{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T09:44:46Z","timestamp":1787737486691,"version":"build-2784847793"},"reference-count":17,"publisher":"SAGE Publications","issue":"1_suppl","license":[{"start":{"date-parts":[[2023,4,1]],"date-time":"2023-04-01T00:00:00Z","timestamp":1680307200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Global Spine Journal"],"published-print":{"date-parts":[[2023,4]]},"abstract":"<jats:sec>\n                    <jats:title>Study Design<\/jats:title>\n                    <jats:p>Multicenter prospective cohort study<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To analyse therapeutical strategies applied to osteoporotic thoracolumbar OF 4 injuries, to assess related complications and clinical outcome.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A multicenter prospective cohort study (EOFTT) including 518 consecutive patients who were treated for an Osteoporotic vertebral compression fracture (OVCF). For the present study, only patients with OF 4 fractures were analysed. Outcome parameters were complications, Visual Analogue Scale, Oswestry Disability Questionnaire, Timed Up &amp; Go test, EQ-5D 5L, and Barthel Index after a minimum follow-up of 6\u00a0weeks.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>A total of 152 (29%) patients presented with OF 4 fractures with a mean age of 76\u00a0years (range 41-97). The most common treatment was short-segment posterior stabilization (51%; hybrid stabilization in 36%). Mean follow up was 208 days (\u00b1131\u00a0days), mean ODI was 30 \u00b1 21. Dorsoventral stabilized patients were younger compared to the other groups ( P &lt; .001) and had significant better TuG compared to hybrid stabilization ( P = .049). The other clinical outcomes did not differ in the therapy strategies (VAS pain: P = 1.000, ODI: P &gt; .602, Barthel: P &gt; .252, EQ-5D 5L index value: P &gt; .610, VAS-EQ-5D 5L: P = 1.000). The inpatient complication rate was 8% after conservative and 16% after surgical treatment. During follow-up period 14% of conservatively treated patients and 3% of surgical treated patients experienced neurological deficits.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Conservative therapy of OF 4 injuries seems to be viable option in patients with only moderate symptoms. Hybrid stabilization was the dominant treatment strategy leading to promising clinical short-term results. Stand-alone cement augmentation seems to be a valid alternative in selected cases.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/21925682221140831","type":"journal-article","created":{"date-parts":[[2023,4,21]],"date-time":"2023-04-21T16:08:58Z","timestamp":1682093338000},"page":"36S-43S","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":14,"title":["Treatment and Outcome of Osteoporotic Thoracolumbar Vertebral Body Fractures With Deformation of Both Endplates With or Without Posterior Wall Involvement (OF 4): Short-Term Results from the Prospective EOFTT Multicenter Study"],"prefix":"10.1177","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5179-4192","authenticated-orcid":false,"given":"Ulrich J. A.","family":"Spiegl","sequence":"first","affiliation":[{"name":"Department of Orthopaedics, Trauma and Plastic Surgery, University Hospital Leipzig, Leipzig, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Philipp","family":"Schenk","sequence":"additional","affiliation":[{"name":"Department of Science, Research and Education, BG Clinic Bergmannstrost Halle, Halle, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Klaus John","family":"Schnake","sequence":"additional","affiliation":[{"name":"Center for Spinal and Scoliosis Surgery, Malteser Waldkrankenhaus St. Marien, Erlangen, Germany"},{"name":"Department of Orthopedics and Traumatology, Paracelsus Private Medical University Nuremberg, Nuremberg, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8748-1190","authenticated-orcid":false,"given":"Bernhard W.","family":"Ullrich","sequence":"additional","affiliation":[{"name":"Department of Trauma, Hand and Reconstructive Surgery, University Hospital Jena, Jena, Germany"},{"name":"Department of Trauma and Reconstructive Surgery, BG Clinic Bergmannstrost Halle, Halle, German"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5051-0998","authenticated-orcid":false,"given":"Georg","family":"Osterhoff","sequence":"additional","affiliation":[{"name":"Department of Orthopaedics, Trauma and Plastic Surgery, University Hospital Leipzig, Leipzig, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1392-3990","authenticated-orcid":false,"given":"Max J.","family":"Scheyerer","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic and Traumatology, Faculty of Medicine and University Hospital Cologne, Cologne, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gregor","family":"Schmeiser","sequence":"additional","affiliation":[{"name":"Department of Spine Surgery, Schoen-Klinik Hamburg-Eilbek, Hamburg, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martin","family":"B\u00e4umlein","sequence":"additional","affiliation":[{"name":"Center for Orthopaedics and Trauma Surgery, University Hospital Giessen and Marburg GmbH, Marburg, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael