{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,12]],"date-time":"2026-10-12T01:13:12Z","timestamp":1791767592761,"version":"4.3.4"},"reference-count":26,"publisher":"SAGE Publications","issue":"2","license":[{"start":{"date-parts":[[2024,6,18]],"date-time":"2024-06-18T00:00:00Z","timestamp":1718668800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2024,6,18]],"date-time":"2024-06-18T00:00:00Z","timestamp":1718668800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Global Spine Journal"],"published-print":{"date-parts":[[2025,3]]},"abstract":"<jats:sec>\n                    <jats:title>Study Design<\/jats:title>\n                    <jats:p>Systematic review and meta-analysis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>Surgical management of osteoporotic vertebral compression fractures (OVCFs) has traditionally consisted of vertebroplasty or kyphoplasty procedures. Mechanical percutaneous vertebral body augmentation (MPVA) systems have recently been introduced as alternatives to traditional methods. However, the effectiveness of MPVA systems vs conventional augmentation techniques for OVCFs remains unclear. This serves as the premise for this study.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      A systematic review and meta-analysis was conducted as per the\n                      <jats:italic toggle=\"yes\">Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA)<\/jats:italic>\n                      guidelines. Studies of interest included randomized controlled trials (RCTs) which directly compared patient outcomes following kyphoplasty to patients treated with MPVA systems. Clinical and radiological findings were collated and compared for significance between cohorts.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      6 RCTs were identified with 1024 patients total. The mean age of all patients was 73.5\u00a0years. 17% of the cohort were male, 83% were female. 515 patients underwent kyphoplasty and 509 underwent mechanical vertebral body augmentation using MPVA systems. MPVAs showed similar efficacy for restoration of vertebral body height (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = .18), total complications (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = .36), cement extravasation (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = .58) and device-related complications (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = .06). MPVAs also showed reduced rates of all new fractures (16.4% vs 22.2%;\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = .17) and adjacent fractures (14.7% vs 18.9%;\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = .23), with improved visual analogue scale (VAS) scores at 6-month (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = .13).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>The results of this meta-analysis highlight no significant improvement in clinical or radiological outcomes for MPVA systems when compared to balloon kyphoplasty for vertebral body augmentation. Further research is needed to establish a true benefit over traditional operative methods.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/21925682241261988","type":"journal-article","created":{"date-parts":[[2024,6,18]],"date-time":"2024-06-18T17:11:51Z","timestamp":1718730711000},"page":"1356-1366","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":9,"title":["Mechanical Vertebral Body Augmentation Versus Conventional Balloon Kyphoplasty for Osteoporotic Thoracolumbar Compression Fractures: A Systematic Review and Meta-Analysis of Outcomes"],"prefix":"10.1177","volume":"15","author":[{"given":"Matthew","family":"Macciacchera","sequence":"first","affiliation":[{"name":"Royal College of Surgeons in Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8002-8024","authenticated-orcid":false,"given":"Jake M.","family":"McDonnell","sequence":"additional","affiliation":[{"name":"Mater Misericordiae University Hospital"},{"name":"Trinity College Dublin"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aisyah","family":"Amir","sequence":"additional","affiliation":[{"name":"Royal College of Surgeons in Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0003-0216-1975","authenticated-orcid":false,"given":"Aubrie","family":"Sowa","sequence":"additional","affiliation":[{"name":"Mater Misericordiae University Hospital"},{"name":"University of College Dublin"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7085-1706","authenticated-orcid":false,"given":"Gr\u00e1inne","family":"Cunniffe","sequence":"additional","affiliation":[{"name":"Mater Misericordiae University Hospital"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stacey","family":"Darwish","sequence":"additional","affiliation":[{"name":"Mater Misericordiae University