{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,3]],"date-time":"2026-07-03T20:20:48Z","timestamp":1783110048390,"version":"3.54.6"},"reference-count":76,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2026,6,29]],"date-time":"2026-06-29T00:00:00Z","timestamp":1782691200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2026,6,29]],"date-time":"2026-06-29T00:00:00Z","timestamp":1782691200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Global Spine Journal"],"abstract":"<jats:sec>\n                    <jats:title>Study design<\/jats:title>\n                    <jats:p>Systematic review and meta-analysis of randomized controlled trials and cohort studies directly comparing full-endoscopic posterior cervical decompression (PECD) with anterior cervical discectomy and fusion (ACDF) in adults with degenerative cervical disease.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To compare full-endoscopic posterior cervical decompression with anterior cervical discectomy and fusion for degenerative cervical disease.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>PubMed, Embase, and CENTRAL were searched through September 2025 for randomized and cohort studies in adults with \u2265 6 months\u2019 follow-up directly comparing PECD and ACDF. NDI, VAS neck\/arm pain in short-term and long-term follow up, C2\u2013C7 Cobb angle, peri-operative metrics, and adverse events were pooled using random-effects models with 95% confidence intervals.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Ten studies (2 RCTs, 8 cohorts) comprising 862 patients (PECD 433; ACDF 429) with 6 months to 2.5 years of follow-up were included. NDI and VAS arm pain scores did not differ significantly at final follow-up. PECD showed greater short-term functional improvement (NDI MD 2.46, 95% CI 1.55\u20133.36), whereas ACDF achieved slightly greater long-term neck pain improvement (VAS neck MD \u22120.24, 95% CI \u22120.43 to \u22120.04). C2\u2013C7 Cobb angle and operative time did not differ. PECD was associated with a shorter hospital stay (MD \u22121.64 days, 95% CI \u22122.31 to \u22120.97) and lower blood loss (MD \u221244.85 mL, 95% CI \u221279.8 to \u22129.89), though these perioperative outcomes demonstrated substantial heterogeneity. Additionally, PECD was associated with a significantly lower risk of postoperative complications (RR 0.53, 95% CI 0.34\u20130.81); whereas ASD and index-level re-operation rate did not differ.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>PECD provides comparable mid-term disability and arm pain relief to ACDF with faster early recovery and lower perioperative morbidity, while ACDF offers marginally better long-term axial neck pain improvement.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/21925682261464552","type":"journal-article","created":{"date-parts":[[2026,6,29]],"date-time":"2026-06-29T09:28:31Z","timestamp":1782725311000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Full-Endoscopic Posterior Cervical Decompression Versus Anterior Cervical Discectomy and Fusion: A Systematic Review and Meta-Analysis"],"prefix":"10.1177","author":[{"ORCID":"https:\/\/orcid.org\/0009-0006-9828-5631","authenticated-orcid":false,"given":"Chi-Chin","family":"Huang","sequence":"first","affiliation":[{"name":"Taipei Medical University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0001-1734-1552","authenticated-orcid":false,"given":"Yu-San","family":"Chen","sequence":"additional","affiliation":[{"name":"Shuang Ho Hospital"},{"name":"Taipei Medical University"},{"name":"National Yang Ming Chiao Tung University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6743-4717","authenticated-orcid":false,"given":"Yueh-Ying","family":"Hsieh","sequence":"additional","affiliation":[{"name":"Shuang Ho Hospital"},{"name":"Taipei Medical University"},{"name":"Hsin Kuo Min Hospital"},{"name":"Taipei Medical University"},{"name":"Department of Orthopedics, School of Medicine, College of Medicine, 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