{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,10]],"date-time":"2026-09-10T18:09:35Z","timestamp":1789063775462,"version":"build-2803163510"},"reference-count":12,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2026,9,8]],"date-time":"2026-09-08T00:00:00Z","timestamp":1788825600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["World J Pediatr Congenit Heart Surg"],"abstract":"<jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>While many studies view patients with hypoplastic left heart syndrome (HLHS) through the lens of financial burden, an overall sense of the medical burden of these patients has rarely been reported. We sought to introduce a granular analysis of the medical burden of patients with HLHS to capture a view of their journey to adulthood.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Children with HLHS (\u226418 years) born from 2004 to 2008 with 18 years of follow-up were identified in the Pediatric Health Information System (PHIS). Children who did not have 18 years of complete follow-up were excluded.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>By 1 year of age, a child with HLHS had a total median number of visits of 4 (3-6), length of stay (LOS) of 52 days (d) (29-87), 2 (1-3) cardiac catheterizations, 55 (42-74) unique drugs, and 4% cardiac transplant prevalence. By 5 years of age, a child with HLHS had a total number of visits of 10 (6-18), LOS of 73d (46-119), 3 (2-6) cardiac catheterizations, 89 (70-132) unique drugs, and a 10% cardiac transplant prevalence. By 10 years of age, a child with HLHS had a total number of visits of 18 (8-35), LOS of 85d (54-147), 5 (3-8) cardiac catheterizations, 120 (97-178) unique drugs, and an11% cardiac transplant prevalence. By 18 years of age, an adult with HLHS had a total number of visits of 44 (17-80), LOS of 154d (83-264), 9 (5-12) cardiac catheterizations, 139 (127-220) unique drugs, and a 19% cardiac transplant prevalence.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>The present report offers detailed insight into the medical burden of patients with HLHS and can serve as a reference to inform patients and families of the journey.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/21501351261472468","type":"journal-article","created":{"date-parts":[[2026,9,8]],"date-time":"2026-09-08T17:31:35Z","timestamp":1788888695000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Unveiling the Healthcare Journey of Patients with Hypoplastic Left Heart Syndrome: From Birth to Adulthood"],"prefix":"10.1177","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9980-0160","authenticated-orcid":false,"given":"Amir","family":"Mehdizadeh-Shrifi","sequence":"first","affiliation":[{"name":"The Heart Institute"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0005-3834-1542","authenticated-orcid":false,"given":"Muhammad","family":"Faateh","sequence":"additional","affiliation":[{"name":"The Heart Institute"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4641-989X","authenticated-orcid":false,"given":"Darren","family":"Turner","sequence":"additional","affiliation":[{"name":"The Heart Institute"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kevin","family":"Kulshrestha","sequence":"additional","affiliation":[{"name":"The Heart Institute"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Haleh C.","family":"Heydarian","sequence":"additional","affiliation":[{"name":"Cincinnati Children's Hospital Medical Center"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Md Monir","family":"Hossain","sequence":"additional","affiliation":[{"name":"Cincinnati Children's Hospital Medical Center"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0766-3715","authenticated-orcid":false,"given":"Spencer","family":"Hogue","sequence":"additional","affiliation":[{"name":"The Heart Institute"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nadine","family":"Kasparian","sequence":"additional","affiliation":[{"name":"The Heart Institute"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4112-9823","authenticated-orcid":false,"given":"Awais","family":"Ashfaq","sequence":"additional","affiliation":[{"name":"The Heart Institute"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Russel","family":"Hirsch","sequence":"additional","affiliation":[{"name":"Cincinnati Children's Hospital Medical Center"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David L.S.","family":"Morales","sequence":"additional","affiliation":[{"name":"The Heart Institute"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2026,9,8]]},"reference":[{"key":"e_1_3_4_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2011.09.022"},{"key":"e_1_3_4_3_2","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2014-1427"},{"key":"e_1_3_4_4_2","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2010-3742"},{"key":"e_1_3_4_5_2","doi-asserted-by":"publisher","DOI":"10.1177\/21501351221122971"},{"key":"e_1_3_4_6_2","unstructured":"Weiss AJ Liang L Martin K. Overview of hospital stays among children and adolescents 2019. In: Healthcare Cost and Utilization Project (HCUP) Statistical Briefs. Internet. Rockville MD: Agency for Healthcare Research and Quality (US); 2006-Feb-Statistical Brief #299 2022. PMID: 36622925."},{"key":"e_1_3_4_7_2","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2011-2879"},{"key":"e_1_3_4_8_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00228-012-1354-y"},{"key":"e_1_3_4_9_2","doi-asserted-by":"publisher","DOI":"10.9740\/mhc.2021.11.320"},{"key":"e_1_3_4_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.rcl.2011.06.003"},{"key":"e_1_3_4_11_2","doi-asserted-by":"publisher","DOI":"10.1001\/archpediatrics.2010.270"},{"key":"e_1_3_4_12_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.athoracsur.2021.04.008"},{"key":"e_1_3_4_13_2","doi-asserted-by":"publisher","DOI":"10.1111\/chd.12732"}],"container-title":["World Journal for Pediatric and Congenital Heart Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/21501351261472468","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/21501351261472468","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/21501351261472468","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,10]],"date-time":"2026-09-10T17:52:02Z","timestamp":1789062722000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/21501351261472468"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,9,8]]},"references-count":12,"alternative-id":["10.1177\/21501351261472468"],"URL":"https:\/\/doi.org\/10.1177\/21501351261472468","relation":{},"ISSN":["2150-1351","2150-136X"],"issn-type":[{"value":"2150-1351","type":"print"},{"value":"2150-136X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,9,8]]},"article-number":"21501351261472468"}}