{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T05:02:45Z","timestamp":1791349365739,"version":"4.3.1"},"reference-count":21,"publisher":"SAGE Publications","issue":"2","license":[{"start":{"date-parts":[[2025,8,29]],"date-time":"2025-08-29T00:00:00Z","timestamp":1756425600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2025,8,29]],"date-time":"2025-08-29T00:00:00Z","timestamp":1756425600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82372451"],"award-info":[{"award-number":["82372451"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Global Spine Journal"],"published-print":{"date-parts":[[2026,3]]},"abstract":"<jats:sec>\n                    <jats:title>Study Design<\/jats:title>\n                    <jats:p>Retrospective cohort study.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To describe the clinical characteristics and surgical outcomes of non-ambulatory patients with thoracic ossification of the posterior longitudinal ligament (T-OPLL), and to identify predictors of independent walking recovery.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This retrospective study analyzed 70 non-ambulatory T-OPLL patients treated with either circumferential decompression (CD) or posterior decompression with fusion (PDF) surgery at a single center over 10\u00a0years (2012-2022). Outcomes included neurological recovery rate, independent walking recovery, and complications.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Overall, 71.4% of patients regained independent walking. The CD group showed superior functional outcomes (90% vs 64% walking recovery,\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.030) but higher complication rates (70% vs 38% CSF leakage,\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.015). Shorter disease duration (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.018) and lower BMI (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.027) independently predicted better walking recovery.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>For non-ambulatory T-OPLL patients, CD surgery provides better functional recovery while PDF surgery offers a safer alternative. Early surgical intervention and individualized approach selection based on disease duration and BMI are critical for optimizing outcomes.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/21925682251374669","type":"journal-article","created":{"date-parts":[[2025,8,30]],"date-time":"2025-08-30T00:23:10Z","timestamp":1756513390000},"page":"1156-1164","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":1,"title":["Balancing Efficacy and Safety for Non-ambulatory Thoracic OPLL: Superior Mobility with Circumferential Decompression but Higher Risks \u2013 A Retrospective Analysis"],"prefix":"10.1177","volume":"16","author":[{"ORCID":"https:\/\/orcid.org\/0009-0002-5891-0536","authenticated-orcid":false,"given":"Juncai","family":"Lei","sequence":"first","affiliation":[{"name":"Peking University Third Hospital"},{"name":"Beijing Key Laboratory of Spinal Diseases, Peking University, Beijing, China"},{"name":"Engineering 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China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hua","family":"Zhou","sequence":"additional","affiliation":[{"name":"Peking University Third Hospital"},{"name":"Beijing Key Laboratory of Spinal Diseases, Peking University, Beijing, China"},{"name":"Engineering Research Center of Bone and Joint Precision Medicine, Peking University, Beijing, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yanchao","family":"Tang","sequence":"additional","affiliation":[{"name":"Peking University Third Hospital"},{"name":"Beijing Key Laboratory of Spinal Diseases, Peking University, Beijing, China"},{"name":"Engineering Research Center of Bone and Joint Precision Medicine, Peking University, Beijing, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tiantian","family":"Li","sequence":"additional","affiliation":[{"name":"Peking University Third Hospital"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ben","family":"Wang","sequence":"additional","affiliation":[{"name":"Peking University Third Hospital"},{"name":"Beijing Key Laboratory of Spinal Diseases, Peking University, Beijing, China"},{"name":"Engineering Research Center of Bone and Joint Precision Medicine, Peking University, Beijing, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yan","family":"Li","sequence":"additional","affiliation":[{"name":"Peking University Third Hospital"},{"name":"Beijing Key Laboratory of Spinal Diseases, Peking University, Beijing, China"},{"name":"Engineering Research Center of Bone and Joint Precision Medicine, Peking University, Beijing, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fengliang","family":"Wu","sequence":"additional","affiliation":[{"name":"Peking University Third Hospital"},{"name":"Beijing Key Laboratory of Spinal Diseases, Peking University, Beijing, China"},{"name":"Engineering Research Center of Bone and Joint Precision Medicine, Peking University, Beijing, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Liang","family":"Jiang","sequence":"additional","affiliation":[{"name":"Peking University Third Hospital"},{"name":"Beijing Key Laboratory of Spinal Diseases, Peking University, Beijing, China"},{"name":"Engineering Research Center of Bone and Joint Precision Medicine, Peking University, Beijing, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lei","family":"Dang","sequence":"additional","affiliation":[{"name":"Peking University Third Hospital"},{"name":"Beijing Key Laboratory of Spinal Diseases, Peking University, Beijing, China"},{"name":"Engineering Research Center of Bone and Joint Precision Medicine, Peking University, Beijing, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhongjun","family":"Liu","sequence":"additional","affiliation":[{"name":"Peking 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