{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T02:16:56Z","timestamp":1787019416653,"version":"build-2736575974"},"reference-count":17,"publisher":"SAGE Publications","issue":"4","license":[{"start":{"date-parts":[[2022,11,1]],"date-time":"2022-11-01T00:00:00Z","timestamp":1667260800000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Global Spine Journal"],"published-print":{"date-parts":[[2024,5]]},"abstract":"<jats:sec>\n                    <jats:title>Study Design<\/jats:title>\n                    <jats:p>Retrospective Cohort Study<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>Cervical radiculopathy and peripheral entrapment neuropathies often have overlapping symptoms that are difficult to distinguish on physical examination. Small-scale studies have attempted to report the incidence of this phenomenon, often called double crush syndrome (DCS), with varying results. The present study aims to determine the incidence of concomitant cervical radiculopathy and peripheral nerve compression and to determine if the DCS hypothesis, which states that compression of a nerve at one site leaves it more susceptible to compression at another, is valid.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>The PearlDiver database was queried from 2010 to 2020. The incidence of peripheral neuropathy in cervical radiculopathy was assessed. Propensity score matching was used to determine if patients with cervical radiculopathy were more likely to have peripheral nerve compression compared to controls, and vice versa, to test the DCS hypothesis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>The database contains records of 90,772\u00a0632 patients. The incidence of carpal tunnel syndrome (CTS) or peripheral ulnar nerve compression (PUnC) in cervical radiculopathy was 9.98% and 3.15%, respectively. The incidence of both carpal tunnel syndrome and PUnC in cervical radiculopathy was 1.84%. Patients with cervical radiculopathy were more likely than matched controls to have both CTS ( P &lt; .001) and PUnC ( P &lt; .001). Patients with CTS ( P &lt; .001) and with PUnC ( P &lt; .001) were more likely to have cervical radiculopathy than the control cohort.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>The incidence of DCS is reported. Patients with cervical radiculopathy are more likely than matched controls to have peripheral nerve compression, and vice versa, in support of the DCS hypothesis.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/21925682221137530","type":"journal-article","created":{"date-parts":[[2022,11,2]],"date-time":"2022-11-02T02:33:35Z","timestamp":1667356415000},"page":"1220-1226","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":8,"title":["The Incidence of Double Crush Syndrome in Surgically Treated Patients"],"prefix":"10.1177","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1777-2969","authenticated-orcid":false,"given":"Emily S.","family":"Mills","sequence":"first","affiliation":[{"name":"Department of Orthopaedic Surgery, Keck School of Medicine at The University of Southern California, Los Angeles, CA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9400-2247","authenticated-orcid":false,"given":"Kevin","family":"Mertz","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery, Keck School of Medicine at The University of Southern California, Los Angeles, CA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zoe","family":"Fresquez","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery, Keck School of Medicine at The University of Southern California, Los Angeles, CA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8891-0353","authenticated-orcid":false,"given":"Andy","family":"Ton","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery, Keck School of Medicine at The University of Southern California, Los Angeles, CA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5680-0643","authenticated-orcid":false,"given":"Zorica","family":"Buser","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery, Keck School of Medicine at The University of Southern California, Los Angeles, CA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5919-707X","authenticated-orcid":false,"given":"Ram K.","family":"Alluri","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery, Keck School of Medicine at The University of Southern California, Los Angeles, CA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7513-3519","authenticated-orcid":false,"given":"Raymond J.","family":"Hah","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery, Keck School of Medicine at The University of Southern California, Los Angeles, CA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2022,11,1]]},"reference":[{"key":"bibr1-21925682221137530","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(73)93196-6"},{"key":"bibr2-21925682221137530","doi-asserted-by":"publisher","DOI":"10.1097\/00000637-199103000-00008"},{"key":"bibr3-21925682221137530","doi-asserted-by":"publisher","DOI":"10.1016\/S0363-5023(87)80207-1"},{"key":"bibr4-21925682221137530","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1097-4598(199901)22:1<71::AID-MUS11>3.0.CO;2-S"},{"key":"bibr5-21925682221137530","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.49.1.21"},{"key":"bibr6-21925682221137530","doi-asserted-by":"publisher","DOI":"10.1016\/j.clinph.2006.02.013"},{"key":"bibr7-21925682221137530","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuchi.2020.09.011"},{"key":"bibr8-21925682221137530","doi-asserted-by":"publisher","DOI":"10.1007\/s00296-010-1746-1"},{"key":"bibr9-21925682221137530","doi-asserted-by":"publisher","DOI":"10.1007\/s004150050401"},{"key":"bibr10-21925682221137530","doi-asserted-by":"publisher","DOI":"10.1016\/j.clineuro.2007.08.013"},{"key":"bibr11-21925682221137530","doi-asserted-by":"publisher","DOI":"10.1038\/sj.sc.3100539"},{"issue":"2","key":"bibr12-21925682221137530","first-page":"119","volume":"27","author":"Baba M","year":"1987","journal-title":"Electromyogr Clin Neurophysiol"},{"key":"bibr13-21925682221137530","doi-asserted-by":"publisher","DOI":"10.1097\/00005650-199801000-00004"},{"key":"bibr14-21925682221137530","doi-asserted-by":"publisher","DOI":"10.1159\/000328672"},{"key":"bibr15-21925682221137530","doi-asserted-by":"publisher","DOI":"10.1007\/s10143-009-0219-z"},{"key":"bibr16-21925682221137530","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.50.1.78"},{"key":"bibr17-21925682221137530","doi-asserted-by":"publisher","DOI":"10.1016\/S0030-5898(20)32081-2"}],"container-title":["Global Spine Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/21925682221137530","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/21925682221137530","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/21925682221137530","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T07:19:14Z","timestamp":1777447154000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/21925682221137530"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,11,1]]},"references-count":17,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2024,5]]}},"alternative-id":["10.1177\/21925682221137530"],"URL":"https:\/\/doi.org\/10.1177\/21925682221137530","relation":{},"ISSN":["2192-5682","2192-5690"],"issn-type":[{"value":"2192-5682","type":"print"},{"value":"2192-5690","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,11,1]]}}}