{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,24]],"date-time":"2026-10-24T00:01:40Z","timestamp":1792800100964,"version":"4.5.0"},"reference-count":23,"publisher":"SAGE Publications","issue":"1_suppl","license":[{"start":{"date-parts":[[2024,2,1]],"date-time":"2024-02-01T00:00:00Z","timestamp":1706745600000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"name":"AO Spine Knowledge Forum Trauma","id":[{"id":"https:\/\/ror.org\/02z64pq54","id-type":"ROR","asserted-by":"crossref"}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Global Spine Journal"],"published-print":{"date-parts":[[2024,2]]},"abstract":"<jats:sec>\n                    <jats:title>Study Design<\/jats:title>\n                    <jats:p>This paper presents a description of a conceptual framework and methodology that is applicable to the manuscripts that comprise this focus issue.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>Our goal is to present a conceptual framework which is relied upon to better understand the processes through which surgeons make therapeutic decisions around how to treat thoracolumbar burst fractures (TL) fractures.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We will describe the methodology used in the AO Spine TL A3\/4 Study prospective observational study and how the radiographs collected for this study were utilized to study the relationships between various variables that factor into surgeon decision making.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>With 22 expert spine trauma surgeons analyzing the acute CT scans of 183 patients with TL fractures we were able to perform pairwise analyses, look at reliability and correlations between responses and develop frequency tables, and regression models to assess the relationships and interactions between variables. We also used machine learning to develop decision trees.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>This paper outlines the overall methodological elements that are common to the subsequent papers in this focus issue.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/21925682231210183","type":"journal-article","created":{"date-parts":[[2024,2,7]],"date-time":"2024-02-07T13:31:50Z","timestamp":1707312710000},"page":"8S-16S","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":14,"title":["Understanding Decision Making as It Influences Treatment in Thoracolumbar Burst Fractures Without Neurological Deficit: Conceptual Framework and Methodology"],"prefix":"10.1177","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4520-6454","authenticated-orcid":false,"given":"Charlotte","family":"Dandurand","sequence":"first","affiliation":[{"name":"Combined Neurosurgical and Orthopedic Spine Program, Vancouver General Hospital, University of British Columbia, Vancouver, BC, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cumhur F.","family":"\u00d6ner","sequence":"additional","affiliation":[{"name":"University Medical Centers, Utrecht, Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Olesja","family":"Hazenbiller","sequence":"additional","affiliation":[{"name":"AO Spine, AO Network Clinical Research, AO Foundation, Davos, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Richard J.","family":"Bransford","sequence":"additional","affiliation":[{"name":"Harborview Medical Center, Department of Orthopaedics and Sports Medicine, University of Washington, Seattle, WA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Klaus","family":"Schnake","sequence":"additional","affiliation":[{"name":"Center for Spinal and Scoliosis Surgery, Malteser Waldkrankenhaus St. Marien, Erlangen, Germany"},{"name":"Private Medical University Nuremberg, Nuremberg, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexander R.","family":"Vaccaro","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery, Rothman Institute, Thomas Jefferson University Hospital, Philadelphia, PA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5320-5638","authenticated-orcid":false,"given":"Lorin M.","family":"Benneker","sequence":"additional","affiliation":[{"name":"Spine Unit, Sonnenhof Spital, University of Bern, Bern, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1157-4889","authenticated-orcid":false,"given":"Emiliano","family":"Vialle","sequence":"additional","affiliation":[{"name":"Cajuru Hospital, Catholic University of Paran\u00e1, Curitiba, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gregory D.","family":"Schroeder","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery, Rothman Institute, Thomas Jefferson University Hospital, Philadelphia, PA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6043-006X","authenticated-orcid":false,"given":"Shanmuganathan","family":"Rajasekaran","sequence":"additional","affiliation":[{"name":"Department of Orthopaedics and Spine Surgery, Ganga Hospital, Coimbatore, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6177-7145","authenticated-orcid":false,"given":"Mohammad","family":"El-Skarkawi","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic and Trauma Surgery, Faculty of Medicine, Assiut University, Assiut, Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5817-4909","authenticated-orcid":false,"given":"Rishi M.","family":"Kanna","sequence":"additional","affiliation":[{"name":"Department of Orthopaedics and Spine Surgery, Ganga Hospital, Coimbatore, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5221-8288","authenticated-orcid":false,"given":"Mohamed","family":"Aly","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Prince Mohammed Bin Abdulaziz Hospital, Riyadh, Saudi Arabia"},{"name":"Department of Neurosurgery, Mansoura University, Mansoura, Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3763-8767","authenticated-orcid":false,"given":"Martin","family":"Holas","sequence":"additional","affiliation":[{"name":"Klinika \u00darazovej Chirurgie SZU a FNsP F.D.Roosevelta, Bansk\u00e1 Bystrica, Slovakia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2152-5725","authenticated-orcid":false,"given":"Jose A.","family":"Canseco","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery, Rothman