{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,4]],"date-time":"2026-09-04T05:55:50Z","timestamp":1788501350835,"version":"build-2803163510"},"reference-count":31,"publisher":"SAGE Publications","issue":"7","license":[{"start":{"date-parts":[[2021,2,5]],"date-time":"2021-02-05T00:00:00Z","timestamp":1612483200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Global Spine Journal"],"published-print":{"date-parts":[[2022,9]]},"abstract":"<jats:sec>\n                    <jats:title>Study Design:<\/jats:title>\n                    <jats:p>Cross-sectional study.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objectives:<\/jats:title>\n                    <jats:p>Thus, this study aimed to assess the epidemiological profile of a patient sample that underwent spinal surgery regarding their nutritional and vitamin D status.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>Serum albumin and vitamin D (25-hydroxyvitamin D) levels were measured in patients with different spinal surgical approaches and various pathologies at a single institution. 112 patients were retrospectively identified for inclusion and stratified by age into 4 age groups and by pathology. The nutritional status of the patients was classified in vitamin D inadequacy (&lt; 30ng\/mL), vitamin D deficiency (&lt;20ng\/mL), and hypoalbuminemia (&lt;3.5g\/dL). Data was analyzed comparing vitamin D, and albumin means considering gender, age group, and pathologies.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>Twenty-eight (25.2%) patients had hypoalbuminemia. There was no difference between gender (p = 0.988); there was a significant decrease in albumin concentration increasing the age (p &lt; 0.001). The prevalence of hypoalbuminemia was significantly higher in patients with trauma, tumor and infection than in those patients with degenerative and deformity diseases (p = 0.003). The prevalence of vitamin D inadequacy was 33.7%, and that of deficiency was 62.2%, while severe deficiency (&lt; 10 ng\/mL) in 16.3%. The vitamin D concentration was significantly different among the pathologies (P = 0.047), the lower concentration occurring in patients with tumor.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>Older patients, as well as patients with tumor and infectious pathologies, seem to have a higher prevalence of hypoalbuminemia, inferring malnutrition. There was a low epidemic level of vitamin D concentration, almost all patients presenting some degree of hypovitaminosis D, independent of age, gender and nutritional status.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/2192568220982561","type":"journal-article","created":{"date-parts":[[2021,2,9]],"date-time":"2021-02-09T03:56:08Z","timestamp":1612842968000},"page":"1468-1474","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":6,"title":["Age and Spinal Disease Correlate to Albumin and Vitamin D Status"],"prefix":"10.1177","volume":"12","author":[{"given":"Anderson Gomes","family":"Marin","sequence":"first","affiliation":[{"name":"Department of Orthopedics and Anesthesiology, University of Sao Paulo, School of Medicine, Ribeir\u00e3o Preto, S\u00e3o Paulo, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Raphael de Rezende","family":"Pratali","sequence":"additional","affiliation":[{"name":"Hospital do Servidor P\u00fablico Estadual, S\u00e3o Paulo, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Samuel Machado","family":"Marin","sequence":"additional","affiliation":[{"name":"Hospital do Servidor P\u00fablico Estadual, S\u00e3o Paulo, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3387-4797","authenticated-orcid":false,"given":"Carlos Fernando Pereira da Silva","family":"Herrero","sequence":"additional","affiliation":[{"name":"Department of Orthopedics and Anesthesiology, University of Sao Paulo, School of Medicine, Ribeir\u00e3o Preto, S\u00e3o Paulo, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2021,2,5]]},"reference":[{"key":"bibr1-2192568220982561","doi-asserted-by":"publisher","DOI":"10.1016\/j.spinee.2013.02.071"},{"key":"bibr2-2192568220982561","doi-asserted-by":"publisher","DOI":"10.1097\/00007632-199208001-00017"},{"key":"bibr3-2192568220982561","doi-asserted-by":"publisher","DOI":"10.1097\/00007632-199520120-00006"},{"key":"bibr4-2192568220982561","doi-asserted-by":"publisher","DOI":"10.1097\/00007632-199611150-00018"},{"key":"bibr5-2192568220982561","doi-asserted-by":"publisher","DOI":"10.1007\/s00586-014-3622-2"},{"key":"bibr6-2192568220982561","doi-asserted-by":"publisher","DOI":"10.1097\/BRS.0000000000001551"},{"key":"bibr7-2192568220982561","doi-asserted-by":"publisher","DOI":"10.2106\/00004623-198264090-00001"},{"key":"bibr8-2192568220982561","doi-asserted-by":"publisher","DOI":"10.1054\/clnu.2001.0438"},{"key":"bibr9-2192568220982561","doi-asserted-by":"publisher","DOI":"10.1177\/000313481708301123"},{"key":"bibr10-2192568220982561","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMra070553"},{"key":"bibr11-2192568220982561","doi-asserted-by":"publisher","DOI":"10.1097\/BRS.0b013e3182739ad1"},{"key":"bibr12-2192568220982561","doi-asserted-by":"publisher","DOI":"10.1007\/s00586-010-1385-y"},{"key":"bibr13-2192568220982561","doi-asserted-by":"publisher","DOI":"10.1016\/j.spinee.2010.09.024"},{"key":"bibr14-2192568220982561","doi-asserted-by":"publisher","DOI":"10.1155\/2013\/471695"},{"key":"bibr15-2192568220982561","doi-asserted-by":"publisher","DOI":"10.1016\/j.jspd.2017.03.008"},{"key":"bibr16-2192568220982561","doi-asserted-by":"publisher","DOI":"10.1097\/BRS.0b013e31820cccfb"},{"key":"bibr17-2192568220982561","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-019-44373-2"},{"key":"bibr18-2192568220982561","doi-asserted-by":"publisher","DOI":"10.1097\/00003086-198809000-00002"},{"key":"bibr19-2192568220982561","doi-asserted-by":"publisher","DOI":"10.5312\/wjo.v7.i11.726"},{"key":"bibr20-2192568220982561","doi-asserted-by":"publisher","DOI":"10.1097\/BRS.0000000000001591"},{"key":"bibr21-2192568220982561","doi-asserted-by":"publisher","DOI":"10.1016\/j.bone.2006.09.026"},{"key":"bibr22-2192568220982561","doi-asserted-by":"publisher","DOI":"10.1001\/jama.281.16.1505"},{"key":"bibr23-2192568220982561","doi-asserted-by":"publisher","DOI":"10.1097\/00007632-199009000-00012"},{"key":"bibr24-2192568220982561","doi-asserted-by":"publisher","DOI":"10.5435\/00124635-200303000-00005"},{"key":"bibr25-2192568220982561","doi-asserted-by":"publisher","DOI":"10.1097\/00002517-199306060-00007"},{"key":"bibr26-2192568220982561","doi-asserted-by":"publisher","DOI":"10.1093\/ajcn\/84.1.18"},{"key":"bibr27-2192568220982561","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2004-2364"},{"key":"bibr28-2192568220982561","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMcp1009570"},{"key":"bibr29-2192568220982561","unstructured":"National Health and Nutrition Examination Survey. 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