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However, in cases of extensive or severe injury, the intrinsic repair mechanisms are often insufficient, underscoring the need for advanced therapeutic strategies to accelerate healing and minimize scar formation.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Recent Advances:<\/jats:title>\n                    <jats:p>Electrically conductive hydrogels (ECHs), combining the advantageous properties of hydrogels with the physiological and electrochemical characteristics of conductive materials, present a safer and more convenient alternative to traditional electrode-based electrical stimulation (ES) for treating chronic and nonhealing wounds. This review summarizes the various types of ECHs and their functional roles in facilitating wound healing.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Critical Issues:<\/jats:title>\n                    <jats:p>Understanding the mechanisms by which ECHs interact with electrical signals in the skin, along with precise control of the synergy between these signals and other functional properties, is critical for achieving optimal wound healing outcomes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Future Directions:<\/jats:title>\n                    <jats:p>Future development of ECHs should focus on elucidating underlying mechanisms, standardizing ES parameters, validating efficacy in clinically relevant animal models, and integrating multifunctional systems. Additionally, material design must be optimized for biocompatibility, adaptability, and scalability to facilitate clinical translation in chronic and nonhealing wound treatment.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/21621918251374285","type":"journal-article","created":{"date-parts":[[2025,9,11]],"date-time":"2025-09-11T08:33:32Z","timestamp":1757579612000},"page":"399-413","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":5,"title":["Electrically Conductive Hydrogels for Wound Healing"],"prefix":"10.1177","volume":"15","author":[{"given":"Lulu","family":"Sun","sequence":"first","affiliation":[{"name":"Beijing Laboratory of Biomedical Materials, State Key Laboratory of Organic\u2010Inorganic Composites, Beijing University of Chemical Technology, Beijing, PR China."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ruinan","family":"Hao","sequence":"additional","affiliation":[{"name":"Beijing Laboratory of Biomedical Materials, State Key Laboratory of Organic\u2010Inorganic Composites, Beijing University of Chemical Technology, Beijing, PR China."},{"name":"School of Medicine, South China University of Technology, Guangzhou, PR China."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kelly","family":"Van Van","sequence":"additional","affiliation":[{"name":"School of Science, The University of Hong Kong, Hong Kong, PR China."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Feng","family":"Tian","sequence":"additional","affiliation":[{"name":"Beijing Laboratory of Biomedical Materials, State Key Laboratory of Organic\u2010Inorganic Composites, Beijing University of Chemical Technology, Beijing, PR China."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7209-7935","authenticated-orcid":false,"given":"Jiajia","family":"Xue","sequence":"additional","affiliation":[{"name":"Beijing Laboratory of Biomedical Materials, State Key Laboratory of Organic\u2010Inorganic Composites, Beijing University of Chemical Technology, Beijing, PR China."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2025,9,10]]},"reference":[{"key":"e_1_3_4_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.bioactmat.2020.03.010"},{"key":"e_1_3_4_3_2","doi-asserted-by":"publisher","DOI":"10.1038\/nature07039"},{"key":"e_1_3_4_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.semcdb.2008.12.009"},{"key":"e_1_3_4_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbagen.2016.03.023"},{"issue":"4","key":"e_1_3_4_6_2","first-page":"112","article-title":"Bio-electrical stimulation therapy using POSiFECT\u00aeRD","volume":"2","author":"Morris C","year":"2006","unstructured":"Morris C. 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