{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T13:18:28Z","timestamp":1777468708402,"version":"3.51.4"},"reference-count":66,"publisher":"SAGE Publications","issue":"9-10","license":[{"start":{"date-parts":[[2025,12,1]],"date-time":"2025-12-01T00:00:00Z","timestamp":1764547200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Brain Connectivity"],"published-print":{"date-parts":[[2025,12]]},"abstract":"<jats:sec>\n                    <jats:title>Design:<\/jats:title>\n                    <jats:p>As the cerebellum has reciprocal communications with the frontal cortex, this retrospective cohort study examined the effects of dual-site repetitive transcranial magnetic stimulation (ds-rTMS: dorsolateral prefrontal cortex [DLPFC] + cerebellum) in disorders of consciousness (DoC).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Setting:<\/jats:title>\n                    <jats:p>Single-center study in the Department of Rehabilitation of Jinhua Hospital of TCM Affiliated to Zhejiang University of Traditional Chinese Medicine.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Participants:<\/jats:title>\n                    <jats:p>Twenty-nine patients with DoC.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Intervention:<\/jats:title>\n                    <jats:p>Systematic review of clinical records comparing ds-TMS (DLPFC + cerebellum) with conventional single-site DLPFC-rTMS.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Main Measures:<\/jats:title>\n                    <jats:p>Coma Recovery Scale-Revised (CRS-R) scores, mismatch negativity (MMN) latency, P300 latency, Judson grade, and Hall grade.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>ds-TMS was associated with larger gains in consciousness (CRS-R scores) compared with DLPFC-rTMS in a retrospective cohort. Both interventions had comparable improvement in cognitive and somatosensory outcomes (MMN, P300, and Judson\/Hall grades). Higher CRS-R scores correlated with shorter MMN latency and better Hall grades.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>ds-TMS treatment may represent an effective therapeutic approach for DoC, with potential effects on consciousness recovery.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/21580014251392466","type":"journal-article","created":{"date-parts":[[2025,10,28]],"date-time":"2025-10-28T22:41:03Z","timestamp":1761691263000},"page":"331-338","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":2,"title":["Dual-Site Transcranial Magnetic Stimulation Improves Consciousness in Patients with Disorders of Consciousness"],"prefix":"10.1177","volume":"15","author":[{"given":"Lingyan","family":"Wang","sequence":"first","affiliation":[{"name":"Department of Rehabilitation Medicine, Jinhua Hospital of TCM, Zhejiang University of Traditional Chinese Medicine, Jinhua, China."}]},{"given":"Xuehan","family":"Zang","sequence":"additional","affiliation":[{"name":"Centre for Cognition and Brain Disorders, Hospital of Hangzhou Normal University, Hangzhou, China."}]},{"given":"Heliang","family":"Yang","sequence":"additional","affiliation":[{"name":"Department of Rehabilitation Medicine, Jinhua Hospital of TCM, Zhejiang University of Traditional Chinese Medicine, Jinhua, China."}]},{"given":"Qiwei","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Rehabilitation Medicine, Jinhua Hospital of TCM, Zhejiang University of Traditional Chinese Medicine, Jinhua, China."}]},{"given":"Ying","family":"Zhao","sequence":"additional","affiliation":[{"name":"Department of Rehabilitation Medicine, Jinhua Hospital of TCM, Zhejiang University of Traditional Chinese Medicine, Jinhua, China."}]},{"given":"Hong","family":"Hong","sequence":"additional","affiliation":[{"name":"Department of Rehabilitation Medicine, Jinhua Hospital of TCM, Zhejiang University of Traditional Chinese Medicine, Jinhua, China."}]},{"given":"Hangjie","family":"He","sequence":"additional","affiliation":[{"name":"Department of Rehabilitation Medicine, Jinhua Hospital of TCM, Zhejiang University of Traditional Chinese Medicine, Jinhua, China."}]},{"given":"Lijuan","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Rehabilitation Medicine, Jinhua Hospital of TCM, Zhejiang University of Traditional Chinese Medicine, Jinhua, China."}]},{"given":"Aiqun","family":"Shi","sequence":"additional","affiliation":[{"name":"Department of Rehabilitation Medicine, Jinhua Hospital of TCM, Zhejiang University of Traditional Chinese Medicine, Jinhua, China."}]},{"given":"Nantu","family":"Hu","sequence":"additional","affiliation":[{"name":"Zhejiang-Belgium Joint Laboratory for Disorders of Consciousness, Hangzhou Normal University, Hangzhou, China."},{"name":"International Unresponsive Wakefulness Syndrome and Consciousness Science Institute, Hangzhou Normal University, Hangzhou, China."}]},{"given":"Haibo","family":"Di","sequence":"additional","affiliation":[{"name":"Zhejiang-Belgium Joint Laboratory for Disorders of Consciousness, Hangzhou Normal University, Hangzhou, China."},{"name":"International Unresponsive Wakefulness Syndrome and Consciousness Science Institute, Hangzhou Normal University, Hangzhou, China."}]},{"given":"Jiasheng","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Rehabilitation Medicine, Jinhua Hospital of TCM, Zhejiang University of Traditional Chinese Medicine, Jinhua, China."}]},{"given":"Xianwei","family":"Che","sequence":"additional","affiliation":[{"name":"Centre for Cognition and Brain Disorders, Hospital of Hangzhou Normal University, Hangzhou, China."},{"name":"Zhejiang-Belgium Joint Laboratory for Disorders of Consciousness, Hangzhou Normal University, Hangzhou, China."},{"name":"International Unresponsive Wakefulness Syndrome and Consciousness Science Institute, Hangzhou Normal University, Hangzhou, China."}]}],"member":"179","published-online":{"date-parts":[[2026,1,19]]},"reference":[{"key":"e_1_3_3_2_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12311-016-0815-8"},{"key":"e_1_3_3_3_1","volume-title":"Categorical data analysis","author":"Agresti A","year":"2003","unstructured":"Agresti A. 2003. 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