{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,12]],"date-time":"2026-08-12T14:00:45Z","timestamp":1786543245542,"version":"build-2736575974"},"reference-count":29,"publisher":"SAGE Publications","issue":"2","license":[{"start":{"date-parts":[[2023,10,25]],"date-time":"2023-10-25T00:00:00Z","timestamp":1698192000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2023,10,25]],"date-time":"2023-10-25T00:00:00Z","timestamp":1698192000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Global Spine Journal"],"published-print":{"date-parts":[[2025,3]]},"abstract":"<jats:sec>\n                    <jats:title>Study Design<\/jats:title>\n                    <jats:p>Retrospective cohort study.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>Physicians may be deterred from operating on elderly patients due to fears of poorer outcomes and complications. We aimed to compare the outcomes of surgical treatment of spinal metastases patients aged \u226570-yrs and &lt;70-yrs<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods<\/jats:title>\n                    <jats:p>\n                      This is a retrospective study of patients surgically treated for metastatic epidural spinal cord compression and spinal instability between January-2005 to December-2021. Follow-up was till death or minimum 1-year post-surgery. Outcomes included post-operative neurological status, ambulatory status, medical and surgical complications. Two Sample\n                      <jats:italic toggle=\"yes\">t<\/jats:italic>\n                      -test\/Mann Whitney U test were used for numerical variables and Pearson Chi-Squared or Fishers Exact test for categorical variables. Survival was presented with a Kaplan-Meier curve.\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; .05 was significant.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      We identified 412 patients of which 29 (7.1%) patients were excluded due to loss to follow-up and previous surgical treatment. 79 (20.6%) were \u226570-yrs. Age \u226570-yrs patients had poorer ECOG scores (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = .0017) and Charlson Comorbidity Index (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; .001). No significant difference in modified Tokuhashi score (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = .393) was observed with significantly more \u2265 prostate (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; .001) and liver (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = .029) cancer in \u226570-yrs. Improved or maintained normal neurological function (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = .934), independent ambulatory status (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = .171), and survival at 6 months (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = .119) and 12\u00a0months (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = .659) was not significantly different between both groups. Medical (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = .528) or surgical (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = .466) complication rates and readmission rates (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = .800) were similar.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>\u226570-yrs patients have comparable outcomes to &lt;70-yr old patients with no significant increase in complication rates. Age should not be a determining factor in deciding surgical management of spinal metastases.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/21925682231209624","type":"journal-article","created":{"date-parts":[[2023,10,26]],"date-time":"2023-10-26T02:41:01Z","timestamp":1698288061000},"page":"731-741","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":7,"title":["Outcomes and Complications of Surgery for Symptomatic Spinal Metastases; a Comparison Between Patients Aged \u2265 70 and &lt;70"],"prefix":"10.1177","volume":"15","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9237-2586","authenticated-orcid":false,"given":"Jiong Hao Jonathan","family":"Tan","sequence":"first","affiliation":[{"name":"National University Health System"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James Thomas Patrick Decourcy","family":"Hallinan","sequence":"additional","affiliation":[{"name":"National University Hospital"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7205-118X","authenticated-orcid":false,"given":"Shi Wei","family":"Ang","sequence":"additional","affiliation":[{"name":"NUHS"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tuan Hao","family":"Tan","sequence":"additional","affiliation":[{"name":"NUHS"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hwee Inn Joelle","family":"Tan","sequence":"additional","affiliation":[{"name":"NUHS"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Le Tian Isaac","family":"Tan","sequence":"additional","affiliation":[{"name":"NUHS"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qinxiang Shant","family":"Sin","sequence":"additional","affiliation":[{"name":"NUHS"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Renick","family":"Lee","sequence":"additional","affiliation":[{"name":"National University Health 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