{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,31]],"date-time":"2026-08-31T22:27:13Z","timestamp":1788215233657,"version":"build-2803163510"},"reference-count":22,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2026,7,27]],"date-time":"2026-07-27T00:00:00Z","timestamp":1785110400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2026,7,27]],"date-time":"2026-07-27T00:00:00Z","timestamp":1785110400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Global Spine Journal"],"abstract":"<jats:sec>\n                    <jats:title>Study Design<\/jats:title>\n                    <jats:p>Retrospective National Cohort Study.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>This study aimed to evaluate complication profiles in myasthenia gravis (MG) versus non-MG patients across four routine spine surgeries: lumbar interbody fusion (LIF), lumbar decompression (LD), anterior cervical discectomy and fusion (ACDF), and posterior cervical decompression and fusion (PCDF).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>From 2010 to 2023, all LIF, LD, ACDF, or PCDF patients were queried from the PearlDiver Mariner Database using ICD-9\/10 and CPT procedure codes. MG patients with prior thymectomy were excluded. Nearest-neighbor 3:1 propensity score matching based on age, sex, and comorbidity burden was performed. Postoperative complication rates were assessed during index hospitalization and 90 days postoperatively.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Among those included, 829, 1198, 527, and 129 MG patients underwent LIF, LD, ACDF, and PCDF, respectively. Understandably, MG patients had elevated rates of myasthenic crisis (5.4-8.5%) across all four cohorts at both time points. During initial hospital stay, MG patients had increased rates of pneumonia (4.0% vs 2.3%, p=0.017) and respiratory failure (4.9% vs 3.3%, p=0.016) following LIF and LD, respectively. Conversely, ACDF MG patients had decreased rates of CVA (0.9% vs 2.7%, p=0.028) and AKI (1.3% vs 3.5%, p=0.017). Similar trends were observed 90 days postoperatively. Length of stay was comparable across cohorts.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Myasthenia gravis patients undergoing routine spine surgery face elevated risk of respiratory complications postoperatively. Other systemic complications rates were comparable following matching suggesting complication profiles may be surgery-specific rather than uniformly increased with MG. Appropriate preoperative optimization and multidisciplinary perioperative management allows for safe spine surgery in MG patients.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/21925682261474155","type":"journal-article","created":{"date-parts":[[2026,7,27]],"date-time":"2026-07-27T20:49:05Z","timestamp":1785185345000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":1,"title":["Postoperative Complications Following Spine Surgery in Myasthenia Gravis Patients: A Propensity-Matched National Database Analysis"],"prefix":"10.1177","author":[{"ORCID":"https:\/\/orcid.org\/0009-0005-5916-0484","authenticated-orcid":false,"given":"Daniel","family":"Rusu","sequence":"first","affiliation":[{"name":"Keck School of Medicine of the University of Southern California"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0009-8110-9211","authenticated-orcid":false,"given":"Aidan R.","family":"Lindgren","sequence":"additional","affiliation":[{"name":"Keck School of Medicine of the University of Southern California"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7987-256X","authenticated-orcid":false,"given":"Mirbahador","family":"Athari","sequence":"additional","affiliation":[{"name":"Keck School of Medicine of the University of Southern California"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8300-2452","authenticated-orcid":false,"given":"Maya S.","family":"Abu-Zahra","sequence":"additional","affiliation":[{"name":"Keck School of Medicine of the University of Southern California"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Niels","family":"Mohty","sequence":"additional","affiliation":[{"name":"Keck School of Medicine of the University of Southern California"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3294-4001","authenticated-orcid":false,"given":"Marc A.","family":"Abdou","sequence":"additional","affiliation":[{"name":"Keck School of Medicine of the University of Southern California"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0004-4021-3219","authenticated-orcid":false,"given":"Joshua","family":"Davood","sequence":"additional","affiliation":[{"name":"Keck School of Medicine of the University of Southern California"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeffrey C.","family":"Wang","sequence":"additional","affiliation":[{"name":"Keck School of Medicine of the University of Southern California"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7513-3519","authenticated-orcid":false,"given":"Raymond 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