{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T05:02:47Z","timestamp":1791349367000,"version":"4.3.1"},"reference-count":28,"publisher":"SAGE Publications","issue":"8","license":[{"start":{"date-parts":[[2023,5,6]],"date-time":"2023-05-06T00:00:00Z","timestamp":1683331200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"crossref","award":["82072479, 81772381, 81874031"],"award-info":[{"award-number":["82072479, 81772381, 81874031"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"crossref"}]},{"name":"Talent Incubation Foundation of Peking University Third Hospital","award":["Y77477-03"],"award-info":[{"award-number":["Y77477-03"]}]},{"DOI":"10.13039\/501100002858","name":"China Postdoctoral Science Foundation","doi-asserted-by":"crossref","award":["2022M720293"],"award-info":[{"award-number":["2022M720293"]}],"id":[{"id":"10.13039\/501100002858","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Global Spine Journal"],"published-print":{"date-parts":[[2024,11]]},"abstract":"<jats:sec>\n                    <jats:title>Study Design<\/jats:title>\n                    <jats:p>Retrospective cohort study<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>To describe the clinical characteristics and surgical outcomes of patients with multilevel-ossification of the posterior longitudinal ligament (mT-OPLL), and to identify risk factors for unfavorable outcomes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Patients who were diagnosed with mT-OPLL and underwent one-stage thoracic posterior laminectomy combined with selective OPLL resection, spinal cord de-tension, and fusion surgery between August 2012 and October 2020 were recruited. Patients\u2019 demographic-, surgical- and radiological-related parameters were collected and analyzed. Neurological status was evaluated with mJOA score, and recovery rate (RR) was calculated using the Hirabayashi formula. According to RR, patients were divided into a favorable outcome group (FOG, RR \u226550%) and an unfavorable outcome group (UOG, RR &lt;50%). Univariate and multivariate analyses were used to compare the difference between the 2 groups and to identify risk factors for unfavorable outcomes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>A total of 83 patients were included, with an average age of 50.6 \u00b1 8.3 years. Cerebrospinal fluid leakage (60.2%) and transient neurological deterioration (9.6%) were the most common complications. The average mJOA score improved from preoperative 4.3 \u00b1 2.2 to 9.0 \u00b1 2.4 at the last follow-up, and the mean RR was 74.9 \u00b1 26.3%. Disease duration, preoperative nonambulatory status, and the number of decompressed levels were identified as potential risk factors by Univariate analysis (all P &lt; .05). Multivariate analysis showed that the preoperative disease duration and nonambulatory status were independent risk factors for unfavorable outcomes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Long disease duration and nonambulatory status before surgery were independent risk factors for unfavorable outcomes.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/21925682231174194","type":"journal-article","created":{"date-parts":[[2023,5,6]],"date-time":"2023-05-06T07:06:23Z","timestamp":1683356783000},"page":"2288-2297","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":6,"title":["Factors Affecting the Surgical Outcomes of Patients Treated With \u201cde-tension\u201d Surgical Strategy for Multilevel Ossification of the Posterior Longitudinal Ligament in the Thoracic Spine: A Minimum 2-year Follow-Up Study of 83 Patients in a Single Center"],"prefix":"10.1177","volume":"14","author":[{"given":"Guanghui","family":"Chen","sequence":"first","affiliation":[{"name":"Department of Orthopaedics, Peking University Third Hospital, Beijing, China"},{"name":"Beijing Key Laboratory of Spinal Disease Research, Beijing, China"},{"name":"Engineering Research Center of Bone and Joint Precision Medicine, Ministry of Education, Beijing, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tianqi","family":"Fan","sequence":"additional","affiliation":[{"name":"Department of Orthopaedics, Peking University Third Hospital, Beijing, China"},{"name":"Beijing Key Laboratory of Spinal Disease Research, Beijing, China"},{"name":"Engineering Research Center of Bone and Joint Precision Medicine, Ministry of Education, Beijing, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhongqiang","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Orthopaedics, Peking University Third Hospital, Beijing, China"},{"name":"Beijing Key Laboratory of Spinal Disease Research, Beijing, China"},{"name":"Engineering Research Center of Bone and Joint Precision Medicine, Ministry of Education, Beijing, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9512-5436","authenticated-orcid":false,"given":"Weishi","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Orthopaedics, Peking