{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,4]],"date-time":"2026-09-04T11:19:41Z","timestamp":1788520781475,"version":"build-2803163510"},"reference-count":34,"publisher":"SAGE Publications","issue":"5","license":[{"start":{"date-parts":[[2026,1,8]],"date-time":"2026-01-08T00:00:00Z","timestamp":1767830400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2026,1,8]],"date-time":"2026-01-08T00:00:00Z","timestamp":1767830400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"DOI":"10.13039\/100001411","name":"King Baudouin Foundation United States","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100001411","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100013465","name":"French Muscular Dystrophy Association","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100013465","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Journal of Neuromuscular Diseases"],"published-print":{"date-parts":[[2026,9]]},"abstract":"<jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>Neuromuscular diseases (NMD) cause progressive muscle weakness, significantly impairing functional abilities. Light powered assistive devices hold strong promises for improving mobility and independence in NMD. The current work investigated the efficacy and biomechanical effects of the MyoSuit that provides assistance during functional tasks, by supporting hips and knees.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>Seventeen adults with NMD studied during a 2-min walk test, a 10-meter walk test, and a 30-s sit-to-stand test with and without using the MyoSuit. Muscle activation, joint kinematics, and spatio-temporal gait parameters were recorded.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      Knee extensor and hip extensor strength were 22.8\u2009\u00b1\u200942.9% and 71.2\u2009\u00b1\u200958.2% of predicted force, respectively. 2MWT was 76.3\u2009\u00b1\u200925.1% of predicted distance. Walking and sit-to-stand performances were reduced. Significantly, cadence, and stride length decreased, while step duration increased. Muscle activation showed decreased\n                      <jats:italic toggle=\"yes\">rectus femoris<\/jats:italic>\n                      and altered timing in\n                      <jats:italic toggle=\"yes\">gluteus maximus<\/jats:italic>\n                      and\n                      <jats:italic toggle=\"yes\">gastrocnemius medialis<\/jats:italic>\n                      . The range of motion of hip abduction-adduction increased, and hip flexion-extension decreased during gait. Major contributors to reduced gait performance as identified using a LASSO were longer double support and step duration, and lower stride length, foot strike angle and variability in lateral step and hip adduction.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>The MyoSuit was not associated with improvements in functional performance in NMD. The use of the device was associated with kinematic alterations and the assistance provided alleviated recruitment of the rectus femoris. The proposed approach is promising but further tailoring of the device is required to address specific needs of individuals with severe muscle weakness.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/22143602251405914","type":"journal-article","created":{"date-parts":[[2026,1,8]],"date-time":"2026-01-08T18:09:33Z","timestamp":1767895773000},"page":"919-936","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":2,"title":["Multiparametric assessment of the MyoSuit, a bi-articular exoskeleton designed to assist gait and transfers in adults with neuromuscular diseases"],"prefix":"10.1177","volume":"13","author":[{"given":"Romain","family":"Feigean","sequence":"first","affiliation":[{"name":"Neuromuscular Investigation Center, Neuromuscular Physiology and Evaluation Laboratory"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cylia","family":"Afroun-Roca","sequence":"additional","affiliation":[{"name":"Neuromuscular Investigation Center, Neuromuscular Physiology and Evaluation Laboratory"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Clo\u00e9","family":"Guerrini","sequence":"additional","affiliation":[{"name":"Neuromuscular Investigation Center, Neuromuscular Physiology and Evaluation Laboratory"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juliette","family":"Souchu","sequence":"additional","affiliation":[{"name":"Neuromuscular Investigation Center, Neuromuscular Physiology and Evaluation Laboratory"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Frederic","family":"Fer","sequence":"additional","affiliation":[{"name":"MyoData Team"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guillaume","family":"Bassez","sequence":"additional","affiliation":[{"name":"Piti\u00e9-Salp\u00eatri\u00e8re Hospital, Assistance Publique H\u00f4pitaux de Paris"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Olivier","family":"Benveniste","sequence":"additional","affiliation":[{"name":"Piti\u00e9-Salp\u00eatri\u00e8re Hospital, Assistance Publique H\u00f4pitaux de Paris"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean-Yves","family":"Hogrel","sequence":"additional","affiliation":[{"name":"Neuromuscular Investigation Center, Neuromuscular Physiology and Evaluation Laboratory"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Damien","family":"Bachasson","sequence":"additional","affiliation":[{"name":"Neuromuscular Investigation Center, Neuromuscular Physiology and Evaluation Laboratory"},{"name":"INSERM, UMRS1158 Neurophysiologie Respiratoire Exp\u00e9rimentale et Clinique"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2026,1,8]]},"reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(12)61897-2"},{"key":"e_1_3_3_3_2","first-page":"207","article-title":"Exercise in neuromuscular disorders: a promising intervention","volume":"38","author":"Voet NBM","year":"2019","unstructured":"Voet NBM. 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