Hospital"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ciara","family":"Murphy","sequence":"additional","affiliation":[{"name":"Trinity College Dublin"},{"name":"Royal College of Surgeons in Ireland"},{"name":"Trinity College Dublin"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joseph S.","family":"Butler","sequence":"additional","affiliation":[{"name":"Mater Misericordiae University Hospital"},{"name":"University of College Dublin"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2024,6,18]]},"reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1186\/s13018-021-02772-0"},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00198-016-3494-x"},{"key":"e_1_3_3_4_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00198-006-0172-4"},{"key":"e_1_3_3_5_2","doi-asserted-by":"publisher","DOI":"10.1097\/BRS.0b013e31826b3aef"},{"key":"e_1_3_3_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.spinee.2013.06.094"},{"key":"e_1_3_3_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.spinee.2019.07.009"},{"key":"e_1_3_3_8_2","doi-asserted-by":"publisher","DOI":"10.3389\/fmed.2023.1161174"},{"key":"e_1_3_3_9_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pmed.1000100"},{"key":"e_1_3_3_10_2","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.l4898"},{"key":"e_1_3_3_11_2","doi-asserted-by":"publisher","DOI":"10.1097\/BRS.0000000000000906"},{"key":"e_1_3_3_12_2","doi-asserted-by":"publisher","DOI":"10.2106\/JBJS.L.00024"},{"key":"e_1_3_3_13_2","doi-asserted-by":"publisher","DOI":"10.4103\/0974-8237.116537"},{"key":"e_1_3_3_14_2","doi-asserted-by":"publisher","DOI":"10.1155\/2020\/3947368"},{"key":"e_1_3_3_15_2","doi-asserted-by":"publisher","DOI":"10.1002\/jbmr.3653"},{"key":"e_1_3_3_16_2","doi-asserted-by":"publisher","DOI":"10.3171\/2019.8.SPINE19479"},{"key":"e_1_3_3_17_2","doi-asserted-by":"publisher","DOI":"10.1089\/sur.2017.089"},{"issue":"4","key":"e_1_3_3_18_2","first-page":"429","article-title":"The present role of vertebroplasty and kyphoplasty in the treatment of fresh vertebral compression fractures","volume":"65","author":"R\u00f6llinghoff M","year":"2010","unstructured":"R\u00f6llinghoff M, Zarghooni K, Dargel J, et al. The present role of vertebroplasty and kyphoplasty in the treatment of fresh vertebral compression fractures. Minerva Chir. 2010;65(4):429-437.","journal-title":"Minerva Chir"},{"key":"e_1_3_3_19_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.wneu.2018.10.143"},{"issue":"5","key":"e_1_3_3_20_2","first-page":"E725","article-title":"Predictive factors for adjacent vertebral fractures after percutaneous kyphoplasty in patients with osteoporotic vertebral compression fracture","volume":"25","author":"Tao W","year":"2022","unstructured":"Tao W, Biao W, Xingmei C, et al. Predictive factors for adjacent vertebral fractures after percutaneous kyphoplasty in patients with osteoporotic vertebral compression fracture. Pain Physician. 2022;25(5):E725-E732.","journal-title":"Pain Physician"},{"key":"e_1_3_3_21_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0065119"},{"issue":"4","key":"e_1_3_3_22_2","first-page":"380","article-title":"Osseofix\u00ae system for percutaneous stabilization of osteoporotic and tumorous vertebral compression fractures - clinical and radiological results after 12 months","volume":"186","author":"Ender SA","year":"2014","unstructured":"Ender SA, Gradl G, Ender M, Langner S, Merk HR, Kayser R. Osseofix\u00ae system for percutaneous stabilization of osteoporotic and tumorous vertebral compression fractures - clinical and radiological results after 12 months. Rofo. 2014;186(4):380-387.","journal-title":"Rofo"},{"key":"e_1_3_3_23_2","doi-asserted-by":"publisher","DOI":"10.1007\/s40520-019-01289-1"},{"key":"e_1_3_3_24_2","doi-asserted-by":"publisher","DOI":"10.1097\/BRS.0000000000000112"},{"key":"e_1_3_3_25_2","doi-asserted-by":"publisher","DOI":"10.36076\/ppj.2013\/16\/E505"},{"key":"e_1_3_3_26_2","doi-asserted-by":"publisher","DOI":"10.1155\/2014\/853897"},{"key":"e_1_3_3_27_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.arth.2020.06.072"}],"container-title":["Global Spine Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/21925682241261988","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/21925682241261988","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/21925682241261988","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T07:20:48Z","timestamp":1777447248000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/21925682241261988"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,6,18]]},"references-count":26,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2025,3]]}},"alternative-id":["10.1177\/21925682241261988"],"URL":"https:\/\/doi.org\/10.1177\/21925682241261988","relation":{},"ISSN":["2192-5682","2192-5690"],"issn-type":[{"value":"2192-5682","type":"print"},{"value":"2192-5690","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,6,18]]}}}