University Third Hospital, Beijing, China"},{"name":"Beijing Key Laboratory of Spinal Disease Research, Beijing, China"},{"name":"Engineering Research Center of Bone and Joint Precision Medicine, Ministry of Education, Beijing, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qiang","family":"Qi","sequence":"additional","affiliation":[{"name":"Department of Orthopaedics, Peking University Third Hospital, Beijing, China"},{"name":"Beijing Key Laboratory of Spinal Disease Research, Beijing, China"},{"name":"Engineering Research Center of Bone and Joint Precision Medicine, Ministry of Education, Beijing, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhaoqing","family":"Guo","sequence":"additional","affiliation":[{"name":"Department of Orthopaedics, Peking University Third Hospital, Beijing, China"},{"name":"Beijing Key Laboratory of Spinal Disease Research, Beijing, China"},{"name":"Engineering Research Center of Bone and Joint Precision Medicine, Ministry of Education, Beijing, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Woquan","family":"Zhong","sequence":"additional","affiliation":[{"name":"Department of Orthopaedics, Peking University Third Hospital, Beijing, China"},{"name":"Beijing Key Laboratory of Spinal Disease Research, Beijing, China"},{"name":"Engineering Research Center of Bone and Joint Precision Medicine, Ministry of Education, Beijing, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yu","family":"Jiang","sequence":"additional","affiliation":[{"name":"Department of Orthopaedics, Peking University Third Hospital, Beijing, China"},{"name":"Beijing Key Laboratory of Spinal Disease Research, Beijing, China"},{"name":"Engineering Research Center of Bone and Joint Precision Medicine, Ministry of Education, Beijing, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chunli","family":"Song","sequence":"additional","affiliation":[{"name":"Department of Orthopaedics, Peking University Third Hospital, Beijing, China"},{"name":"Beijing Key Laboratory of Spinal Disease Research, Beijing, China"},{"name":"Engineering Research Center of Bone and Joint Precision Medicine, Ministry of Education, Beijing, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3478-8361","authenticated-orcid":false,"given":"Chuiguo","family":"Sun","sequence":"additional","affiliation":[{"name":"Department of Orthopaedics, Peking University Third Hospital, Beijing, China"},{"name":"Beijing Key Laboratory of Spinal Disease Research, Beijing, China"},{"name":"Engineering Research Center of Bone and Joint Precision Medicine, Ministry of Education, Beijing, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2023,5,6]]},"reference":[{"key":"bibr1-21925682231174194","doi-asserted-by":"publisher","DOI":"10.1097\/BRS.0000000000002703"},{"key":"bibr2-21925682231174194","doi-asserted-by":"publisher","DOI":"10.1016\/j.spinee.2015.08.060"},{"key":"bibr3-21925682231174194","doi-asserted-by":"publisher","DOI":"10.1097\/01.bsd.0000155033.63557.9c"},{"key":"bibr4-21925682231174194","doi-asserted-by":"publisher","DOI":"10.1097\/01.brs.0000220834.22131.fb"},{"key":"bibr5-21925682231174194","doi-asserted-by":"publisher","DOI":"10.3171\/2010.3.SPINE09237"},{"key":"bibr6-21925682231174194","doi-asserted-by":"publisher","DOI":"10.1097\/BSD.0000000000000188"},{"key":"bibr7-21925682231174194","doi-asserted-by":"publisher","DOI":"10.1007\/s00586-009-0956-2"},{"key":"bibr8-21925682231174194","doi-asserted-by":"publisher","DOI":"10.1038\/sj.sc.3100487"},{"key":"bibr9-21925682231174194","doi-asserted-by":"publisher","DOI":"10.1097\/00007632-199702010-00015"},{"key":"bibr10-21925682231174194","doi-asserted-by":"publisher","DOI":"10.1097\/BSD.0b013e318060091a"},{"key":"bibr11-21925682231174194","doi-asserted-by":"publisher","DOI":"10.1097\/00007632-199011010-00006"},{"key":"bibr12-21925682231174194","doi-asserted-by":"publisher","DOI":"10.1097\/BRS.0b013e31815e3911"},{"key":"bibr13-21925682231174194","doi-asserted-by":"publisher","DOI":"10.1093\/neuros\/nyw130"},{"key":"bibr14-21925682231174194","doi-asserted-by":"publisher","DOI":"10.1016\/j.wneu.2018.10.142"},{"key":"bibr15-21925682231174194","doi-asserted-by":"publisher","DOI":"10.1097\/BRS.0b013e3181714515"},{"key":"bibr16-21925682231174194","doi-asserted-by":"publisher","DOI":"10.1007\/s00586-015-4097-5"},{"key":"bibr17-21925682231174194","doi-asserted-by":"publisher","DOI":"10.1016\/j.spinee.2022.03.007"},{"key":"bibr18-21925682231174194","doi-asserted-by":"publisher","DOI":"10.1097\/01.bsd.0000155033.63557.9c"},{"key":"bibr19-21925682231174194","doi-asserted-by":"publisher","DOI":"10.1097\/BRS.0b013e31816c913b"},{"key":"bibr20-21925682231174194","doi-asserted-by":"publisher","DOI":"10.1097\/BRS.0000000000001622"},{"key":"bibr21-21925682231174194","first-page":"1","author":"Saiwai 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