predictor of successful VSD closure and postoperative outcomes. An mPAP threshold of 25\u2005mmHg may help identify high-risk patients requiring more intensive management.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/21501351261434210","type":"journal-article","created":{"date-parts":[[2026,5,28]],"date-time":"2026-05-28T14:14:57Z","timestamp":1779977697000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["A Single-Center Clinical Analysis of 121 Pediatric Cases with Pulmonary Atresia and Ventricular Septal Defect Undergoing the Pulmonary Artery Flow Study"],"prefix":"10.1177","author":[{"ORCID":"https:\/\/orcid.org\/0009-0000-2157-2428","authenticated-orcid":false,"given":"Fan","family":"Cao","sequence":"first","affiliation":[{"name":"Department of Cardiovascular Surgery, Women and Children's Medical Center Affiliated to Guangzhou Medical University, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangzhou, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wenhua","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Disease, General Hospital of the Southern Theater Command, Guangzhou, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rongjun","family":"Zou","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Surgery, Guangdong Provincial Hospital of Chinese Medicine, The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lijuan","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Surgery, Women and Children's Medical Center Affiliated to Guangzhou Medical University, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangzhou, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Na","family":"Zhou","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Surgery, Women and Children's Medical Center Affiliated to Guangzhou Medical University, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangzhou, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chengbin","family":"Zhou","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Surgery, Guangdong Cardiovascular Institute, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Southern Medical University, Guangzhou, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Li","family":"Ma","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Surgery, Women and Children's Medical Center Affiliated to Guangzhou Medical University, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangzhou, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2026,5,28]]},"reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.athoracsur.2019.01.046"},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10396-017-0809-2"},{"key":"e_1_3_3_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9149(78)90941-4"},{"key":"e_1_3_3_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/s0022-5223(95)70305-5"},{"key":"e_1_3_3_6_2","doi-asserted-by":"publisher","DOI":"10.1136\/hrt.2005.083295"},{"key":"e_1_3_3_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtcvs.2009.08.011"},{"key":"e_1_3_3_8_2","doi-asserted-by":"publisher","DOI":"10.1053\/j.pcsu.2009.01.018"},{"key":"e_1_3_3_9_2","doi-asserted-by":"publisher","DOI":"10.3389\/fcvm.2022.836200"},{"key":"e_1_3_3_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/s0022-5223(97)70258-7"},{"key":"e_1_3_3_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.athoracsur.2017.05.020"},{"key":"e_1_3_3_12_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.108.844084"},{"key":"e_1_3_3_13_2","doi-asserted-by":"publisher","DOI":"10.1051\/ject\/201951147"},{"key":"e_1_3_3_14_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.heliyon.2024.e27109"},{"key":"e_1_3_3_15_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.athoracsur.2015.03.110"},{"key":"e_1_3_3_16_2","doi-asserted-by":"publisher","DOI":"10.1161\/circinterventions.116.004952"},{"key":"e_1_3_3_17_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtcvs.2016.07.082"},{"key":"e_1_3_3_18_2","doi-asserted-by":"publisher","DOI":"10.1093\/ejcts\/ezr310"},{"key":"e_1_3_3_19_2","doi-asserted-by":"publisher","DOI":"10.1053\/j.pcsu.2009.01.017"},{"key":"e_1_3_3_20_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00246-011-9958-z"},{"key":"e_1_3_3_21_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.athoracsur.2011.08.082"}],"container-title":["World Journal for Pediatric and Congenital Heart Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/21501351261434210","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/21501351261434210","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/21501351261434210","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,31]],"date-time":"2026-05-31T11:46:38Z","timestamp":1780227998000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/21501351261434210"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,5,28]]},"references-count":20,"alternative-id":["10.1177\/21501351261434210"],"URL":"https:\/\/doi.org\/10.1177\/21501351261434210","relation":{},"ISSN":["2150-1351","2150-136X"],"issn-type":[{"value":"2150-1351","type":"print"},{"value":"2150-136X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,5,28]]},"article-number":"21501351261434210"}}