{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T21:24:19Z","timestamp":1792013059031,"version":"4.4.0"},"reference-count":29,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T00:00:00Z","timestamp":1777593600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T00:00:00Z","timestamp":1777593600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Geriatr Orthop Surg Rehabil"],"published-print":{"date-parts":[[2026,5]]},"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>The demand for total knee arthroplasty, an established treatment for advanced knee osteoarthritis, is anticipated to increase among individuals aged \u226580 years. Given the high prevalence of multimorbidity among older adults in Japan, in this study, we aimed to elucidate the relationship between multimorbidity and post-operative walking independence in this demographic.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      This retrospective cohort study included patients who underwent total knee arthroplasty for knee osteoarthritis between October 2023 and September 2024; those who underwent other surgeries or had significant mobility limitations were excluded. Patients aged \u226580 years with a Charlson Comorbidity Index of \u22652 were categorized into the \u201colder patients with multimorbidity\u201d group. The primary outcome was walking independence, which was assessed using the Functional Ambulation Category. Demographic and clinical variables were evaluated as potential confounders. Statistical tests included Student\u2019s\n                      <jats:italic toggle=\"yes\">t<\/jats:italic>\n                      -test, Mann\u2013Whitney\n                      <jats:italic toggle=\"yes\">U<\/jats:italic>\n                      test, chi-square test, and hierarchical multiple regression analysis; a\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      -value of &lt;0.05 was considered significant.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Thirteen and 42 patients were classified as \u201colder patients with multimorbidity\u201d and controls, respectively. Significant intergroup differences were observed in age, height, weight, and hemoglobin levels but not in the length of hospital stay and overall outcomes. Functional Ambulation Category scores declined postoperatively in both groups, with no significant intergroup difference in independent walking ability. Hierarchical multiple regression analysis of pooled data revealed no significant association between age or multimorbidity and walking independence at discharge.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>The findings indicate that age and multimorbidity are not primary determinants of post-operative walking independence. Individualized rehabilitation may improve recovery outcomes, underscoring the potential benefits of standardizing postoperative care for older patients with multimorbidity who have undergone total knee arthroplasty.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/21514593261446118","type":"journal-article","created":{"date-parts":[[2026,5,5]],"date-time":"2026-05-05T20:56:52Z","timestamp":1778014612000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":1,"title":["Association Between Multimorbidity and Walking Independence After Total Knee Arthroplasty in Adults Aged \u226580 Years: A Retrospective Cohort Study"],"prefix":"10.1177","volume":"17","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9323-8146","authenticated-orcid":false,"given":"Makoto","family":"Asaeda","sequence":"first","affiliation":[{"name":"Hiroshima University Hospital"},{"name":"Hiroshima University Hospital"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yukio","family":"Mikami","sequence":"additional","affiliation":[{"name":"Hiroshima University Hospital"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Atsuo","family":"Nakamae","sequence":"additional","affiliation":[{"name":"Graduate School of Biomedical and Health Sciences"},{"name":"Hiroshima University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tomoyuki","family":"Nakasa","sequence":"additional","affiliation":[{"name":"Graduate School of Biomedical and Health Sciences"},{"name":"Hiroshima University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Akinori","family":"Nekomoto","sequence":"additional","affiliation":[{"name":"Graduate School of Biomedical and Health Sciences"},{"name":"Hiroshima University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Noriaki","family":"Maeda","sequence":"additional","affiliation":[{"name":"School of Sport and Sciences"},{"name":"Waseda University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kiyo","family":"Ueda","sequence":"additional","affiliation":[{"name":"Hiroshima University Hospital"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takeya","family":"Araki","sequence":"additional","affiliation":[{"name":"Hiroshima University Hospital"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nobuo","family":"Adachi","sequence":"additional","affiliation":[{"name":"Graduate School of Biomedical and Health Sciences"},{"name":"Hiroshima University"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2026,5,5]]},"reference":[{"key":"e_1_3_6_2_2","doi-asserted-by":"publisher","DOI":"10.1080\/14397595.2016.1226471"},{"key":"e_1_3_6_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.joca.2010.06.001"},{"key":"e_1_3_6_4_2","unstructured":"Ministry of Health Labour and Welfare. 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