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Main search terms included \u201cperioperative complications\u201d, \u201cmedical complications\u201d and \u201cadult spinal deformity\u201d. In the various complications associated with deformity surgeries, we focused the medical complications which will directly link to patient\u2019s life prognosis rather than postoperative mechanical complications.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>The overall perioperative complication rate ranged from 12.8% to 52.2%. Risk factors for perioperative medical complications included age, body mass index, osteoporosis, frailty, comorbidities, preoperative medication, smoking habit, and alcohol intake. Perioperative medical complications mostly depend on patient-related factors. Taking reference from the previous reported classification of surgical complications, the AO Spine Deformity Knowledge Forum developed a classification for complications of spinal deformity surgery via a Delphi exercise.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Complication classification system is important for understanding the impact of complications on patients. Further research should aim to determine the correlation between the new complication classification and patient outcomes in spinal deformity surgery. Various pre-, intra-, and postoperative strategies should be implemented to prevent perioperative complications.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/21925682241264227","type":"journal-article","created":{"date-parts":[[2025,7,9]],"date-time":"2025-07-09T15:00:43Z","timestamp":1752073243000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":4,"title":["Perioperative Medical Complications in Adult Spine Deformity Surgery: Classification and Prevention Strategies"],"prefix":"10.1177","volume":"15","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0265-6372","authenticated-orcid":false,"given":"Go","family":"Yoshida","sequence":"first","affiliation":[{"name":"Hamamatsu University School of Medicine"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2765-822X","authenticated-orcid":false,"given":"Kazunori","family":"Hayashi","sequence":"additional","affiliation":[{"name":"Osaka City Juso Hospital"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Louis","family":"Boissiere","sequence":"additional","affiliation":[{"name":"Bordeaux University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Allan","family":"Martin","sequence":"additional","affiliation":[{"name":"University of California Davis"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sigurd","family":"Berven","sequence":"additional","affiliation":[{"name":"University of California San Francisco"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lawrence G.","family":"Lenke","sequence":"additional","affiliation":[{"name":"Columbia University Irving Medical Center"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9173-8443","authenticated-orcid":false,"given":"Stephen J.","family":"Lewis","sequence":"additional","affiliation":[{"name":"The Hospital for Sick Children"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yukihiro","family":"Matsuyama","sequence":"additional","affiliation":[{"name":"Hamamatsu University School of Medicine"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eric","family":"Klineberg","sequence":"additional","affiliation":[{"name":"University of California Davis"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"AO Spine Knowledge Forum Deformity","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2025,7,9]]},"reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1097\/BRS.0b013e3181b3ff0c"},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.1097\/BRS.0b013e3181e21783"},{"key":"e_1_3_3_4_2","doi-asserted-by":"publisher","DOI":"10.1097\/BRS.0b013e3181a8fdc8"},{"key":"e_1_3_3_5_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00586-012-2370-4"},{"key":"e_1_3_3_6_2","doi-asserted-by":"publisher","DOI":"10.1097\/BRS.0b013e31815a7644"},{"key":"e_1_3_3_7_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00586-015-4275-5"},{"key":"e_1_3_3_8_2","doi-asserted-by":"publisher","DOI":"10.1097\/BRS.0b013e3182059bfd"},{"key":"e_1_3_3_9_2","doi-asserted-by":"publisher","DOI":"10.1097\/BRS.0000000000001774"},{"key":"e_1_3_3_10_2","doi-asserted-by":"publisher","DOI":"10.3171\/2015.11.SPINE151036"},{"key":"e_1_3_3_11_2","doi-asserted-by":"publisher","DOI":"10.3171\/2017.10.SPINE17374"},{"key":"e_1_3_3_12_2","doi-asserted-by":"publisher","DOI":"10.1097\/BRS.0000000000001636"},{"key":"e_1_3_3_13_2","doi-asserted-by":"publisher","DOI":"10.3171\/2017.3.SPINE161011"},{"key":"e_1_3_3_14_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jos.2016.11.006"},{"key":"e_1_3_3_15_2","doi-asserted-by":"publisher","DOI":"10.1097\/BRS.0000000000002411"},{"key":"e_1_3_3_16_2","doi-asserted-by":"publisher","DOI":"10.1177\/2192568220937473"},{"key":"e_1_3_3_17_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jocn.2016.12.039"},{"key":"e_1_3_3_18_2","doi-asserted-by":"publisher","DOI":"10.1097\/BRS.0b013e31827ae242"},{"key":"e_1_3_3_19_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jocn.2018.10.104"},{"key":"e_1_3_3_20_2","doi-asserted-by":"publisher","DOI":"10.1097\/BRS.0000000000001202"},{"key":"e_1_3_3_21_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00586-014-3542-1"},{"key":"e_1_3_3_22_2","volume-title":"The RAND\/UCLA Appropriateness Method User\u2019s Manual","author":"Fitch K","year":"2001","unstructured":"Fitch K, Bernstein SJ, Aguilar MD, et al. 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