A.","family":"Scherer","sequence":"additional","affiliation":[{"name":"Lehrk\u00f6rper Medizinische Fakult\u00e4t der, Technischen Universit\u00e4t M\u00fcnchen (Med. Fak. TUM), Munich, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"M\u00fcller","sequence":"additional","affiliation":[{"name":"Department of Orthopedic and Trauma Surgery, University Medical Center Schleswig-Holstein, Campus Kiel, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5921-8272","authenticated-orcid":false,"given":"Kai","family":"Sprengel","sequence":"additional","affiliation":[{"name":"University of Lucerne, Hirslanden Clinic St. Anna, Lucerne, Switzerland"},{"name":"Department of Trauma, University Hospital Zurich (USZ), University of Zurich (UZH), Zurich, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katja","family":"Liepold","sequence":"additional","affiliation":[{"name":"Department of Spine Surgery, Thuringia Clinic \u201cGeorgius Agricola\u201d Saalfeld, Teaching Hospital of the University of Jena, Saalfeld, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Simon","family":"Schramm","sequence":"additional","affiliation":[{"name":"Department of Trauma Surgery, University Hospital Erlangen, Erlangen, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H.-Christopher","family":"Baron","sequence":"additional","affiliation":[{"name":"Department for Paraplegia and Spine Surgery, BG Trauma Center, Tuebingen, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Holger","family":"Siekmann","sequence":"additional","affiliation":[{"name":"Clinic of Trauma-, Hand- and Reconstruction Surgery,AMEOS-Clinic Halberstadt, Halberstadt, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Falko","family":"Schwarz","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, - Friedrich Schiller University, Jena University Hospital, Jena, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alex","family":"Franck","sequence":"additional","affiliation":[{"name":"Department of Orthopaedics and Trauma Surgery, Regiomed Klinikum Coburg, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Volker","family":"Zimmermann","sequence":"additional","affiliation":[{"name":"Department of Trauma and Orthopedic Surgery, Klinikum Traunstein, Traunstein, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sebastian","family":"Katscher","sequence":"additional","affiliation":[{"name":"Interdisciplinary Center for Spine and Neurotrauma, Sana Klinikum Borna, Borna, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"Working Group Osteoporotic Fractures of the Spine Section of the German Society of Orthopaedics and Trauma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2023,4,21]]},"reference":[{"key":"bibr1-21925682221140831","doi-asserted-by":"publisher","DOI":"10.1177\/2192568217745823"},{"key":"bibr2-21925682221140831","doi-asserted-by":"publisher","DOI":"10.1177\/2192568217717972"},{"key":"bibr3-21925682221140831","doi-asserted-by":"publisher","DOI":"10.1177\/2192568217699209"},{"key":"bibr4-21925682221140831","doi-asserted-by":"publisher","DOI":"10.1177\/2192568220964051"},{"key":"bibr5-21925682221140831","doi-asserted-by":"publisher","DOI":"10.1007\/s00586-019-05957-8"},{"key":"bibr6-21925682221140831","doi-asserted-by":"publisher","DOI":"10.3238\/arztebl.m2021.0295"},{"key":"bibr7-21925682221140831","doi-asserted-by":"publisher","DOI":"10.1177\/2192568218771668"},{"key":"bibr8-21925682221140831","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD008618.pub3"},{"key":"bibr9-21925682221140831","doi-asserted-by":"publisher","DOI":"10.1055\/s-0038-1673537"},{"key":"bibr10-21925682221140831","doi-asserted-by":"publisher","DOI":"10.2106\/JBJS.J.00160"},{"key":"bibr11-21925682221140831","doi-asserted-by":"publisher","DOI":"10.1177\/2192568220982279"},{"key":"bibr12-21925682221140831","doi-asserted-by":"publisher","DOI":"10.1007\/s00586-020-06491-8"},{"key":"bibr13-21925682221140831","doi-asserted-by":"publisher","DOI":"10.1186\/s13018-015-0172-1"},{"key":"bibr14-21925682221140831","doi-asserted-by":"publisher","DOI":"10.1007\/s00068-020-01560-5"},{"key":"bibr15-21925682221140831","doi-asserted-by":"publisher","DOI":"10.1007\/s00402-018-2993-y"},{"key":"bibr16-21925682221140831","doi-asserted-by":"publisher","DOI":"10.22603\/ssrr.2019-0004"},{"key":"bibr17-21925682221140831","doi-asserted-by":"publisher","DOI":"10.1177\/2192568218818164"}],"container-title":["Global Spine Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/21925682221140831","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/21925682221140831","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/21925682221140831","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T07:14:37Z","timestamp":1777446877000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/21925682221140831"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,4]]},"references-count":17,"journal-issue":{"issue":"1_suppl","published-print":{"date-parts":[[2023,4]]}},"alternative-id":["10.1177\/21925682221140831"],"URL":"https:\/\/doi.org\/10.1177\/21925682221140831","relation":{},"ISSN":["2192-5682","2192-5690"],"issn-type":[{"value":"2192-5682","type":"print"},{"value":"2192-5690","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,4]]}}}