{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,13]],"date-time":"2026-07-13T17:06:48Z","timestamp":1783962408982,"version":"3.55.0"},"reference-count":40,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2026,7,10]],"date-time":"2026-07-10T00:00:00Z","timestamp":1783641600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2026,7,10]],"date-time":"2026-07-10T00:00:00Z","timestamp":1783641600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Global Spine Journal"],"abstract":"<jats:sec>\n                    <jats:title>Study Design<\/jats:title>\n                    <jats:p>Systematic review.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>To synthesize outcomes, complications, and healthcare utilization after surgery for degenerative cervical myelopathy (DCM) in patients with Parkinson disease (PD).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>PubMed\/MEDLINE, EMBASE, and the Cochrane Library were searched from inception to March 2026. Eligible studies evaluated adults with PD undergoing cervical decompression with or without fusion for DCM; studies not specifically defining myelopathy but reporting cervical outcomes within broader PD spine cohorts were retained as indirect supportive evidence. Two reviewers independently screened studies, extracted data, and appraised quality using standard checklists. Because of marked heterogeneity, findings were synthesized narratively, with greater weight given to myelopathy-defined cohorts.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Eleven studies were included: 5 myelopathy-defined cohorts and 6 supportive studies. In myelopathy-defined cohorts, PD patients improved after surgery, but some studies showed smaller gains in modified Japanese Orthopaedic Association (mJOA) or Nurick scores, lower odds of clinically important mJOA improvement, and less EQ-5D improvement compared with non-PD controls. Database studies showed higher complication rates, longer hospital stays, non-home discharge, and a dysphagia\/aspiration signal. Supportive studies suggested similar increases in hospitalization and medical complications and raised concern for long-term mechanical failure or reoperation.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>The most direct evidence suggests that patients with PD undergoing surgery for cervical myelopathy may improve neurologically, although functional recovery may be smaller or less clinically meaningful in some cohorts. Perioperative risk and healthcare utilization also appear higher. Indirect supportive evidence further suggests that dysphagia or aspiration-related events and long-term mechanical failure or reoperation are important concerns in this population.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/21925682261468270","type":"journal-article","created":{"date-parts":[[2026,7,10]],"date-time":"2026-07-10T07:11:06Z","timestamp":1783667466000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Surgical Outcomes of Degenerative Cervical Myelopathy in Patients with Parkinson Disease: A Systematic Review"],"prefix":"10.1177","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9956-5914","authenticated-orcid":false,"given":"Shota","family":"Takenaka","sequence":"first","affiliation":[{"name":"Japan Community Healthcare Organization Osaka Hospital"},{"name":"Guideline Committee of Cervical Spondylotic Myelopathy, The Japanese Orthopaedic Association"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7834-1727","authenticated-orcid":false,"given":"Hiroyuki","family":"Ishiguro","sequence":"additional","affiliation":[{"name":"National Hospital Organization Osaka Medical Center"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3511-9020","authenticated-orcid":false,"given":"Toshitaka","family":"Yoshii","sequence":"additional","affiliation":[{"name":"Guideline Committee of Cervical Spondylotic Myelopathy, The Japanese Orthopaedic Association"},{"name":"Institute of Science Tokyo"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kentaro","family":"Yamada","sequence":"additional","affiliation":[{"name":"Guideline Committee of Cervical Spondylotic Myelopathy, The Japanese Orthopaedic Association"},{"name":"Institute of Science Tokyo"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eiji","family":"Takasawa","sequence":"additional","affiliation":[{"name":"Guideline