{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T10:34:30Z","timestamp":1782902070142,"version":"3.54.5"},"reference-count":24,"publisher":"SAGE Publications","issue":"8","license":[{"start":{"date-parts":[[2021,2,16]],"date-time":"2021-02-16T00:00:00Z","timestamp":1613433600000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Global Spine Journal"],"published-print":{"date-parts":[[2022,10]]},"abstract":"<jats:sec>\n                    <jats:title>Study Design:<\/jats:title>\n                    <jats:p>Retrospective multicenter.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objectives:<\/jats:title>\n                    <jats:p>diffuse idiopathic skeletal hyperostosis (DISH) involving the cervical spine is a rare condition determining disabling aero-digestive symptoms. We analyzed impact of preoperative settings and intraoperative techniques on outcome of patients undergoing surgery for DISH.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>Patients with DISH needing for anterior cervical osteophytectomy were collected. Swallow studies and endoscopy supported imaging in targeting bone decompression. Patients characteristics, clinico-radiological presentation, outcome and surgical strategies were recorded. Impact on clinical outcome of duration and time to surgery and different surgical techniques was evaluated through ANOVA.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>24 patients underwent surgery. No correlation was noted between specific spinal levels affected by DISH and severity of pre-operative dysphagia. A trend toward a full clinical improvement was noted preferring the chisel ( P = 0.12) to the burr ( P = 0.65), and whenever C2-C3 was decompressed, whether hyperostosis included that level ( P = 0.15). Use of curved chisel reduced the surgical times ( P = 0.02) and, together with the nasogastric tube, the risk of complications, while bone removal involving 3 levels or more ( P = 0.04) and shorter waiting times for surgery ( P &lt; 0.001) positively influenced a complete swallowing recovery. Early decompressions were preferred, resulting in 66.6% of patients reporting disappearance of symptoms within 7 days. One and two recurrences respectively at clinical and radiological follow-up were registered 18-30 months after surgery.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>The \u201cage of DISH\u201d counts more than patients\u2019 age with timeliness of decompression being crucial in determining clinical outcome even with a preoperative mild dysphagia. Targeted bone resections could be reasonable in elderly patients, while in younger ones more extended decompressions should be preferred.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/2192568220988272","type":"journal-article","created":{"date-parts":[[2021,2,20]],"date-time":"2021-02-20T20:03:03Z","timestamp":1613851383000},"page":"1751-1760","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":15,"title":["Surgical Treatment of Diffuse Idiopathic Skeletal Hyperostosis (DISH) Involving the Cervical Spine: Technical Nuances and Outcome of a Multicenter Experience"],"prefix":"10.1177","volume":"12","author":[{"given":"Giorgio","family":"Lofrese","sequence":"first","affiliation":[{"name":"Neurosurgery Division, \u201cM. Bufalini\u201d Hospital, Cesena, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8607-5323","authenticated-orcid":false,"given":"Alba","family":"Scerrati","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, S. Anna University Hospital, Ferrara, Italy"},{"name":"Department of Morphology, Surgery and Experimental Medicine, University of Ferrara, Ferrara, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Massimo","family":"Balsano","sequence":"additional","affiliation":[{"name":"Regional Spinal Department, UOC Ortopedia A, AOUI, Verona, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roberto","family":"Bassani","sequence":"additional","affiliation":[{"name":"Spine Surgery II, IRCCS Istituto Ortopedico Galeazzi, Milan, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michele","family":"Cappuccio","sequence":"additional","affiliation":[{"name":"Department of Spine Surgery, Ospedale Maggiore \u201cC.A. Pizzardi,\u201d Bologna, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michele A.","family":"Cavallo","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, S. Anna University Hospital, Ferrara, Italy"},{"name":"Department of Morphology, Surgery and Experimental Medicine, University of Ferrara, Ferrara, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5100-7478","authenticated-orcid":false,"given":"Fabio","family":"Cofano","sequence":"additional","affiliation":[{"name":"Department of Neuroscience \u201cRita Levi Montalcini,\u201d Neurosurgery Unit, University of Turin, Turin, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francesco","family":"Cultrera","sequence":"additional","affiliation":[{"name":"Neurosurgery Division, \u201cM. Bufalini\u201d Hospital, Cesena, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Federico","family":"De Iure","sequence":"additional","affiliation":[{"name":"Department of Spine Surgery, Ospedale Maggiore \u201cC.A. Pizzardi,\u201d Bologna, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francesco Di","family":"Biase","sequence":"additional","affiliation":[{"name":"Department of Neurologic Surgery, San Carlo Hospital, Potenza, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roberto","family":"Donati","sequence":"additional","affiliation":[{"name":"Neurosurgery Division, \u201cM. Bufalini\u201d Hospital, Cesena, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Diego","family":"Garbossa","sequence":"additional","affiliation":[{"name":"Department of Neuroscience \u201cRita Levi Montalcini,\u201d Neurosurgery Unit, University of Turin, Turin, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marta","family":"Menegatti","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, S. Anna University Hospital, Ferrara, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alessandro","family":"Olivi","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy"},{"name":"Department of Neuroscience, Neurosurgery Section, Universit\u00e0 Cattolica del Sacro Cuore, Rome, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9306-0242","authenticated-orcid":false,"given":"Giorgio","family":"Palandri","sequence":"additional","affiliation":[{"name":"Department of Neurologic Surgery, Institute of Neurological Sciences of Bologna IRCCS, Bologna, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antonino","family":"Raco","sequence":"additional","affiliation":[{"name":"UOC di Neurochirurgia, Azienda Ospedaliera Sant\u2019Andrea, Sapienza, Roma, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luca","family":"Ricciardi","sequence":"additional","affiliation":[{"name":"UO di Neurochirurgia, Pia Fondazione di Culto e Religione Cardinal G. Panico, Tricase, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giannantonio","family":"Spena","sequence":"additional","affiliation":[{"name":"Neurosurgery Unit, Ospedale Alessandro Manzoni, Lecco, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8708-255X","authenticated-orcid":false,"given":"Luigino","family":"Tosatto","sequence":"additional","affiliation":[{"name":"Neurosurgery Division, \u201cM. Bufalini\u201d Hospital, Cesena, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jacopo","family":"Visani","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, S. Anna University Hospital, Ferrara, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Massimiliano","family":"Visocchi","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy"},{"name":"Department of Neuroscience, Neurosurgery Section, Universit\u00e0 Cattolica del Sacro Cuore, Rome, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gianluigi","family":"Zona","sequence":"additional","affiliation":[{"name":"Section of Neurosurgery, IRCCS Ospedale Policlinico San Martino, Genoa, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pasquale","family":"De Bonis","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, S. 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