{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,3]],"date-time":"2026-05-03T23:36:52Z","timestamp":1777851412508,"version":"3.51.4"},"reference-count":0,"publisher":"SAGE Publications","issue":"7","license":[{"start":{"date-parts":[[1974,7,1]],"date-time":"1974-07-01T00:00:00Z","timestamp":141868800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Histochem Cytochem."],"published-print":{"date-parts":[[1974,7]]},"abstract":"<jats:p>\n                    Fluorescent staining for intracellular deoxyribonucleic acid content is being investigated as a means of making automated measurements quantitative and reliable. Ambiguities regarding the role of sulfur dioxide in Feulgen staining chemistry have been resolved showing that: (a) SO\n                    <jats:sub>2<\/jats:sub>\n                    does not covalently bind to the anilinium moieties of pararosaniline; (b) SO\n                    <jats:sub>2<\/jats:sub>\n                    does promote the binding of pararosaniline within the nuclei of hydrolyzed cells; (c) SO\n                    <jats:sub>2<\/jats:sub>\n                    also does not bind to dyes such as acriflavine used in fluorescent-\"Feulgen\" staining and (d) SO\n                    <jats:sub>2<\/jats:sub>\n                    is not required for strong, nucleus-specific acriflavine staining of nuclei of hydrolyzed cells. These findings permit simplifications of the usual fluorescent-\"Feulgen\" procedures. Attempts to use fluorescent intercalating dyes as vital stains for deoxyribonucleic acid content have been unsuccessful.\n                  <\/jats:p>","DOI":"10.1177\/22.7.470","type":"journal-article","created":{"date-parts":[[2011,4,1]],"date-time":"2011-04-01T01:19:10Z","timestamp":1301620750000},"page":"470-477","source":"Crossref","is-referenced-by-count":25,"title":["DEOXYRIBONUCLEIC ACID CYTOCHEMISTRY FOR AUTOMATED CYTOLOGY"],"prefix":"10.1177","volume":"22","author":[{"given":"J. E.","family":"GILL","sequence":"first","affiliation":[{"name":"Bio-Medical Divison, Lawrence Livermore Laboratory, University of California, Livermore, California 94550"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M. M.","family":"JOTZ","sequence":"additional","affiliation":[{"name":"Bio-Medical Divison, Lawrence Livermore Laboratory, University of California, Livermore, California 94550"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[1974,7,1]]},"container-title":["Journal of Histochemistry &amp; Cytochemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/22.7.470","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/22.7.470","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T22:21:00Z","timestamp":1777501260000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/22.7.470"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1974,7]]},"references-count":0,"journal-issue":{"issue":"7","published-print":{"date-parts":[[1974,7]]}},"alternative-id":["10.1177\/22.7.470"],"URL":"https:\/\/doi.org\/10.1177\/22.7.470","relation":{},"ISSN":["0022-1554","1551-5044"],"issn-type":[{"value":"0022-1554","type":"print"},{"value":"1551-5044","type":"electronic"}],"subject":[],"published":{"date-parts":[[1974,7]]}}}