Committee of Cervical Spondylotic Myelopathy, The Japanese Orthopaedic Association"},{"name":"Graduate School of Medicine, Gunma University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Satoshi","family":"Nori","sequence":"additional","affiliation":[{"name":"Guideline Committee of Cervical Spondylotic Myelopathy, The Japanese Orthopaedic Association"},{"name":"National Hospital Organization Tokyo Medical Center"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"So","family":"Kato","sequence":"additional","affiliation":[{"name":"Guideline Committee of Cervical Spondylotic Myelopathy, The Japanese Orthopaedic Association"},{"name":"The University of Tokyo"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0117-4152","authenticated-orcid":false,"given":"Kazuya","family":"Kitamura","sequence":"additional","affiliation":[{"name":"Guideline Committee of Cervical Spondylotic Myelopathy, The Japanese Orthopaedic Association"},{"name":"National Defense Medical College"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5378-940X","authenticated-orcid":false,"given":"Takeo","family":"Furuya","sequence":"additional","affiliation":[{"name":"Guideline Committee of Cervical Spondylotic Myelopathy, The Japanese Orthopaedic Association"},{"name":"Chiba Kaihin Municipal Hospital"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiroaki","family":"Nakashima","sequence":"additional","affiliation":[{"name":"Guideline Committee of Cervical Spondylotic Myelopathy, The Japanese Orthopaedic Association"},{"name":"Nagoya University Graduate School of Medicine"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Norimitsu","family":"Wakao","sequence":"additional","affiliation":[{"name":"Guideline Committee of Cervical Spondylotic Myelopathy, The Japanese Orthopaedic Association"},{"name":"Aichi Medical University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kazuyoshi","family":"Nakanishi","sequence":"additional","affiliation":[{"name":"Guideline Committee of Cervical Spondylotic Myelopathy, The Japanese Orthopaedic Association"},{"name":"Nihon University School of Medicine"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yasushi","family":"Fujiwara","sequence":"additional","affiliation":[{"name":"Guideline Committee of Cervical Spondylotic Myelopathy, The Japanese Orthopaedic Association"},{"name":"Hiroshima City North Medical Center Asa Citizens Hospital"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masahiro","family":"Yoshida","sequence":"additional","affiliation":[{"name":"Guideline Committee of Cervical Spondylotic Myelopathy, The Japanese Orthopaedic Association"},{"name":"International University of Health and Welfare, School of Medicine"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masahiko","family":"Watanabe","sequence":"additional","affiliation":[{"name":"Guideline Committee of Cervical Spondylotic Myelopathy, The Japanese Orthopaedic Association"},{"name":"Tokai University School of Medicine"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hirotaka","family":"Chikuda","sequence":"additional","affiliation":[{"name":"Guideline Committee of Cervical Spondylotic Myelopathy, The Japanese Orthopaedic Association"},{"name":"Graduate School of Medicine, Gunma University"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2026,7,10]]},"reference":[{"key":"e_1_3_7_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(21)00218-X"},{"key":"e_1_3_7_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(06)70471-9"},{"key":"e_1_3_7_4_2","doi-asserted-by":"publisher","DOI":"10.1002\/mds.27063"},{"key":"e_1_3_7_5_2","doi-asserted-by":"publisher","DOI":"10.1080\/02688697.2024.2374581"},{"key":"e_1_3_7_6_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41582-019-0303-0"},{"key":"e_1_3_7_7_2","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.k186"},{"key":"e_1_3_7_8_2","doi-asserted-by":"publisher","DOI":"10.1615\/JLongTermEffMedImplants.2016013363"},{"key":"e_1_3_7_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.clineuro.2015.04.022"},{"key":"e_1_3_7_10_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00586-010-1405-y"},{"key":"e_1_3_7_11_2","doi-asserted-by":"publisher","DOI":"10.1097\/01.brs.0000138306.02425.21"},{"key":"e_1_3_7_12_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00586-024-08307-5"},{"key":"e_1_3_7_13_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.wneu.2022.10.065"},{"key":"e_1_3_7_14_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.xnsj.2025.100808"},{"key":"e_1_3_7_15_2","doi-asserted-by":"publisher","DOI":"10.3390\/brainsci7040039"},{"key":"e_1_3_7_16_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijsu.2021.105906"},{"key":"e_1_3_7_17_2","article-title":"Surgical