{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,28]],"date-time":"2026-09-28T10:00:24Z","timestamp":1790589624811,"version":"4.1.0"},"reference-count":17,"publisher":"SAGE Publications","issue":"7","license":[{"start":{"date-parts":[[2026,2,5]],"date-time":"2026-02-05T00:00:00Z","timestamp":1770249600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,2,5]],"date-time":"2026-02-05T00:00:00Z","timestamp":1770249600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Global Spine Journal"],"published-print":{"date-parts":[[2026,9]]},"abstract":"<jats:sec>\n                    <jats:title>Study Design<\/jats:title>\n                    <jats:p>Retrospective Cohort Study.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>To compare 1-year postoperative outcomes and complication rates between single-level lumbar laminectomy and hemilaminectomy using a large, multicenter, propensity-matched dataset.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We queried the TriNetX global health research network (\u2265160 million patients) for adults undergoing single-level lumbar decompression between January 2005 and July 2025. Cohorts were defined by CPT codes: laminectomy and hemilaminectomy, with qualifying diagnoses of lumbar disc herniation, spinal stenosis, spondylolisthesis, or radiculopathy. Patients with fusion, prior lumbar surgery, or non-degenerative pathology were excluded. Outcomes included new postoperative events within 1\u00a0year: mortality, weakness, pain, sensory loss, cauda equina syndrome, radiculopathy, foot drop, CSF leak, and surgical-site infection. Propensity-score matching balanced demographics and comorbidities. Cox proportional hazards models, Kaplan\u2013Meier curves, and relative risks were calculated.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Of 167,177 patients, 80,440 underwent laminectomy and 86,737 hemilaminectomy. After matching, 50,853 patients per cohort were analyzed. One-year mortality was similar (0.57% vs 0.49%, HR 1.20; 95% CI 1.01-1.42;\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.045). Laminectomy conferred significantly higher risks of CSF leak (1.41% vs 1.00%; RR 1.41), surgical-site infection (1.45% vs 1.00%; RR 1.45), cauda equina syndrome (0.36% vs 0.22%; RR 1.62), and persistent weakness (4.12% vs 3.67%; RR 1.12). Persistent radiculopathy was modestly less frequent after laminectomy (10.5% vs 12.0%; RR 0.87). Other outcomes, including pain and foot drop, were comparable.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Hemilaminectomy was associated with lower perioperative complication rates compared to laminectomy, while laminectomy provided a modest reduction in persistent radiculopathy. These findings highlight a tradeoff between safety and decompressive efficacy, emphasizing the importance of patient-specific surgical selection.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/21925682261424530","type":"journal-article","created":{"date-parts":[[2026,2,5]],"date-time":"2026-02-05T15:33:29Z","timestamp":1770305609000},"page":"3148-3154","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":1,"title":["Comparative Outcomes of Single-Level Lumbar Laminectomy versus Hemilaminectomy: A Retrospective TriNetX Analysis"],"prefix":"10.1177","volume":"16","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9091-5818","authenticated-orcid":false,"given":"Christopher","family":"Sollenberger","sequence":"first","affiliation":[{"name":"University of Pennsylvania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Albert Q.","family":"Wu","sequence":"additional","affiliation":[{"name":"University of Pennsylvania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0008-6490-9957","authenticated-orcid":false,"given":"Zachary","family":"Hoglund","sequence":"additional","affiliation":[{"name":"University of Pennsylvania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Varun G.","family":"Kathawate","sequence":"additional","affiliation":[{"name":"University of Pennsylvania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"William","family":"Welch","sequence":"additional","affiliation":[{"name":"University of Pennsylvania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ali","family":"Ozturk","sequence":"additional","affiliation":[{"name":"University of Pennsylvania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John","family":"Shin","sequence":"additional","affiliation":[{"name":"University of Pennsylvania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brendan F.","family":"Judy","sequence":"additional","affiliation":[{"name":"University of Pennsylvania"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2026,2,5]]},"reference":[{"key":"e_1_3_7_2_2","doi-asserted-by":"publisher","DOI":"10.21037\/jss.2017.10.08"},{"key":"e_1_3_7_3_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00586-025-08953-3"},{"key":"e_1_3_7_4_2","doi-asserted-by":"publisher","DOI":"10.1631\/jzus.B1000402"},{"key":"e_1_3_7_5_2","doi-asserted-by":"publisher","DOI":"10.1097\/BRS.0b013e3181c9b8d6"},{"key":"e_1_3_7_6_2","doi-asserted-by":"publisher","DOI":"10.1097\/01.brs.0000144408.02918.20"},{"key":"e_1_3_7_7_2","doi-asserted-by":"publisher","DOI":"10.3171\/2015.7.Focus15259"},{"key":"e_1_3_7_8_2","doi-asserted-by":"publisher","DOI":"10.1093\/neuros\/nyw091"},{"key":"e_1_3_7_9_2","doi-asserted-by":"publisher","DOI":"10.1111\/os.12184"},{"key":"e_1_3_7_10_2","doi-asserted-by":"publisher","DOI":"10.1097\/brs.0000000000001161"},{"key":"e_1_3_7_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.wneu.2025.124031"},{"key":"e_1_3_7_12_2","doi-asserted-by":"publisher","DOI":"10.1055\/s-0041-1722968"},{"key":"e_1_3_7_13_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00586-014-3349-0"},{"key":"e_1_3_7_14_2","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD010036.pub2"},{"key":"e_1_3_7_15_2","volume-title":"Reader Response: Efficacy and Safety of IV Thrombolysis for Acute Ischemic Stroke Patients with Moyamoya Disease","author":"Wu A","year":"2025","unstructured":"Wu A, Davis P, Scott K, Catapano J, Burkhardt J-K, Srinivasan V. Reader Response: Efficacy and Safety of IV Thrombolysis for Acute Ischemic Stroke Patients with Moyamoya Disease; 2025."},{"key":"e_1_3_7_16_2","doi-asserted-by":"publisher","DOI":"10.1212\/wnl.0000000000210243"},{"key":"e_1_3_7_17_2","doi-asserted-by":"publisher","DOI":"10.3389\/fphar.2025.1516126"},{"key":"e_1_3_7_18_2","doi-asserted-by":"publisher","DOI":"10.1093\/jamiaopen\/ooad035"}],"container-title":["Global Spine Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/21925682261424530","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/21925682261424530","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/21925682261424530","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,28]],"date-time":"2026-09-28T09:52:38Z","timestamp":1790589158000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/21925682261424530"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,2,5]]},"references-count":17,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2026,9]]}},"alternative-id":["10.1177\/21925682261424530"],"URL":"https:\/\/doi.org\/10.1177\/21925682261424530","relation":{},"ISSN":["2192-5682","2192-5690"],"issn-type":[{"value":"2192-5682","type":"print"},{"value":"2192-5690","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,2,5]]}}}