{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,18]],"date-time":"2026-05-18T17:49:48Z","timestamp":1779126588255,"version":"3.51.4"},"reference-count":49,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[2026,2,1]],"date-time":"2026-02-01T00:00:00Z","timestamp":1769904000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"DOI":"10.13039\/501100019168","name":"Starship Foundation","doi-asserted-by":"crossref","award":["1562"],"award-info":[{"award-number":["1562"]}],"id":[{"id":"10.13039\/501100019168","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Games for Health Journal"],"published-print":{"date-parts":[[2026,2,1]]},"abstract":"<jats:sec>\n                    <jats:title>Objectives:<\/jats:title>\n                    <jats:p>This study was undertaken to investigate the comparative efficacy of a cognitive behavior therapy and biofeedback-based computer game (Starship Rescue: Vortex of Anxiety [SRVA]) and placebo well-being-focused computer game (Starship Rescue: Voyage of Wellness) for reducing symptoms of anxiety and improving quality of life among children and young people aged 8\u201318 with long-term physical conditions (LTPCs).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods:<\/jats:title>\n                    <jats:p>A randomized controlled trial was conducted with 60 participants (30 per arm). Primary outcomes were change in anxiety symptoms on the Generalized Anxiety Disorder 7-item (GAD-7) and Spence Children\u2019s Anxiety Scale (SCAS) at 4 weeks. Secondary outcomes were changes in anxiety symptoms at 3 months; changes in quality of life using the Pediatric Quality of Life Inventory (PedsQL) at 4 weeks and 3 months; and acceptability of SRVA recorded at 4 weeks.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>Participants in both groups experienced reduced anxiety (from a moderate to mild level) and improved quality of life at 4 weeks and 3 months. There were no significant group differences or time-by-group interactions observed for GAD-7, SCAS, or PedsQL. While SRVA was broadly acceptable, some suggestions for improvement of content and design were provided by users.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>Although this is the second study to demonstrate that SRVA can reduce levels of anxiety in children and young people with LTPC, previous questions regarding its efficacy and component-related benefits and new questions regarding the clinical value of physical health-oriented eHealth interventions remain unanswered. Further research is needed before SRVA can be recommended for clinical use.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/2161783x251361933","type":"journal-article","created":{"date-parts":[[2026,2,11]],"date-time":"2026-02-11T07:19:47Z","timestamp":1770794387000},"page":"42-49","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":1,"title":["Randomized Controlled Trial of Starship Rescue: A Cognitive Behavior Therapy and Biofeedback-Based Computer Game to Treat Anxiety in Children and Young People with Long-Term Physical Conditions"],"prefix":"10.1177","volume":"15","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8755-6217","authenticated-orcid":false,"given":"Hiran","family":"Thabrew","sequence":"first","affiliation":[{"name":"Psychological Medicine, University of Auckland, Auckland, New Zealand."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Harshali","family":"Kumar","sequence":"additional","affiliation":[{"name":"Psychological Medicine, University of Auckland, Auckland, New Zealand."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tarique","family":"Naseem","sequence":"additional","affiliation":[{"name":"Carbon Imagineering, Auckland, New Zealand."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chris","family":"Frampton","sequence":"additional","affiliation":[{"name":"Statistical Consultants Limited, Auckland, New Zealand."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Karolina","family":"Stasiak","sequence":"additional","affiliation":[{"name":"Psychological Medicine, University of Auckland, Auckland, New Zealand."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sally","family":"Merry","sequence":"additional","affiliation":[{"name":"Psychological Medicine, University of Auckland, Auckland, New Zealand."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2026,2,10]]},"reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.297.24.2741"},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.1192\/apt.3.4.204"},{"key":"e_1_3_3_4_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.297.24.2755"},{"key":"e_1_3_3_5_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2010.130"},{"key":"e_1_3_3_6_2","doi-asserted-by":"publisher","DOI":"10.1542\/pir.33-3-99"},{"key":"e_1_3_3_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.neubiorev.2009.10.002"},{"key":"e_1_3_3_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/s1056-4993(03)00024-5"},{"key":"e_1_3_3_9_2","doi-asserted-by":"publisher","DOI":"10.1097\/00004583-199712000-00022"},{"key":"e_1_3_3_10_2","doi-asserted-by":"publisher","DOI":"10.4088\/jcp.v60n0702"},{"key":"e_1_3_3_11_2","doi-asserted-by":"publisher","DOI":"10.1186\/1745-0179-1-18"},{"key":"e_1_3_3_12_2","doi-asserted-by":"publisher","DOI":"10.1017\/S0033291708003954"},{"key":"e_1_3_3_13_2","doi-asserted-by":"publisher","DOI":"10.1001\/archpsyc.55.1.56"},{"key":"e_1_3_3_14_2","doi-asserted-by":"publisher","DOI":"10.1136\/archdischild-2014-307474"},{"key":"e_1_3_3_15_2","doi-asserted-by":"publisher","DOI":"10.1037\/a0035458"},{"key":"e_1_3_3_16_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(07)61242-2"},{"key":"e_1_3_3_17_2","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.e2598"},{"issue":"1","key":"e_1_3_3_18_2","first-page":"187","article-title":"Use of the internet in the treatment of anxiety disorders with children and adolescents","volume":"5","author":"Holmes J","year":"2009","unstructured":"Holmes J, , March S, , Spence S. 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