{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T18:14:03Z","timestamp":1777659243775,"version":"3.51.4"},"reference-count":20,"publisher":"SAGE Publications","issue":"3_suppl","license":[{"start":{"date-parts":[[2017,9,1]],"date-time":"2017-09-01T00:00:00Z","timestamp":1504224000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Global Spine Journal"],"published-print":{"date-parts":[[2017,9]]},"abstract":"<jats:p>The Institute of Medicine defines clinical practice guidelines as \u201cstatements that include recommendations intended to optimize patient care that are informed by a systematic review of evidence and an assessment of the benefits and harms of alternative care options.\u201d Guidelines help clinicians implement best evidence into practice and encourage informed shared decision making with patients. Guidelines are intended to enhance the quality of patient care by discouraging ineffective and potentially harmful interventions and standardizing practice. Standards for the development and appraisal of guidelines, such as those proposed by the Institute of Medicine and other organizations, help assure guideline quality and credibility. Primary standards include establishing transparency, managing conflicts of interest, forming a multidisciplinary guideline development group, conducting methodologically sound systematic reviews, developing evidence-based recommendations, balancing risks and harms, and rating the strength of recommendations based on the confidence in the evidence. Furthermore, the guideline document must be appraised internally and externally and updated when new evidence arises. The Grading of Recommendation, Assessment, Development and Evaluation process helps appraise the existing body of evidence as well as provide an interactive framework for weighing the benefits and harms of treatment options and translating evidence to recommendations. This article summarizes the methodology used to develop clinical practice guidelines for the management of degenerative cervical myelopathy and acute spinal cord injury.<\/jats:p>","DOI":"10.1177\/2192568217701715","type":"journal-article","created":{"date-parts":[[2017,9,5]],"date-time":"2017-09-05T11:04:01Z","timestamp":1504609441000},"page":"8S-20S","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":22,"title":["Guidelines for the Management of Degenerative Cervical Myelopathy and Acute Spinal Cord Injury: Development Process and Methodology"],"prefix":"10.1177","volume":"7","author":[{"given":"Lindsay A.","family":"Tetreault","sequence":"first","affiliation":[{"name":"Toronto Western Hospital, University Health Network, Toronto, Ontario, Canada"},{"name":"University College Cork, Cork, Ireland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrea C.","family":"Skelly","sequence":"additional","affiliation":[{"name":"Spectrum Research, Inc, Tacoma, WA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joseph R.","family":"Dettori","sequence":"additional","affiliation":[{"name":"Spectrum Research, Inc, Tacoma, WA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jefferson R.","family":"Wilson","sequence":"additional","affiliation":[{"name":"University of Toronto, Toronto, Ontario, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Allan R.","family":"Martin","sequence":"additional","affiliation":[{"name":"Toronto Western Hospital, University Health Network, Toronto, Ontario, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael G.","family":"Fehlings","sequence":"additional","affiliation":[{"name":"Toronto Western Hospital, University Health Network, Toronto, Ontario, Canada"},{"name":"University of Toronto, Toronto, Ontario, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2017,9,5]]},"reference":[{"key":"bibr1-2192568217701715","doi-asserted-by":"publisher","DOI":"10.17226\/13058"},{"key":"bibr2-2192568217701715","doi-asserted-by":"publisher","DOI":"10.1177\/0194599812467004"},{"key":"bibr3-2192568217701715","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-139-6-200309160-00013"},{"key":"bibr4-2192568217701715","doi-asserted-by":"publisher","DOI":"10.5694\/j.1326-5377.2011.tb03184.x"},{"key":"bibr5-2192568217701715","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0025153"},{"key":"bibr6-2192568217701715","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-156-7-201204030-00009"},{"key":"bibr7-2192568217701715","first-page":"159","volume":"107","author":"Shiffman RN","year":"2004","journal-title":"Stud Health Technol Inform"},{"key":"bibr8-2192568217701715","volume-title":"Methods Guide for Effectiveness and Comparative Effectiveness Reviews (AHRQ Publication No. 10(14)-EHC063-EF)","author":"Agency for Healthcare Research and Quality","year":"2013"},{"key":"bibr9-2192568217701715","doi-asserted-by":"publisher","DOI":"10.1016\/j.jclinepi.2010.07.015"},{"key":"bibr10-2192568217701715","doi-asserted-by":"publisher","DOI":"10.1007\/s00776-005-0953-1"},{"key":"bibr11-2192568217701715","unstructured":"Patient-Centered Outcomes Research Institute. 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