{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T18:37:41Z","timestamp":1791398261608,"version":"4.3.3"},"reference-count":32,"publisher":"SAGE Publications","issue":"5","license":[{"start":{"date-parts":[[2025,10,29]],"date-time":"2025-10-29T00:00:00Z","timestamp":1761696000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2025,10,29]],"date-time":"2025-10-29T00:00:00Z","timestamp":1761696000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Global Spine Journal"],"published-print":{"date-parts":[[2026,6]]},"abstract":"<jats:sec>\n                    <jats:title>Study Design<\/jats:title>\n                    <jats:p>Retrospective study.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>To compare region-specific VBQ scores and to evaluate their effectiveness in assessing bone quality in patients with lumbar degenerative diseases.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This study retrospectively included patients who underwent lumbar fusion surgery for lumbar degenerative diseases between April 2021 and January 2025. Region-specific VBQ scores (VBQ-anterior, VBQ-classic and VBQ-posterior), assessed using preoperative MRI. Hounsfield Unit (HU) values were also recorded. Receiver operating characteristic (ROC) curves were generated to assess the diagnostic accuracy. Pearson correlation analysis was performed to evaluate the associations between region-specific VBQ scores, HU values, and lumbar T-scores.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      A total of 329 eligible patients was included. VBQ-anterior demonstrated the highest scores, whereas VBQ-posterior exhibited significantly lower values. Furthermore, we evaluated the diagnostic accuracy of the three VBQ measurement approaches, as well as HU values, in identifying osteoporotic patients. The results revealed that HU values showed the highest area under the curve (AUC = 0.857), followed by VBQ-posterior (AUC = 0.825). In contrast, VBQ-anterior exhibited the lowest diagnostic accuracy (AUC = 0.735). Correlation analysis demonstrated that HU values had the strongest correlation with lumbar T-scores (r = 0.57,\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; 0.001), followed by VBQ-posterior (r = 0.49,\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; 0.001) and VBQ-classic (r = 0.37,\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; 0.001). VBQ-anterior showed the weakest correlation with T-scores (r = 0.24,\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; 0.001).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>VBQ scoring provides a simple and relatively accurate method for assessing bone quality in patients with lumbar degenerative diseases. However, region-specific variations exist and VBQ-posterior may demonstrate superior diagnostic accuracy.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/21925682251393637","type":"journal-article","created":{"date-parts":[[2025,10,29]],"date-time":"2025-10-29T18:47:37Z","timestamp":1761763657000},"page":"2070-2078","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":3,"title":["Evaluation of MRI-Based Region-specific Vertebral Bone Quality Score for Bone Mineral Density in Lumbar Fusion Surgery"],"prefix":"10.1177","volume":"16","author":[{"ORCID":"https:\/\/orcid.org\/0009-0006-3490-9142","authenticated-orcid":false,"given":"Xuan","family":"Zhao","sequence":"first","affiliation":[{"name":"Department of Orthopedics, Xuanwu Hospital, Capital Medical University, National Clinical Research Center for Geriatric Diseases, Beijing, China"},{"name":"Capital Medical University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wei","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Orthopedics, Xuanwu Hospital, Capital Medical University, National Clinical Research Center for Geriatric Diseases, Beijing, China"},{"name":"Capital Medical University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaolong","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Orthopedics, Xuanwu Hospital, Capital Medical University, National Clinical Research Center for Geriatric Diseases, Beijing, China"},{"name":"Capital Medical University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shibao","family":"Lu","sequence":"additional","affiliation":[{"name":"Department of Orthopedics, Xuanwu Hospital, Capital Medical University, National Clinical Research Center for Geriatric Diseases, Beijing, China"},{"name":"Capital Medical University"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2025,10,29]]},"reference":[{"key":"e_1_3_6_2_2","doi-asserted-by":"publisher","DOI":"10.1177\/2192568218770769"},{"key":"e_1_3_6_3_2","doi-asserted-by":"publisher","DOI":"10.3171\/2024.9.SPINE24858"},{"key":"e_1_3_6_4_2","doi-asserted-by":"publisher","DOI":"10.1097\/BRS.0000000000004577"},{"key":"e_1_3_6_5_2","doi-asserted-by":"publisher","DOI":"10.1177\/21925682211017477"},{"key":"e_1_3_6_6_2","first-page":"1","article-title":"Sex differences in the accuracy of vertebral bone quality score assessing bone density in patients undergoing lumbar spinal fusion","volume":"40","author":"Wang Y","year":"2023","unstructured":"Wang Y, Wang F, Tong T, et al. 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