Institute, Thomas Jefferson University Hospital, Philadelphia, PA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sander","family":"Muijs","sequence":"additional","affiliation":[{"name":"University Medical Centers, Utrecht, Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5732-5402","authenticated-orcid":false,"given":"Eugen Cezar","family":"Popescu","sequence":"additional","affiliation":[{"name":"Prof. Dr. N. Oblu\u201d Emergency Hospital, Iasi, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jin Wee","family":"Tee","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, National Trauma Research Institute (NTRI), The Alfred Hospital, Melbourne, VIC, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5684-7679","authenticated-orcid":false,"given":"Gaston","family":"Camino-Willhuber","sequence":"additional","affiliation":[{"name":"Orthopaedic and Traumatology Department, Institute of Orthopedics \u201cCarlos E. Ottolenghi\u201d Hospital Italiano de Buenos Aires, Buenes Aires, Argentina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2645-0483","authenticated-orcid":false,"given":"Andrei Fernandes","family":"Joaquim","sequence":"additional","affiliation":[{"name":"Neurosurgery Division, Department of Neurology, State University of Campinas, Sao Paulo, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ory","family":"Keynan","sequence":"additional","affiliation":[{"name":"Rambam Health Care Campus, Haifa, Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Harvinder Singh","family":"Chhabra","sequence":"additional","affiliation":[{"name":"Sri Balaji Action Medical Institute, New Delhi, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4649-0610","authenticated-orcid":false,"given":"Sebastian","family":"Bigdon","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery and Traumatology, Inselspital, University Hospital, University of Bern, Bern, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5179-4192","authenticated-orcid":false,"given":"Ulrich","family":"Spiegel","sequence":"additional","affiliation":[{"name":"Department of Orthopaedics, Trauma Surgery and Plastic Surgery, University of Leipzig, Leipzig, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marcel F.","family":"Dvorak","sequence":"additional","affiliation":[{"name":"Combined Neurosurgical and Orthopedic Spine Program, Vancouver General Hospital, University of British Columbia, Vancouver, BC, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2024,2,7]]},"reference":[{"key":"bibr1-21925682231210183","doi-asserted-by":"publisher","DOI":"10.1177\/2192568217699202"},{"issue":"3","key":"bibr2-21925682231210183","first-page":"279","volume":"68","author":"Aligizakis A","year":"2002","journal-title":"Acta Orthop Belg"},{"key":"bibr3-21925682231210183","doi-asserted-by":"publisher","DOI":"10.1097\/00007632-200105010-00010"},{"key":"bibr4-21925682231210183","doi-asserted-by":"publisher","DOI":"10.1007\/s001130050537"},{"key":"bibr5-21925682231210183","doi-asserted-by":"publisher","DOI":"10.1016\/j.surneu.2006.08.081"},{"key":"bibr6-21925682231210183","doi-asserted-by":"publisher","DOI":"10.1007\/s11999-011-2157-7"},{"issue":"2","key":"bibr7-21925682231210183","first-page":"115","volume":"57","author":"Ghobrial GM","year":"2013","journal-title":"J Neurosurg Sci"},{"key":"bibr8-21925682231210183","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD005079.pub3"},{"key":"bibr9-21925682231210183","doi-asserted-by":"publisher","DOI":"10.3171\/2014.4.FOCUS1467"},{"key":"bibr10-21925682231210183","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM198707163170304"},{"key":"bibr11-21925682231210183","doi-asserted-by":"publisher","DOI":"10.1097\/BRS.0b013e3182a8a381"},{"key":"bibr12-21925682231210183","unstructured":"AOTranslation Center Innovation. Thoracolumbar burst fractures (AOSpine A3, A4) in neurologically intact patients: an observational, multicenter cohort study comparing surgical versus non-surgical treatment. 2021. clinicaltrials.gov. https:\/\/clinicaltrials.gov\/ct2\/show\/NCT02827214 Accessed January 20, 2022."},{"key":"bibr13-21925682231210183","doi-asserted-by":"publisher","DOI":"10.1097\/01.brs.0000218072.25964.a9"},{"issue":"3","key":"bibr14-21925682231210183","first-page":"209","volume":"18","author":"Vaccaro AR","year":"2005","journal-title":"J Spinal Disord Tech"},{"key":"bibr15-21925682231210183","doi-asserted-by":"publisher","DOI":"10.1007\/s10742-018-0192-5"},{"key":"bibr16-21925682231210183","doi-asserted-by":"publisher","DOI":"10.1007\/s002689900649"},{"key":"bibr17-21925682231210183","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM200006223422507"},{"key":"bibr18-21925682231210183","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9343(90)90182-d"},{"key":"bibr19-21925682231210183","doi-asserted-by":"publisher","DOI":"10.1016\/j.spinee.2007.11.008"},{"key":"bibr20-21925682231210183","doi-asserted-by":"publisher","DOI":"10.1097\/BRS.0b013e31816c8b32"},{"key":"bibr21-21925682231210183","doi-asserted-by":"publisher","DOI":"10.1097\/BOT.0b013e3181a18728"},{"key":"bibr22-21925682231210183","doi-asserted-by":"publisher","DOI":"10.1007\/s00586-016-4911-8"},{"key":"bibr23-21925682231210183","doi-asserted-by":"publisher","DOI":"10.1007\/s00586-010-1451-5"}],"container-title":["Global Spine Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/21925682231210183","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/21925682231210183","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/21925682231210183","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T07:16:10Z","timestamp":1777446970000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/21925682231210183"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,2]]},"references-count":23,"journal-issue":{"issue":"1_suppl","published-print":{"date-parts":[[2024,2]]}},"alternative-id":["10.1177\/21925682231210183"],"URL":"https:\/\/doi.org\/10.1177\/21925682231210183","relation":{},"ISSN":["2192-5682","2192-5690"],"issn-type":[{"value":"2192-5682","type":"print"},{"value":"2192-5690","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,2]]}}}