{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T20:35:50Z","timestamp":1792787750269,"version":"4.5.0"},"reference-count":4,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T00:00:00Z","timestamp":1791936000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"name":"National Natural Science Foundation of China","award":["81870373"],"award-info":[{"award-number":["81870373"]}],"id":[{"id":"https:\/\/ror.org\/01h0zpd94","id-type":"ROR","asserted-by":"crossref"}]},{"name":"Clinical Research in Health Industry of Shanghai Municipal Health Commission","award":["202040479"],"award-info":[{"award-number":["202040479"]}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Cellular Reprogramming"],"abstract":"<jats:p>\n                    Infantile liver failure syndrome 2 (ILFS2, OMIM 616483) is a rare autosomal recessive disorder caused by neuroblastoma amplified sequence (\n                    <jats:italic toggle=\"yes\">NBAS<\/jats:italic>\n                    ) gene mutation, resulting in recurrent episodes of acute liver failure (ALF). The first onset of ALF is more common in infancy or early childhood. Recently, we identified a compound heterozygous mutation, c.3596G&gt;A (p.C1199Y)\/ex.9del (p.216-248del), in the\n                    <jats:italic toggle=\"yes\">NBAS<\/jats:italic>\n                    gene in a patient with ILFS2. The human dermal fibroblasts (HDFs) of the patient were obtained, and a line of induced pluripotent stem cells (iPSCs) was successfully generated. The iPSC line will be useful for further study of the pathogenesis and physiology of ILFS2.\n                  <\/jats:p>","DOI":"10.1177\/21524971261497947","type":"journal-article","created":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T09:18:44Z","timestamp":1791969524000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Generation of an Induced Pluripotent Stem Cell Line from a Patient with Infantile Liver Failure Syndrome 2 Carrying a Compound Heterozygous Mutation in\n                    <i>NBAS<\/i>"],"prefix":"10.1177","author":[{"given":"Bingxin","family":"Jiang","sequence":"first","affiliation":[{"name":"Department of Gastroenterology, Hepatology and Nutrition, Shanghai Children\u2019s Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yixuan","family":"Song","sequence":"additional","affiliation":[{"name":"Department of Histoembryology, Genetics and Developmental Biology, Shanghai Key Laboratory of Reproductive Medicine, Shanghai Jiao Tong University School of Medicine, Shanghai, China."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lianhu","family":"Yu","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, Hepatology and Nutrition, Shanghai Children\u2019s Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yizhong","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, Hepatology and Nutrition, Shanghai Children\u2019s Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China."},{"name":"Institute of Pediatric Infection, Immunity and Critical Care Medicine, Shanghai Children\u2019s Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2033-7826","authenticated-orcid":false,"given":"Ting","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, Hepatology and Nutrition, Shanghai Children\u2019s Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China."},{"name":"Institute of Pediatric Infection, Immunity and Critical Care Medicine, Shanghai Children\u2019s Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2026,10,14]]},"reference":[{"key":"e_1_3_5_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajhg.2015.05.009"},{"key":"e_1_3_5_3_1","doi-asserted-by":"publisher","DOI":"10.3389\/fped.2020.607005"},{"key":"e_1_3_5_4_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10545-015-9896-7"},{"key":"e_1_3_5_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2006.07.024"}],"container-title":["Cellular Reprogramming"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/21524971261497947","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/21524971261497947","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/21524971261497947","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T07:46:47Z","timestamp":1792136807000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/21524971261497947"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,10,14]]},"references-count":4,"alternative-id":["10.1177\/21524971261497947"],"URL":"https:\/\/doi.org\/10.1177\/21524971261497947","relation":{},"ISSN":["2152-4971","2152-4998"],"issn-type":[{"value":"2152-4971","type":"print"},{"value":"2152-4998","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,10,14]]},"article-number":"21524971261497947"}}