{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T10:22:55Z","timestamp":1787048575044,"version":"build-2736575974"},"reference-count":27,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[2025,7,3]],"date-time":"2025-07-03T00:00:00Z","timestamp":1751500800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2025,7,3]],"date-time":"2025-07-03T00:00:00Z","timestamp":1751500800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Global Spine Journal"],"published-print":{"date-parts":[[2026,1]]},"abstract":"<jats:sec>\n                    <jats:title>Study design<\/jats:title>\n                    <jats:p>Prospective cohort study.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>Treatment for thoracolumbar (TL) burst fractures in neurologically intact patients remains controversial. The goal of this study was to utilize the international equipoise to determine whether surgery leads to a more rapid improvement of disability measured by minimal clinically important difference (MCID) in Oswestry Disability Index (ODI).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>The primary endpoint was time to achieve an improvement in ODI of more than 12.8 points within 1\u00a0year after baseline (MCID). A post hoc analysis was conducted to assess time to minimal disability (ODI of &lt;20). Time-to-event analyses were applied, including log rank test for equality of survivor functions, Kaplan Meier survival curves and Cox proportional hazard models.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      One hundred and ninety-eight patients were included (122 surgical and 76 non-surgical patients). Median time to achieve MCID in ODI (12.8 points) from baseline was similar between the two groups (25.0\u00a0days vs 25.5\u00a0days,\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.517). Post hoc analysis showed a potential trend towards a short time to achieve minimal disability for the surgical group (69.0\u00a0days vs 82.0\u00a0days,\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.057). Similar results were obtained when excluding all patients with suspected PLC injury.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Surgically and non-surgically treated patients with thoracolumbar burst fractures without neurological injury were similar in terms of time to reaching MCID in ODI at 1\u00a0year. Surgical patients may reach minimal disability faster than nonsurgical patients, but additional large scale studies are warranted.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Level of Evidence<\/jats:title>\n                    <jats:p>Therapeutic Prospective Comparative Cohort Study Level II.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/21925682251356910","type":"journal-article","created":{"date-parts":[[2025,7,3]],"date-time":"2025-07-03T03:09:59Z","timestamp":1751512199000},"page":"628-638","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":10,"title":["Surgical versus Non-Surgical Treatment of Thoracolumbar Burst Fractures in Neurologically Intact Patients: A Prospective International Multicentre Cohort Study"],"prefix":"10.1177","volume":"16","author":[{"given":"Marcel F.","family":"Dvorak","sequence":"first","affiliation":[{"name":"University of British Columbia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cumhur F.","family":"\u00d6ner","sequence":"additional","affiliation":[{"name":"University Medical Center"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4520-6454","authenticated-orcid":false,"given":"Charlotte","family":"Dandurand","sequence":"additional","affiliation":[{"name":"University of British Columbia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Klaus John","family":"Schnake","sequence":"additional","affiliation":[{"name":"Malteser Waldrankenhaus St. Marien Center for Spinal Surgery and Scoliosis"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2293-5774","authenticated-orcid":false,"given":"Richard J.","family":"Bransford","sequence":"additional","affiliation":[{"name":"University of Washington School of Medicine"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5732-5402","authenticated-orcid":false,"given":"Eugen Cezar","family":"Popescu","sequence":"additional","affiliation":[{"name":"Prof. Dr. N. Oblu\u201d Emergency Hospital"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6177-7145","authenticated-orcid":false,"given":"Mohammed","family":"El-Sharkawi","sequence":"additional","affiliation":[{"name":"Assiut University Medical School Assiut"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6043-006X","authenticated-orcid":false,"given":"Shanmuganathan","family":"Rajasekaran","sequence":"additional","affiliation":[{"name":"Ganga Hospital"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5320-5638","authenticated-orcid":false,"given":"Lorin M.","family":"Benneker","sequence":"additional","affiliation":[{"name":"University of Bern"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Greg D.","family":"Schroeder","sequence":"additional","affiliation":[{"name":"Thomas Jefferson University"},{"name":"Thomas Jefferson University Hospital"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jin W.","family":"Tee","sequence":"additional","affiliation":[{"name":"The Alfred Hospital"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John C.","family":"France","sequence":"additional","affiliation":[{"name":"West Virginia University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1390-2428","authenticated-orcid":false,"given":"J\u00e9r\u00f4me","family":"Paquet","sequence":"additional","affiliation":[{"name":"CHU de Quebec, Universit\u00e9 Laval"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Richard","family":"Allen","sequence":"additional","affiliation":[{"name":"University of California"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2525-6080","authenticated-orcid":false,"given":"William F.","family":"Lavelle","sequence":"additional","affiliation":[{"name":"SUNY Upstate Medical University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4053-6753","authenticated-orcid":false,"given":"Miguel","family":"Hirschfeld","sequence":"additional","affiliation":[{"name":"Orthopedic Surgery and Traumatology"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Spyros","family":"Pneumaticos","sequence":"additional","affiliation":[{"name":"KAT Hospital"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1157-4889","authenticated-orcid":false,"given":"Emiliano","family":"Vialle","sequence":"additional","affiliation":[{"name":"Cajuru University Hospital"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexander R.","family":"Vaccaro","sequence":"additional","affiliation":[{"name":"Thomas Jefferson University Hospital"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2025,7,3]]},"reference":[{"key":"e_1_3_4_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.surneu.2006.08.081"},{"issue":"2","key":"e_1_3_4_3_2","first-page":"115","article-title":"Thoracolumbar spine trauma: review of the evidence","volume":"57","author":"Ghobrial GM","year":"2013","unstructured":"Ghobrial GM, Jallo J. 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