{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,24]],"date-time":"2026-10-24T01:55:09Z","timestamp":1792806909265,"version":"4.5.0"},"reference-count":36,"publisher":"SAGE Publications","issue":"6","license":[{"start":{"date-parts":[[2025,12,22]],"date-time":"2025-12-22T00:00:00Z","timestamp":1766361600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2025,12,22]],"date-time":"2025-12-22T00:00:00Z","timestamp":1766361600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Global Spine Journal"],"published-print":{"date-parts":[[2026,7]]},"abstract":"<jats:sec>\n                    <jats:title>Study Design<\/jats:title>\n                    <jats:p>Randomized Controlled Trial.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Background and Objectives<\/jats:title>\n                    <jats:p>The Schroth method has emerged as a promising rehabilitation approach for Adolescent Idiopathic Scoliosis (AIS). This study compared the effects of Schroth and conventional exercise programs on spinal curvature, cortical thickness, and white matter pathways using structural MRI and Diffusion Tensor Imaging (DTI).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      Thirty-six individuals with AIS were randomly assigned to a Schroth Exercise Group (SEG) or a Traditional Exercise Group (TEG). A healthy control group (n = 18) was also included. The sample size was calculated to provide 80% power (d = 0.60), and post hoc analysis indicated strong power (&gt;0.99) for the observed treatment effect (d = 3.59). Both exercise groups completed supervised home-based programs for four months. Post-intervention MRI and DTI analyses were performed. The study was registered at\n                      <jats:ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"uri\" xlink:href=\"https:\/\/clinicaltrials.gov\/\">ClinicalTrials.gov<\/jats:ext-link>\n                      (NCT06410456).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      After adjusting for baseline severity, the SEG showed a significantly greater improvement in Cobb angle compared to the TEG (adjusted mean difference = 8.07\u00b0,\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; .001). Although the SEG achieved a significantly lower post-treatment Cobb angle compared to the TEG, residual curvature remained significantly different from the healthy controls (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; .001), reflecting the structural nature of scoliosis. Additionally, after adjusting for age and intracranial volume, cortical thickness in sensorimotor regions and tractography metrics of the right corticospinal tract in the SEG were comparable to controls and significantly different from the TEG.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Schroth exercises were associated with brain structural features suggestive of adaptive neuroplastic responses. These exploratory findings highlight potential neurobiological mechanisms and support further longitudinal research.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/21925682251411247","type":"journal-article","created":{"date-parts":[[2025,12,22]],"date-time":"2025-12-22T09:10:39Z","timestamp":1766394639000},"page":"2588-2600","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":2,"title":["Associations Between Different Exercise Approaches and Brain Structure in Adolescent Idiopathic Scoliosis: An Exploratory Neuroimaging Study"],"prefix":"10.1177","volume":"16","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1629-9794","authenticated-orcid":false,"given":"Ahmet","family":"Payas","sequence":"first","affiliation":[{"name":"Amasya University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hikmet","family":"Kocaman","sequence":"additional","affiliation":[{"name":"Karamanoglu Mehmetbey University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hasan","family":"Y\u0131ld\u0131r\u0131m","sequence":"additional","affiliation":[{"name":"Karamano\u011flu Mehmetbey University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5596-9175","authenticated-orcid":false,"given":"Mustafa","family":"Ar\u0131k","sequence":"additional","affiliation":[{"name":"Kayseri Public Hospital"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sabri","family":"Bat\u0131n","sequence":"additional","affiliation":[{"name":"Kayseri City Education and Training Hospital Orthopedics and Traumatology Department, University of Health Sciences, Kayseri, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2025,12,22]]},"reference":[{"key":"e_1_3_5_2_2","doi-asserted-by":"publisher","DOI":"10.3390\/ijerph192416730"},{"key":"e_1_3_5_3_2","doi-asserted-by":"publisher","DOI":"10.1038\/nrdp.2015.30"},{"key":"e_1_3_5_4_2","doi-asserted-by":"publisher","DOI":"10.1002\/jsp2.1355"},{"key":"e_1_3_5_5_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00586-024-08524-y"},{"key":"e_1_3_5_6_2","doi-asserted-by":"publisher","DOI":"10.1097\/CM9.0000000000000652"},{"key":"e_1_3_5_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroimage.2011.07.097"},{"key":"e_1_3_5_8_2","doi-asserted-by":"publisher","DOI":"10.5546\/aap.2018.eng.e582"},{"key":"e_1_3_5_9_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00586-022-07407-4"},{"key":"e_1_3_5_10_2","doi-asserted-by":"publisher","DOI":"10.1097\/BRS.0b013e31819c9431"},{"key":"e_1_3_5_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.apmr.2024.04.011"},{"key":"e_1_3_5_12_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0249492"},{"key":"e_1_3_5_13_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cortex.2014.05.001"},{"key":"e_1_3_5_14_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jchemneu.2023.102250"},{"key":"e_1_3_5_15_2","doi-asserted-by":"publisher","DOI":"10.1146\/annurev-psych-010814-015340"},{"key":"e_1_3_5_16_2","doi-asserted-by":"publisher","DOI":"10.1097\/CORR.0000000000000405"},{"key":"e_1_3_5_17_2","doi-asserted-by":"publisher","DOI":"10.1097\/BPO.0000000000002300"},{"key":"e_1_3_5_18_2","doi-asserted-by":"publisher","DOI":"10.1002\/brb3.3320"},{"key":"e_1_3_5_19_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0286280"},{"key":"e_1_3_5_20_2","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2342-12-30"},{"key":"e_1_3_5_21_2","doi-asserted-by":"publisher","DOI":"10.1186\/s13013-015-0048-5"},{"key":"e_1_3_5_22_2","doi-asserted-by":"publisher","DOI":"10.3390\/healthcare13060688"},{"issue":"3","key":"e_1_3_5_23_2","first-page":"193","article-title":"Adolescent idiopathic scoliosis: diagnosis and management","volume":"89","author":"Horne JP","year":"2014","unstructured":"Horne JP, Flannery R, Usman S. 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