{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,2]],"date-time":"2026-07-02T13:09:45Z","timestamp":1782997785961,"version":"3.54.5"},"reference-count":43,"publisher":"SAGE Publications","issue":"2","license":[{"start":{"date-parts":[[2023,10,12]],"date-time":"2023-10-12T00:00:00Z","timestamp":1697068800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2023,10,12]],"date-time":"2023-10-12T00:00:00Z","timestamp":1697068800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"name":"Nature Science Foundation of Hubei Province","award":["2022CFB878"],"award-info":[{"award-number":["2022CFB878"]}]},{"name":"General Hospital of Central Theatre Command of PLA Postdoctoral Foundation","award":["20220224KY29"],"award-info":[{"award-number":["20220224KY29"]}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Global Spine Journal"],"published-print":{"date-parts":[[2025,3]]},"abstract":"<jats:sec>\n                    <jats:title>Study Design<\/jats:title>\n                    <jats:p>Prospective cohort study.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>Diabetes mellitus (DM) is associated with unfavourable patient-reported outcomes after spine surgery. Chronic low back pain (CLBP) with Modic Changes (MCs) in the lumbar vertebrae, as observed on MRI, forms a specific subgroup. This study aims to investigate the potential influence of DM on CLBP with MCs.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This study involved 259 patients with CLBP accompanied MCs. We recorded the patient-reported outcomes (visual analogue scale (VAS), Oswestry Disability Index (ODI), and Roland-Morris Disability Questionnaire (RMDQ)) at baseline, 3, 6, and 12\u00a0months. Multivariable linear regression analyses were performed to determine predictors of patient-reported outcomes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      103 patients had DM. Patients with DM exhibited higher VAS (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; .05), ODI (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; .001), and RMDQ (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; .001) scores at 3, 6, and 12\u00a0months, while patients without DM experienced more significant improvements in the scores over time (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; .001). Patients with DM reported longer durations of physical exercise (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = .007). Additionally, patients without DM had a significantly higher patient satisfaction index (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; .001) and a lower prevalence of hypertension (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; .001). Notably, significant differences were observed in the distribution of MCs of lumbar vertebrae (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = .034) and Pfirrmann grades of intervertebral disc degeneration between two groups (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; .001).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Patients with DM demonstrated poorer patient-reported outcomes compared to those without DM in 1-year. DM emerged as an independent predictor of adverse patient-reported outcomes. It can be utilized to enhance the management and treatment of CLBP in patients with MCs.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/21925682231206962","type":"journal-article","created":{"date-parts":[[2023,10,12]],"date-time":"2023-10-12T11:46:42Z","timestamp":1697111202000},"page":"722-730","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":8,"title":["The Impact of Diabetes Mellitus on Patient-Reported Outcomes of Chronic Low Back Pain with Modic Changes at One Year: A Prospective Cohort Study"],"prefix":"10.1177","volume":"15","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1969-6226","authenticated-orcid":false,"given":"Yongkang","family":"Chen","sequence":"first","affiliation":[{"name":"General Hospital of Central Theatre Command of PLA"},{"name":"Southern Medical 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