{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T18:04:00Z","timestamp":1777658640614,"version":"3.51.4"},"reference-count":53,"publisher":"SAGE Publications","issue":"2","license":[{"start":{"date-parts":[[2025,9,1]],"date-time":"2025-09-01T00:00:00Z","timestamp":1756684800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2025,9,1]],"date-time":"2025-09-01T00:00:00Z","timestamp":1756684800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Global Spine Journal"],"published-print":{"date-parts":[[2026,3]]},"abstract":"<jats:sec>\n                    <jats:title>Study Design<\/jats:title>\n                    <jats:p>Retrospective cohort study.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>To assess the effect of alcohol, nicotine, and opioid use history on 90\u00a0day and 1\u00a0year postoperative complications after elective laminectomy.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Using the TriNetX Database (2004-2025), adult patients undergoing elective laminectomy were divided into cohorts with a history of alcohol, nicotine, or opioid abuse\/dependence, matched 1:1 with controls (age, sex, race, body mass index, comorbidities). Exclusions included malignancy, preceding trauma, and prior complications. Outcomes included the development of acute kidney failure, sepsis, emergency department visits, deep vein thrombosis, myocardial infarction, pulmonary embolism, pneumonia, stroke, and mortality at 90\u00a0days and 1\u00a0year.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Matched cohorts comprised 4053 alcohol, 22\u00a0469 nicotine, and 2724 opioid patients, each with controls. Alcohol abuse was significantly associated with increased odds of death, DVT, MI, pneumonia, sepsis, and stroke following elective laminectomy at 90 days, and with acute renal failure, PE, pneumonia, stroke, sepsis, DVT, and death at 1\u00a0year (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; 0.05). Nicotine dependence significantly elevated the risk of death, MI, pneumonia, and sepsis at 90\u00a0days, and at 1\u00a0year, remained associated with increased odds of acute renal failure, stroke, ED visits, MI, pneumonia, sepsis, and death (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; 0.05). Opioid abuse was significantly linked to higher risks of DVT, MI, pneumonia, sepsis, stroke, and death at 90 days, with persistent 1-year risks for acute renal failure, MI, pneumonia, sepsis, and death (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; 0.05).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Alcohol, nicotine, and opioid use significantly heighten postoperative complications after laminectomy, underscoring the need for preoperative risk evaluation and tailored interventions.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/21925682251371593","type":"journal-article","created":{"date-parts":[[2025,9,1]],"date-time":"2025-09-01T15:26:36Z","timestamp":1756740396000},"page":"1085-1094","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":1,"title":["The Impact of Alcohol, Nicotine, and Opioid Use History on 90-Day and 1-Year Postoperative Complications Following Elective Laminectomy: A Nationwide Propensity-Matched Study"],"prefix":"10.1177","volume":"16","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5738-9526","authenticated-orcid":false,"given":"Zuhair","family":"Zaidi","sequence":"first","affiliation":[{"name":"UT Southwestern Medical School"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0003-9806-3869","authenticated-orcid":false,"given":"Asim","family":"Mohamed","sequence":"additional","affiliation":[{"name":"UT Southwestern Medical School"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Billal","family":"Homayoun","sequence":"additional","affiliation":[{"name":"UT Southwestern Medical School"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Muaz","family":"Wahid","sequence":"additional","affiliation":[{"name":"UT Southwestern Medical School"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3499-7569","authenticated-orcid":false,"given":"Salah","family":"Aoun","sequence":"additional","affiliation":[{"name":"UT Southwestern Medical Center"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael","family":"Van Hal","sequence":"additional","affiliation":[{"name":"UT Southwestern Medical Center"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2025,9,1]]},"reference":[{"key":"e_1_3_6_2_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2010.338"},{"key":"e_1_3_6_3_2","volume-title":"Key Substance Use and Mental Health Indicators in the United States: Results from the 2021 National Survey on Drug Use and Health","year":"2022","unstructured":"Key Substance Use and Mental Health Indicators in the United States: Results from the 2021 National Survey on Drug Use and Health. 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