{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,11]],"date-time":"2026-07-11T13:30:57Z","timestamp":1783776657864,"version":"3.55.0"},"reference-count":33,"publisher":"SAGE Publications","issue":"2","license":[{"start":{"date-parts":[[2023,8,7]],"date-time":"2023-08-07T00:00:00Z","timestamp":1691366400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2023,8,7]],"date-time":"2023-08-07T00:00:00Z","timestamp":1691366400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Global Spine Journal"],"published-print":{"date-parts":[[2025,3]]},"abstract":"<jats:sec>\n                    <jats:title>Study Design<\/jats:title>\n                    <jats:p>Multicenter prospective cohort study.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>Anxiety in combination with osteoporotic vertebral compression fractures (OVCFs) of the spine remains understudied. The purpose of this study was to analyze whether anxiety has an impact on the short-term functional outcome of patients with an OVCF. Furthermore, a direct impact of the fracture on the patient\u2019s anxiety during hospitalization should be recognized.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>All inpatients with an OVCF of the thoracolumbar spine from 2017 to 2020 were included. Trauma mechanism, analgetic medication, anti-osteoporotic therapy, timed-up-and-go test (TuG), mobility, Barthel index, Oswestry-Disability Index (ODI) and EQ5D-5L were documented.<\/jats:p>\n                    <jats:p>For statistical analysis, the U test, chi-square independence test, Spearman correlation, General Linear Model for repeated measures, Bonferroni analysis and Wilcoxon test were used. The item anxiety\/depression of the EQ5D-5L was analyzed to describe the patients\u2019 anxiousness.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Data from 518 patients from 17 different hospitals were evaluated. Fracture severity showed a significant correlation (r = .087,\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = .0496) with anxiety. During the hospital stay, pain medication (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; .001), anti-osteoporotic medication (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; .001), and initiation of surgical therapy (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; .001) were associated with less anxiety. The anxiety of a patient at discharge was negatively related to the functional outcomes at the individual follow-up: TuG (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; .001), Barthel index (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; .001), ODI (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; .001) and EQ5D-5L (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; .001).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Higher anxiety is associated with lower functional outcome after OVCF. The item anxiety\/depression of the EQ5D-5L provides an easily accessible, quick and simple tool that can be used to screen for poor outcomes and may also offer the opportunity for a specific anxiety intervention.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/21925682231192847","type":"journal-article","created":{"date-parts":[[2023,8,7]],"date-time":"2023-08-07T18:03:12Z","timestamp":1691431392000},"page":"417-424","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":6,"title":["Impact of Anxiety During Hospitalization on the Clinical Outcome of Patients With Osteoporotic Thoracolumbar Vertebral Fracture"],"prefix":"10.1177","volume":"15","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0821-193X","authenticated-orcid":false,"given":"F.","family":"Schwarz","sequence":"first","affiliation":[{"name":"University Hospital Jena"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E.","family":"Klee","sequence":"additional","affiliation":[{"name":"University Hospital Jena"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P.","family":"Schenk","sequence":"additional","affiliation":[{"name":"BG Clinic Bergmannstrost Halle (Saale)"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.","family":"Katscher","sequence":"additional","affiliation":[{"name":"Sana Clinic Borna"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"K. 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