management of degenerative cervical myelopathy in patients with Parkinson\u2019s disease: a systematic review protocol with structured narrative synthesis (SWiM)","author":"Takenaka S","year":"2026","unstructured":"Takenaka S, Ishiguro H, Yoshii T, et al. Surgical management of degenerative cervical myelopathy in patients with Parkinson\u2019s disease: a systematic review protocol with structured narrative synthesis (SWiM). Registered March 11, 2026. OSF Registries. 2026. https:\/\/doi.org\/10.17605\/OSF.IO\/RQN3J. Accessed May 31, 2026.","journal-title":"OSF Registries"},{"key":"e_1_3_7_18_2","doi-asserted-by":"publisher","DOI":"10.46658\/JBIMES-20-08"},{"key":"e_1_3_7_19_2","doi-asserted-by":"publisher","DOI":"10.1093\/neuros\/nyw043"},{"key":"e_1_3_7_20_2","doi-asserted-by":"publisher","DOI":"10.1097\/BRS.0000000000004401"},{"key":"e_1_3_7_21_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.spinee.2016.07.530"},{"key":"e_1_3_7_22_2","doi-asserted-by":"publisher","DOI":"10.1093\/neuros\/nyz087"},{"key":"e_1_3_7_23_2","doi-asserted-by":"publisher","DOI":"10.1097\/BSD.0000000000001197"},{"key":"e_1_3_7_24_2","doi-asserted-by":"publisher","DOI":"10.1097\/BSD.0000000000001233"},{"key":"e_1_3_7_25_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.wneu.2019.08.114"},{"key":"e_1_3_7_26_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.xnsj.2022.100164"},{"key":"e_1_3_7_27_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.wneu.2022.06.081"},{"issue":"1","key":"e_1_3_7_28_2","first-page":"62","article-title":"[Analysis of long-time construct failure of spinal surgery in patients with Parkinson\u2019s disease]","volume":"91","author":"Liu ZW","year":"2011","unstructured":"Liu ZW, Yan WH, Qiu XB, Xu P. [Analysis of long-time construct failure of spinal surgery in patients with Parkinson\u2019s disease]. Zhonghua Yi Xue Za Zhi. 2011;91(1):62\u201364. (in Chinese).","journal-title":"Zhonghua Yi Xue Za Zhi"},{"key":"e_1_3_7_29_2","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/119.2.551"},{"key":"e_1_3_7_30_2","doi-asserted-by":"publisher","DOI":"10.1063\/1.3147408"},{"key":"e_1_3_7_31_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00415-019-09382-1"},{"key":"e_1_3_7_32_2","doi-asserted-by":"publisher","DOI":"10.21037\/jss-21-109"},{"key":"e_1_3_7_33_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.spinee.2023.09.030"},{"key":"e_1_3_7_34_2","doi-asserted-by":"publisher","DOI":"10.1212\/wnl.17.5.427"},{"key":"e_1_3_7_35_2","doi-asserted-by":"publisher","DOI":"10.1002\/mds.22340"},{"key":"e_1_3_7_36_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-1331.2008.02056.x"},{"key":"e_1_3_7_37_2","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.0000000000200113"},{"key":"e_1_3_7_38_2","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.0b013e3181fef115"},{"key":"e_1_3_7_39_2","doi-asserted-by":"publisher","DOI":"10.1177\/21925682211057484"},{"key":"e_1_3_7_40_2","doi-asserted-by":"publisher","DOI":"10.3390\/biomedicines10102621"},{"key":"e_1_3_7_41_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.spinee.2023.09.006"}],"container-title":["Global Spine Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/21925682261468270","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/21925682261468270","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/21925682261468270","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,13]],"date-time":"2026-07-13T16:21:29Z","timestamp":1783959689000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/21925682261468270"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,7,10]]},"references-count":40,"alternative-id":["10.1177\/21925682261468270"],"URL":"https:\/\/doi.org\/10.1177\/21925682261468270","relation":{},"ISSN":["2192-5682","2192-5690"],"issn-type":[{"value":"2192-5682","type":"print"},{"value":"2192-5690","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,7,10]]},"article-number":"21925682261468270"}}