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The primary objective of this study was to evaluate the feasibility and acceptability of an integrated virtual reality (VR)-based mirror exposure therapy and eye-tracking-driven attentional bias (AB) modification training protocol\u2014previously tested in a female-based randomized controlled trial\u2014in two male adolescents with AN. Both participants received concurrent multidisciplinary care, with one case featuring comorbid muscle dysmorphia. Feasibility was assessed via protocol adherence and technical stability. Acceptability was measured using the System Usability Scale (SUS). Secondary exploratory measures included eye-tracking AB and clinical questionnaire outcomes (body dissatisfaction, drive for thinness, body anxiety, body appreciation) at pretreatment, posttreatment, and 3-month follow-up. Feasibility indicators were consistently positive: Both participants completed all sessions, reported high perceived usability (SUS &gt; 80), and no technical incidents occurred. Exploratory clinical observations suggested improvements in body dissatisfaction, weight-related anxiety, and body appreciation, with effects maintained at the 3-month follow-up. Eye-tracking data revealed divergent attentional profiles: the patient with a typical AN presentation showed heightened attention to weight-related body areas, whereas the patient with muscle dysmorphia displayed a more complex pattern oriented toward muscular regions. Given the concurrent multidisciplinary treatment, clinical improvements cannot be attributed solely to the VR intervention; however, these cases show that the protocol is a viable and well-tolerated tool that warrants further investigation in a randomized controlled trial with AN male adolescents.<\/jats:p>","DOI":"10.1177\/21522715261451681","type":"journal-article","created":{"date-parts":[[2026,5,25]],"date-time":"2026-05-25T06:09:52Z","timestamp":1779689392000},"page":"497-505","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Virtual Reality Mirror Exposure Combined with Eye-Tracking Attentional Bias Modification in Adolescent Males with Anorexia Nervosa: A Feasibility Study"],"prefix":"10.1177","volume":"29","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2918-4558","authenticated-orcid":false,"given":"Franck-Alexandre","family":"Meschberger-Annweiler","sequence":"first","affiliation":[{"name":"Department of Clinical Psychology and Psychobiology, Facultat de Psicologia, Universitat de Barcelona, Barcelona, Spain."},{"name":"Institut de Neurociences (UBneuro), Universitat de Barcelona, Barcelona, Spain."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marta","family":"Carulla-Roig","sequence":"additional","affiliation":[{"name":"Department of Child and Adolescent Psychiatry and Psychology, Hospital Sant Joan de D\u00e9u of Barcelona, Barcelona, Spain."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mariarca","family":"Ascione","sequence":"additional","affiliation":[{"name":"Department of Clinical Psychology and Psychobiology, Facultat de Psicologia, Universitat de Barcelona, Barcelona, Spain."},{"name":"Institut de Neurociences (UBneuro), Universitat de Barcelona, Barcelona, Spain."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bruno","family":"Porras-Garcia","sequence":"additional","affiliation":[{"name":"Brain, Cognition and Behavior Research Group, Consorci Sanitari de Terrassa, Terrassa, Spain."},{"name":"Department of Psychology, BrainXR Lab, Universitat Internacional de Catalunya, Sant Cugat del Valles, Spain."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eduardo","family":"Serrano-Troncoso","sequence":"additional","affiliation":[{"name":"Department of Child and Adolescent Psychiatry and Psychology, Hospital Sant Joan de D\u00e9u of Barcelona, Barcelona, Spain."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marta","family":"Ferrer-Garcia","sequence":"additional","affiliation":[{"name":"Department of Clinical Psychology and Psychobiology, Facultat de Psicologia, Universitat de Barcelona, Barcelona, Spain."},{"name":"Institut de Neurociences (UBneuro), Universitat de Barcelona, Barcelona, Spain."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jose","family":"Gutierrez-Maldonado","sequence":"additional","affiliation":[{"name":"Department of Clinical Psychology and Psychobiology, Facultat de Psicologia, Universitat de Barcelona, Barcelona, Spain."},{"name":"Institut de Neurociences (UBneuro), Universitat de Barcelona, Barcelona, Spain."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2026,5,24]]},"reference":[{"key":"e_1_3_2_2_1","doi-asserted-by":"publisher","DOI":"10.1176\/appi.books.9780890425787"},{"key":"e_1_3_2_3_1","doi-asserted-by":"publisher","DOI":"10.1097\/YCO.0000000000000739"},{"key":"e_1_3_2_4_1","first-page":"470","volume-title":"The Oxford Handbook of Eating Disorders","author":"Guti\u00e9rrez-Maldonado J","year":"2018","unstructured":"3.Guti\u00e9rrez-Maldonado J, , Ferrer-Garc\u00eda M, , Dakanalis A, et al. 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